Novel anelgesic combination

a technology of anelgesics and combination, applied in the direction of dragees, coatings, pharmaceutical delivery mechanisms, etc., can solve the problems of tramadol may produce certain side effects, still has certain commonly reported side effects, and may have serious upper gastrointestinal complications. achieve the effect of reducing the pain scor
US20080031950A1Inactive Publication Date: 2008-02-07NECTID INC

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
NECTID INC
Publication Date
2008-02-07
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method of administering a pharmaceutical combination comprising an NSAID and a slow release tramadol to a mammal in need of thereof. This invention further discloses an analgesic combination comprising an NSAID and a slow release tramadol for treating pain and pain related conditions.
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Description

FIELD OF THE INVENTION

[0001] The present invention provides a method of treating pain and pain related conditions by administering to a patient in need thereof, a therapeutically effective amount of an NSAID and a slow release tramadol combination. The present invention further a pharmaceutical composition comprises of a slow release Tramadol and an immediate release NSAID such as Naproxen BACKGROUND OF THE INVENTION

[0002] Tramadol (FORMULA 1) is a centrally acting synthetic opioid analgesic. It is chemically (±) cis-2-[(dimethylamino) methyl]-1-(3-methoxyphenyl)cyclo-hexanol hydrochloride. It is commercially available in form of its hydrochloride salt (Formula II) as Ultram tablets. Tramadol is indicated in the treatment of the management of moderate to moderately severe pain in adults.

[0003] Tramadol is not an NSAID and doesn't have the increased risk of stomach ulceration and internal bleeding associated with non-steroidal anti inflammatory drugs (NSAID). However, it still ha...

Claims

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