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Medicinal granule for treating cerebral apoplexy and preparation process thereof

A granule, a technology for cerebral apoplexy, applied in the field of pharmaceutical preparations for the treatment of cerebral apoplexy and their preparation, can solve the problems of poor stability, high production cost, inconvenient carrying, storage and transportation, etc. No effect on heart rate and blood pressure

Inactive Publication Date: 2007-05-30
YUNNAN BAIYAO GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The patent application with the Chinese patent application number ZL99114839.8.1 discloses a "drug for treating stroke and its production process". In the tank, add water to decoct and extract, filter the extract, and concentrate and prepare an oral liquid (mixture), but this invention uses a liquid preparation, which has poor stability, high production cost, and inconvenient storage and transportation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Take 100g of Sansevieria chinensis 50g, put it into a multifunctional extraction tank, add water to decoct 2 times after coarse crushing, add 10 times the amount of water to decoct for 2.0 hours each time, combine the decoction, filter, combine the filtrate with the above aqueous solution, and concentrate to The relative density is 1.18∽1.19 (60°C). Let it cool to obtain the extract, add ethanol to the extract to make the alcohol content reach 60%, let it stand for 18 hours, filter, and recover the ethanol from the filtrate under reduced pressure until the relative density is 1.15 ∽1.30 (6) ℃), to get the medicinal extract, add powdered sugar and dextrin mixture (ratio is 1: 1) by 2.0 times of the medicinal extract, add 0.7% carboxymethyl fiber by weight percentage by 2% of the medicinal extract amount Sodium plain aqueous solution is used as a binder, spray granulated, dried, sterilized, mixed evenly, and packaged.

Embodiment 2

[0044] Take 200g of Sansevieria sativa and 100g of heavy pendant, put it into a multi-functional extraction tank, add water to decoct twice, each time add 10 times the amount of water to decoct for 2.0 hours, combine the decoction, filter, combine the filtrate with the above aqueous solution, and concentrate When the relative density is 1.18∽1.19 (60°C), let it cool to obtain the extract, add ethanol to the extract to make the alcohol content reach 60%, let it stand for 18 hours, filter, and recover the ethanol from the filtrate under reduced pressure until the relative density is 1.15∽1.30 (60°C) to obtain extract, add powdered sugar and dextrin mixture (ratio: 2:1) according to 2.5 times the amount of extract, add 0.7% carboxymethyl fiber according to 2% of extract amount Sodium plain aqueous solution is used as a binder, spray granulated, dried, sterilized, mixed evenly, and packaged.

Embodiment 3

[0045] Embodiment 3 (sugar-free type):

[0046]Take 100g of Sansevieria chinensis 100g, put it into a multifunctional extraction tank, add water to decoct 2 times after coarse crushing, add 10 times the amount of water to decoct for 2.0 hours each time, combine the decoction, filter, combine the filtrate with the above aqueous solution, and concentrate to The relative density is 1.18∽1.19 (60°C). Let it cool to obtain the extract, add ethanol to the extract to make the alcohol content reach 60%, let it stand for 18 hours, filter, and recover the ethanol from the filtrate under reduced pressure until the relative density is 1.15 ∽1.30 (60°C) to obtain the extract, add lactose and dextrin mixture (ratio: 1:3) according to 3.5 times the amount of the extract, add 0.7% sodium carboxymethylcellulose according to the weight percentage of 2% of the extract The aqueous solution is used as a binder, and 0.5% stevioside is used as a flavoring agent, which is sprayed, granulated, dried, ...

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PUM

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Abstract

The invention relates to a medicinal preparation prepared from Chinese herbs as raw materials, particularly to a medicinal preparation for treating cerebral apoplexy and its preparing process. The medicament is prepared into the form of granules comprising the following raw materials (by weight portion): chloris virgata swartz 100-200, Moghania philippinensis 50-100.

Description

technical field [0001] The invention relates to a pharmaceutical preparation prepared from plant Chinese herbal medicines, in particular to a pharmaceutical preparation for treating cerebral apoplexy and a preparation method thereof. Background technique [0002] The patent application with the Chinese patent application number ZL99114839.8.1 discloses a "drug for treating stroke and its production process". In the tank, add water to decoct and extract, filter the extract, and concentrate and prepare an oral liquid (mixture), but this invention adopts a liquid preparation, which has poor stability, high production cost, and inconvenient storage and transportation. Contents of the invention [0003] The purpose of the present invention is to overcome the deficiencies of the prior art and provide a drug granule for treating cerebral apoplexy which has good stability, low production cost and is easy to carry, store and transport. [0004] Another object of the present invent...

Claims

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Application Information

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IPC IPC(8): A61K36/64A61K9/16A61P9/10
Inventor 万近福高崇昆王真张立群
Owner YUNNAN BAIYAO GROUP
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