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Temperature control method for liquid components in analyzing instrument, the analyzing instrument and analyzing apparatus

a temperature control method and liquid component technology, applied in the direction of instruments, chemistry apparatus and processes, laboratory glassware, etc., can solve the problems of high energy consumption of temperature control methods, poor energy efficiency of temperature of reaction liquid in micro-devices, and high energy consumption of conventional temperature control methods, so as to achieve low energy consumption and not make the analyzing apparatus large.

Inactive Publication Date: 2006-04-06
ARKRAY INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention provides a method and apparatus for controlling the temperature of a liquid in an analyzing instrument without using large amounts of energy or requiring large equipment. The method involves using a heating layer that is heated by a magnetic flux passed through the instrument. The heating layer can be made of a thin metal film or a conductive resin material. The heating layer can be formed by direct film formation or by working the material into a sheet and affixing it to the instrument. The temperature of the liquid can be controlled by monitoring its temperature and adjusting the magnetic flux passed through the instrument. The invention can be applied to microdevices for analyzing small samples.

Problems solved by technology

These temperature control methods have the drawback of high energy consumption because it is necessary to heat block 91 or drive heat generator 93 when raising the temperature of reaction liquid 90.
As a result, when controlling the temperature of a reaction liquid in microdevice energy efficiency is poor because the amount of heat used for raising the temperature of reaction liquid 90 is small in comparison with the amount of heat transmitted by heating media 91 and 93.
Thus, conventional temperature control methods have had the drawback of high energy consumption.
Consequently, it has been difficult to apply conventional temperature control methods to analyzing apparatuses driven by internal power sources such as small batteries (for example, batteries widely used for household use), and even if the aforementioned methods were applied to a small analyzing apparatus it would not be practical because the actual working time of the analyzing apparatus would be extremely short.
And while the shortness of the actual working time can be improved by increasing the capacity of the internal power source, this impedes miniaturization of the analyzing apparatus and detracts from wide use.
Power can also be supplied from an external source, but in that case an adapter is necessary to connect the analyzing apparatus to the external power source, making it less portable and also creating problems for use in other locations.

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  • Temperature control method for liquid components in analyzing instrument, the analyzing instrument and analyzing apparatus
  • Temperature control method for liquid components in analyzing instrument, the analyzing instrument and analyzing apparatus
  • Temperature control method for liquid components in analyzing instrument, the analyzing instrument and analyzing apparatus

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embodiments 1 through 5

[0029] Embodiments 1 through 5 of the present invention are explained below with reference to FIGS. 1 through 8.

first embodiment

[0030] First, the present invention is explained with reference to FIGS. 1 through 3.

[0031] The analyzing apparatus X shown in FIG. 1 has an analyzing function for analyzing a sample using analyzing instrument 1, and a temperature control function for controlling the temperature of a liquid 10 held on measurement site 11Cb of analyzing instrument 1. To exercise these functions, analyzing apparatus X includes mount 20, temperature detector 21, control calculator 22, magnetic generating coil 23, AC voltage applier 24, light source 25, light detector 26, concentration calculator 27 and controller 28.

[0032] Mount 20 is for holding analyzing instrument 1. Temperature detector 21 is embedded in mount 20. This temperature detector 21 is arranged so as to be in a region directly underneath liquid 10 (measurement site 11Cb) held on analyzing instrument 1 when analyzing instrument 1 is mounted on mount 20. This means that the temperature measured by temperature detector 21 is closer to the a...

second embodiment

[0054] Next, the present invention is explained with reference to FIG. 5.

[0055] In the analyzing instrument 3 shown in FIG. 5 reagent is not supplied to analyzing instrument 3 from the outside, and instead analyzing instrument 3 already holds reagent in reagent part 30.

[0056] In analyzing instrument 3 measurement site 32 is provided partway along channel 31, reagent part 30 is held in this measurement site 32, and heating layer 33 is provided directly above measurement site 32. This analyzing instrument 3 is designed so that sample introduced from sample inlet 34 moves by capillary action towards air vent 35, and is supplied to measurement site 32.

[0057] In measurement site 32 reagent 30 is dissolved by the supply of sample to construct a liquid reaction system. Thermal energy generated in heating layer 33 by the passage of magnetic lines of force through heating layer 33 can be supplied to the liquid (liquid phase reaction system) held in this measurement site 32.

[0058] Next, th...

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Abstract

This invention relates to a technique for adjusting the temperature of a liquid held on an analyzing instrument (1) to a target value. The invention provides a temperature control method wherein thermal energy is supplied to liquid (10) by passing a magnetic flux across an analyzing instrument (1) for raising the temperature of the liquid. The invention also provides an analyzing instrument (1) and analyzing apparatus (X) which are suited to raising the temperature of a liquid (10) using a magnetic flux.

Description

TECHNICAL FIELD [0001] The present invention relates to a technique for adjusting the temperature of a liquid held on an analyzing instrument to a target value, in analysis of a sample with use of the analyzing instrument. BACKGROUND ART [0002] Methods of analyzing a sample include methods in which the reaction liquid resulting from the reaction of a sample and a reagent is analyzed by optical means. Such analysis is accomplished for example by mounting an analyzing instrument which provides a reaction field on an analyzing apparatus equipped with an optical system capable of emitting and receiving light (see for example JP-A 8-114539). In this case, it is desirable to adjust the temperature of the analyzing instrument (particularly the reaction liquid), and to react the sample and reaction liquid at roughly the same temperature for each measurement so as to minimize analysis error and increase the reliability of the analysis results. In systems using enzyme reactions in particular,...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): G01N35/00G01N1/28B01L3/00B01L7/00G01N21/01G01N21/78G01N27/447
CPCB01L3/502715B01L7/00Y10T436/115831G01N2035/00415G01N27/44734
Inventor KITAMURA, SHIGERU
Owner ARKRAY INC