Multi-phase bacterially-synthesized-nanocellulose biomaterials and method for producing the same
a biomaterial and nanocellulose technology, applied in the field of multi-phase biomaterials, can solve the problems of only controlling the structure and properties of the combined mixture, requiring additives to produce novel biomaterials on bnc basis, and integrating additives bearing the risk of possible allergic reactions
Inactive Publication Date: 2013-01-03
JENACELL
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- Abstract
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Benefits of technology
The invention relates to a method for producing multi-phase biomaterials based on bacterially synthesized nanocellulose, which can be used in a variety of applications such as medicine, engineering, and food industry. The method allows for the modification of the material after its synthesis without the need for disadvantageous additives or composite formations. The resulting materials have improved mechanical strength, elasticity, transparency, water balance, and biocompatibility. The invention also provides new structures and properties for the material, such as permeability, filter function, and scaffolding. The addition of certain additives during the biosynthesis process can significantly modify the material's structure and properties.
Problems solved by technology
However, these in situ methods have the disadvantage that they require additives to produce novel biomaterials on BNC basis.
Thus, the structure and the properties combined with it can only be controlled by using water-soluble organic, inorganic substances or polymers and solid particles.
Furthermore, in contrast to pure BNC the integrated additives bear the risk of possible allergic reactions if are used as medical products.
However, these methods have the disadvantage that they require two production steps (synthesis of BNC and its modification) for developing novel BNC.
Moreover, the post modification modifies the BNC partly to such an extent that the unique structure and consequently the excellent properties are lost.
In addition to this, these methods require the disadvantageous use of additives, too.
Moreover, the accessibility of multi-phase biomaterial systems is strongly restricted because only homogeneous structures can be achieved due to a resulting composite formation.
Method used
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Embodiment Construction
[0029]The invention will be explained in more detail by virtue of the following embodiments illustrated in the figures.
[0030]They show:
[0031]FIG. 1: Bacterially synthesized nanocellulose (BNC) consisting of a plurality of different bacterial cellulose networks that form a common homogeneous phase system
[0032]FIG. 2: BNC consisting of two different bacterial cellulose networks each of them forming a separate layered single phase
[0033]FIG. 3: BNC with two different bacterial cellulose networks that form a layered phase system consisting of two layered single phases and one combined, homogeneous phase
[0034]FIG. 1 shows bacterially synthesized nanocellulose (BNC biomaterial) that, according to the invention, consists of a plurality (two in the example) of different bacterial cellulose networks forming a common phase system of one combined homogeneous phase (1).
[0035]This phase system is synthesized from two kinds of Gluconacetobacter strains, in the example ATCC 23769 and DSM 11804, in ...
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Abstract
Multiphase biomaterials are provided which are based on bacterially synthesized nanocellulose (BNC) including at least two different bacterial cellulose networks. To this end, a culture median is inoculated with at least two different cellulose-producing bacterial strains.
Description
BACKGROUND OF THE INVENTION[0001]The invention relates to multi-phase biomaterials based on bacterially synthesized nanocellulose and a method for producing same.[0002]The proposed BNC materials are suitable for a broad range of applications, for example in medicine (wound dressings, great variety of implants), in engineering (membranes, foils, barrier layers) and in food industry (zero-calorie nutrition, packaging) due to highly versatile determinable structures and material properties).[0003]This application-designed method for obtaining defined structures and properties that are even new for BNC materials in particular refers to mechanical strengths, elasticity, transparency and water balance, particularly the capability to re-expand appropriately and completely after drying, as well as so-called filter / membrane functions (permeability), scaffold-properties (pore system, surface characteristics, colonization by cells) and bio-compatibility (body compatibility, endothelialization,...
Claims
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Patent Timeline
Login to View More IPC IPC(8): C12P19/04B32B9/04C08B15/00
CPCA61L27/48A61L2400/12C08B15/10C12P19/04Y10T428/31978C08L1/02
Inventor HESSLER, NADINESULTANOVA, BARNOKLEMM, DIETER
Owner JENACELL