Novel anelgesic combination
Patent Information
- Authority / Receiving Office
- US · United States
- Patent Type
- Applications(United States)
- Current Assignee / Owner
- NECTID INC
- Publication Date
- 2008-02-07
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
FIELD OF THE INVENTION
[0001] The present invention provides a method of treating pain and pain related conditions by administering to a patient in need thereof, a therapeutically effective amount of an NSAID and a slow release tramadol combination. The present invention further a pharmaceutical composition comprises of a slow release Tramadol and an immediate release NSAID such as Naproxen BACKGROUND OF THE INVENTION
[0002] Tramadol (FORMULA 1) is a centrally acting synthetic opioid analgesic. It is chemically (±) cis-2-[(dimethylamino) methyl]-1-(3-methoxyphenyl)cyclo-hexanol hydrochloride. It is commercially available in form of its hydrochloride salt (Formula II) as Ultram tablets. Tramadol is indicated in the treatment of the management of moderate to moderately severe pain in adults.
[0003] Tramadol is not an NSAID and doesn't have the increased risk of stomach ulceration and internal bleeding associated with non-steroidal anti inflammatory drugs (NSAID). However, it still ha...