Preparation of shikimic acid

A technology of shikimic acid and technology, applied in the field of plant resources, can solve the problems of long industrialized production process, complicated operation and high cost

Inactive Publication Date: 2007-06-20
邓薏
View PDF0 Cites 15 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the strong polarity and small molecular weight of shikimic acid, and the star anise fruit contains a large amount of sugar and a large amount of volatile oil (2-6%), it is not easy to extract, separate and purify, and the extract and extract need to be degreased, etc., and the industrial production process is long. , high equipment requirements, complex operation, relatively high cost
In addition, due

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation of shikimic acid
  • Preparation of shikimic acid
  • Preparation of shikimic acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0025] 1. Star anise, crushed, add 10 times the amount of water, stir from time to time, soak for 20 minutes, filter, collect the filtrate; add 8 times the amount of water, 6 times the amount of water to the residue, and operate in the same way. Combine the extracts, evaporate and concentrate to 2:1 (crude drug g / ml), add alcohol to 80% alcohol content, let it stand, filter the supernatant, recover ethanol, decolorize with activated carbon, dry, and the yield of shikimic acid is 4.32% ( Calculated according to shikimic acid, the same below), the content is 38.9%. The residue can be used to extract star anise oil.

[0026] 2. Star anise water steam distills the residue after extracting the star anise oil, filter the water, leave it in place, add 10 times more water to the residue and decoct for 1 hour, filter, combine the two filtrates, concentrate to 2:1 (raw material g / ml), Add alcohol to 80% alcohol content, precipitate, filter, take the filtrate to flow out through D101 ma...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

Production of shikimic acid and use of Chinese Star Anise oil residual waste are disclosed. The process is carried out by taking Chinese Star Anise or Chinese Star Anise leaf as raw materials, crushing, decoction extracting by water or agitating to fast extract, depositing by alcohol, removing impurities, de-coloring by active carbon or porous resin, treating by lead acetate or enriching resin while anion-exchanging, crystallizing and re-crystallizing to obtain various-purity shikimic acid. It's cheap and convenient and has colorful raw materials.

Description

technical field [0001] The invention relates to a new application of plant resources and a new technique for extracting and preparing shikimic acid. The application of this technology to extract and prepare shikimic acid has the advantages of abundant raw materials, simple and convenient process, and low cost. Background technique [0002] Shikimic acid has significant analgesic and hemodynamic improvement effects, and is also an important raw material for the preparation of various drugs. Today, shikimic acid is extracted from the traditional Chinese medicine star anise, and the fruit of star anise generally contains about 3-8% shikimic acid. It is usually extracted by reflux extraction with high concentration of organic solvents such as methanol, ethanol or acetone, and the extract is separated by organic solvents such as n-butanol, ethyl acetate, etc. or column chromatography, and then obtained by further repeated recrystallization. Due to the strong polarity and small ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): C07C51/42C07C62/32
Inventor 邓薏
Owner 邓薏
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap