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Medicinal composition for promoting bone fracture healing and its preparing method

A technology of fracture healing and composition, applied in the field of pharmaceutical composition, which can solve the problems of scientific composition, simplicity, and unfavorable taking by patients

Active Publication Date: 2007-10-24
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sanhua Jiegu Powder is composed of 18 Chinese herbal medicines such as Panax notoginseng, saffron, and dried blood. The main saffron in the prescription is a precious medicinal material, and the medicine is a powder, which is not conducive to taking by patients.
At present, there is no Chinese patent medicine with scientific and simple prescription and obvious pharmacological effects to promote fracture healing.

Method used

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  • Medicinal composition for promoting bone fracture healing and its preparing method
  • Medicinal composition for promoting bone fracture healing and its preparing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1. A pharmaceutical composition for promoting fracture healing, which is a medicament made of the following raw materials in proportion by weight, (unit: gram)

[0051] drynaria 10, sarcomas 10,

[0052] Chuanduan 10, Astragalus 20.

[0053] The oral liquid is prepared by conventional techniques.

Embodiment 2

[0054] Example 2. A pharmaceutical composition for promoting fracture healing, which is a medicament made of the following raw materials in proportion by weight, (unit: gram)

[0055] drynaria 10, sarcomas 10,

[0056] Chuanduan 10, Astragalus 20.

[0057] Its preparation method steps are as follows:

[0058] (1) Take Dipsacus, use 90% ethanol as solvent, soak for 36 hours, percolate at a speed of 1ml per minute, collect the percolation liquid until the total saponins are completely drained; or reflux with 85% ethanol to extract 2 Each time, the amount of ethanol solution is more than 4 times each time, each reflux time is 1 hour, filter, and combine the filtrate; the percolation or reflux extract is decolorized by alumina or activated carbon, filtered, and the ethanol is recovered and concentrated to a thick paste. Add 1 times the amount of water, carry out degreasing treatment after water sinking, absorb the degreasing liquid through a macroporous resin column and elute w...

Embodiment 3

[0065] Example 3. A pharmaceutical composition for promoting fracture healing, which is a medicament made of the following raw materials in proportion by weight, (unit: gram)

[0066] drynaria 20, sarcomas 20,

[0067] Chuanduan 20, Astragalus 30.

[0068] Its preparation method steps are as follows:

[0069] (1) Take Dipsacus, use 95% ethanol as solvent, soak for 48 hours, percolate at a speed of 2ml per minute, collect the percolation liquid until the total saponins are completely drained; or use 95% ethanol to reflux extract 4 Once, the amount of ethanol solution is more than 4 times each time, and the reflux time is 2.5 hours each time, filter and combine the filtrate; the percolation or reflux extract is decolorized by alumina or activated carbon, filtered, and the ethanol is recovered and concentrated to a thick paste. Add 10 times the amount of water, degrease after water sinking, absorb the degreasing liquid through a macroporous resin column and elute with ethanol ...

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Abstract

The present invention relates to a Chinese medicine composition for promoting union with obvious therapeutic effect. Said Chinese medicine composition is made up by using 4 Chinese medicinal materials of drynaria root, sarcandra twig and leaf, dipsacus root and astragalus root, Besides, said invention also provides its preparation method and concrete steps.

Description

technical field [0001] The invention relates to a pharmaceutical composition using Chinese herbal medicine as a raw material, in particular to a pharmaceutical composition for promoting fracture healing, and also relates to a preparation method of the pharmaceutical composition. Background technique [0002] At present, the treatment methods for fractures are mainly surgical reduction and fixation, but no matter how advanced the surgical method is, it usually takes 3 months or longer for fractures to heal, so that the fractured people lose the ability to work or even take care of themselves for a long time ability. In addition, due to the existence of stress shielding, osteoporosis and bone atrophy are obvious in the fracture treatment with strong internal fixation, and re-fracture is prone to occur after the internal fixation is removed; fracture treatment with elastic fixation is difficult to control the movement of the bone end, which is easy to c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/898A61K36/11A61K36/185A61K36/481A61K9/19A61K9/00A61P19/08
Inventor 肖伟戴翔翎凌娅李明慧
Owner JIANGSU KANION PHARMA CO LTD