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Method for aseptic production of animal raw serum in full sealing environment by multi-linked blood bag

An aseptic production, fully enclosed technology, applied in medical raw materials from mammals, hypodermic injection devices, etc., can solve the problem of not finding separated serum, and achieve the effect of speeding up commercial operation, reducing pollution, and wide application.

Inactive Publication Date: 2007-05-16
李勇
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In conclusion, so far, no technology has been found that collects blood and separates serum in the same closed sterile system

Method used

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  • Method for aseptic production of animal raw serum in full sealing environment by multi-linked blood bag

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Embodiment Construction

[0014] The catheter used in the implementation of the present invention is a medical plastic catheter, and the capacity of the blood bag is 500ml.

[0015] As shown in Figure 1, a method for aseptically producing raw animal serum with multiple blood bags fully enclosed is to connect the blood collection needle 1 to the catheter 2, connect the outlet of the catheter 2 to the inlet of the three-way pipe 3, and connect the outlet of the three-way pipe 3 Connect with the inlet of conduit 4 and conduit 5 respectively, conduit 4 and conduit 5 are respectively connected with the inlet of tee pipe 6, 7, and the outlet of tee pipe 6, 7 is connected with blood bag 12, 13 through conduit 8, 9, 10, 11 . , 10, 11 are equipped with control clips; blood collection needle 1 is inserted in the blood vessel of cattle neck, opens control clip, and cow blood flows in the blood bag 12 by conduit 4,8, similarly, opens control clip · cattle blood passes conduit 9,10 , 11 flow into blood bags 13, 14...

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Abstract

The invention relates to a method for producing animal serum with multiple blood bag sealed germ-free method, wherein it connects the blood taking needle via three-way tube and duct to the blood bag; the needle is inserted into the vessel of cow neck; opens the duct control clamper, the blood will pass the duct into blood bags (12, 13, 14, 15); uses thermal combiner to seal the ducts (8, 9, 10, 11) at A, B, C, and D positions; cuts off the ducts (8, 9, 10, 11); keeping the temperature of bags (12, 13, 14, 15), condensing the blood and evoluting the serum, and decentering the bags (12, 13, 14, 15), to separate the blood and serum; opening the clamper, protruding the serum into bags (16, 17); then uses thermal combiner to seal E, F, G, H positions of ducts (18, 19, 20, 21); cuts off bags (16, 17). The invention can avoid additional device, to realize the production in one sealed system, and avoid pollution.

Description

technical field [0001] The invention relates to a fully enclosed aseptic production method of raw animal serum. Background technique [0002] Animal serum (mainly newborn bovine serum) is the main raw and auxiliary material in the production of biological products and an important reagent in scientific research. It is required that this serum product is free from foreign substances (microorganisms, phages, endotoxins, etc.) It has good ability to promote cell growth and reproduction. Taking newborn bovine serum as an example, in order for the finished serum to meet the "Quality Control Standards for Raw and Auxiliary Materials of Biological Products in China", the raw material serum must at least meet the quality control standards for bacteria, endotoxins, and phages. However, in the production of existing domestic raw material serum, blood collection and separation are carried out in two stages in different container systems. Exposure to pollution opportunities: The first...

Claims

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Application Information

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IPC IPC(8): A61M5/44A61K35/16
Inventor 李勇
Owner 李勇
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