Application of doxycycline ad medicine for promoting cell proliferation
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- PEKING UNIV
- Publication Date
- 2007-02-14
- Estimated Expiration
- Not applicable · inactive patent
Smart Images
Figure 1 Figure 2 Figure 3
Abstract
Description
technical field
[0001] The present invention relates to the use of tetracyclines, in particular to the use of doxycycline as a drug for promoting cell proliferation. Background technique
[0002] Doxycycline is a tetracycline antibiotic, which is widely used clinically in the treatment of bacterial and protozoan infections. In recent years, it has been found that doxycycline and other tetracycline derivatives have other biological effects, and are currently being experimentally used in the clinical treatment of tumors , autoimmune diseases, periodontal disease, cerebral ischemia and hormone replacement therapy in postmenopausal women.
[0003] 1. Structure and antibacterial mechanism of doxycycline and other tetracyclines
[0004] Tetracycline drugs mostly have a similar four-ring core structure-hydrogenated tetraphenyl, and the different derivatives are only different in the substituting groups. Tetracyclines can be divided into natural products and semi-synthetic product...