Moisture-proof coating method for Chinese medicine granule
A Chinese medicine formula granule and coating technology, which is applied in the coating of traditional Chinese medicine formula granules to prevent moisture, and the field of traditional Chinese medicine formula granules to prevent moisture, can solve the problems of large dosage, low drug concentration, and ineffective curative effect, and achieve less dosage and convenient prescription The effect of deployment and convenient clinical application
Active Publication Date: 2007-10-17
JIANGYIN TIANJIANG PHARMA
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AI Technical Summary
Problems solved by technology
However, the prepared preparation has low drug concentration and large dosage, and the curative effect is not obvious; the coating method is moisture-proof, and the tumbling coating method is more commonly used, and is mainly suitable for the coating of tablets to prevent moisture. The coating materials include cellulose ( Such as hydroxypropyl methylcellulose), acrylic resins (such as acrylic resin No. IV), etc., are all hydrophobic materials, insoluble in water, and are only suitable for tablets taken orally as coating materials, not Suitable for Chinese medicine formula granules taken in the form of infusion as coating material
Method used
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Experimental program
Comparison scheme
Effect test
Embodiment 1
[0022] Take 1000g of wolfberry traditional Chinese medicine formula granules, add 50g of glyceryl behenate and 3g of micro-powdered silica gel, mix thoroughly, put in a homogeneous emulsifier, and stir for 15 minutes at a stirring speed of 190r / min at 76°C to make a moisture-proof coating Wolfberry formula granules.
Embodiment 2
[0024] Take 1000g of Ganoderma lucidum formula granules, add 30g of glyceryl behenate and 2g of micro-powdered silica gel, mix well, put it in a homogeneous emulsifier, and stir for 18 minutes at 78°C with the stirring blade at a speed of 180r / min to make a moisture-proof coated Ganoderma lucidum formula particles.
Embodiment 3
[0026] Take 1000g of frankincense formula granules, add 30g of glyceryl behenate and 4g of micro-powdered silica gel, mix thoroughly, put in a homogeneous emulsifier, and stir for 18 minutes at 77°C with a stirring blade at a speed of 185r / min to make a moisture-proof coating frankincense formula particles.
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Abstract
The present invention relates to moisture-proof coating method for Chinese medicine granule, and belongs to the field of moisture-proof technology for Chinese medicine granule. The method includes mixing Chinese medicine granule in 100 weight portions, glyceryl behenate in 1-5 weight portions and fine silica gel powder in 0.1-1 weight portion through stirring in a homogenizer at 75-80 deg.c for 15-20 min to prepare the moisture-proof coated Chinese medicine granule. The glyceryl behenate has low smelting point and is favorable to taking the coated Chinese medicine granule together with hot water, the fine silica gel powder can increase the flowability of the granule and promote the disintegration of granule, and the combination of glyceryl behenate and fine silica gel powder forms excellent Chinese medicine granule coating material.
Description
Technical field: [0001] The invention relates to a traditional Chinese medicine formula granule, in particular to a coating and moisture-proof method for the traditional Chinese medicine formula grain. It belongs to the technical field of moisture-proofing of traditional Chinese medicine formula granules. Background technique: [0002] Traditional Chinese medicine formula granules are granules made from traditional Chinese medicine decoction pieces by extraction, low-temperature concentration, and drying. It can not only be used for flexible clinical prescriptions, but also can be used as industrial raw materials for traditional Chinese medicine preparations. [0003] Traditional Chinese medicine formula granules are dry extract powder made by extracting Chinese herbal pieces with water. The dry extract contains sugar, gum, protein, tannin, inorganic salts and other ingredients that are easy to absorb moisture, which are easy to absorb moisture and agglomerate, which affect...
Claims
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IPC IPC(8): A61K9/16A61J3/02A61K47/14A61K36/00
Inventor 徐以亮王元清周嘉琳李松
Owner JIANGYIN TIANJIANG PHARMA