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Medicinal composition for treating rhinitis, its preparing method and quality controlling means

A composition and drug technology, applied in the directions of drug combination, drug formula, drug delivery, etc., can solve the problem of lack of new theories on etiology and pathogenesis

Inactive Publication Date: 2007-03-07
国立创投(北京)医药科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Third, although desensitization therapy has many advantages over antihistamine therapy that can only improve symptoms, it needs to be continued for several years, and can only achieve the purpose of relieving symptoms, and there are reports of mental excitement and acute osteonecrosis.
However, the treatment principles and methods are still based on the oral medicine treatment based on dispelling wind and promoting lungs, diuresis and dampness, and invigorating the middle and replenishing qi. There is no new theory on its etiology and pathogenesis.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0100] Raw materials: Angelica dahurica 19kg, Magnolia magnolia 12kg, Xanthium 12kg, Goose Bubio 12kg, Scallion 12kg, Baibu 12kg, Astragalus 12kg, Schisandra 5.5kg.

[0101] Preparation method: 1) Angelica dahurica, Baibu, Schisandra chinensis plus 8 times the amount of 70% ethanol to reflux extract twice, each time for 2 hours, extract the ethanol and concentrate to a clear paste of 1.05-1.10 (50°C);

[0102] 2) Steam distilling Magnolia magnolii for 10 hours to extract the volatile oil, and retain the aqueous solution after oil extraction; the volatile oil is encapsulated with beta-cyclodextrin;

[0103] 3) Add 10 times the amount of water and decoct twice for 1.5 hours each time after mixing the medicinal residues of pungent catkins, cocklebur, astragalus, goose herbivore, and scallion, and then filter the decoction and reserve the filtrate for later use;

[0104] 4) Combine the aqueous solution after oil extraction in 2) and the filtrate in 3), concentrate to 1.05-1.10 (50...

Embodiment 2

[0108] Raw materials: Angelica dahurica 23kg, magnolia 16kg, cocklebur 16kg, geese not eating grass 16kg, scallion 16kg, 16kg 16kg, astragalus 16kg, schisandra 8.5kg

[0109] Preparation method: 1) Angelica dahurica, Baibu, Schisandra chinensis and 90% ethanol are refluxed and extracted 3 times, each time for 3 hours, the ethanol is recovered from the extract, and concentrated to a clear paste with a relative density of 1.05-1.10 (50°C);

[0110] 2) Add 10 times the amount of water to Magnolia magnolia, steam distill for 6 hours to extract the volatile oil, and keep the aqueous solution after oil extraction; the volatile oil is encapsulated with beta-cyclodextrin;

[0111] 3) Add 12 times the amount of water to decoct after mixing the medicinal residues of pungent catkins, cocklebur, astragalus, goose herbivore, and scallion, and then filter the decoction, and use the filtrate for later use;

[0112] 4) Combine the aqueous solution after oil extraction in 2) and the filtrate i...

Embodiment 3

[0116] Raw materials: Angelica dahurica 21.1kg, magnolia 14.1kg, cocklebur 14.1kg, geese not eating grass 14.1kg, scallion 14.1kg, 14.1kg basil, astragalus 14.1kg, schisandra 7.0kg

[0117] Preparation method: 1) Radix Angelicae dahurica, Baibu, Schisandra chinensis plus 5 times the amount of 80% ethanol to reflux extract 3 times, each time for 2 hours, filter, combine the ethanol extracts, recover ethanol, concentrate to a relative density of 1.05-1.10 (50 ℃) clear paste;

[0118] 2) Add 8 times the amount of water to Magnolia magnolii, steam distill for 6 hours, extract the volatile oil, and keep the aqueous solution after oil extraction; the volatile oil is encapsulated with beta-cyclodextrin;

[0119] 3) Add 12 times the amount of water after mixing the medicinal residues of pungent catkins, cocklebur, astragalus, goose herbivore, and scallion, decoct 3 times, 1 hour each time, filter, and use the filtrate for later use;

[0120] 4) Combine the aqueous solution after oil ...

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PUM

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Abstract

The invention discloses a medicinal composition for treating rhinitis, which is prepared from Chinese medicinal herbs including dahurian angelica root, flower bud of lily magnolia, siberian cocklebur fruit, centipeda, scallion stalk, roor of sessile stemona, astragalus root, and schisandra fruit. The invention The invention also discloses the method for preparing the medicinal composition and its quality control method.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a traditional Chinese medicine composition for treating rhinitis, and belongs to the field of traditional Chinese medicine. The invention also relates to the preparation method and quality control method of the pharmaceutical composition. Background technique [0002] Allergic rhinitis, also known as allergic rhinitis, is equivalent to rhinitis in traditional Chinese medicine. The external cause is the inhalation of natural allergens, and the internal cause is hereditary allergies. This disease is a global common disease and frequently-occurring disease. According to statistics, the prevalence rate is 10% to 40%, and the prevalence rate in my country is 37.74%. Unpleasant and painful, seriously affecting normal work and interpersonal communication, and long-term repeated attacks, can cause serious pathological damage, combined with nasal polyps, persistent cough and bronchial asthm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P11/02
Inventor 高丽王光耀田树革周铭心耿直
Owner 国立创投(北京)医药科技发展有限公司