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Medical application of fruit extraction of miracle fruit

A technology of Sacred Fruit and extract, which is applied in the field of medical application of Sacred Fruit extract, and can solve problems such as being unable to effectively inhibit

Active Publication Date: 2009-11-18
SENYUH FARM SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, regardless of insulin injection or oral hypoglycemic drugs, although they can effectively control blood sugar, they cannot effectively inhibit the heart, blood vessels, eyes, kidneys, and nervous system diseases in diabetic patients.

Method used

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  • Medical application of fruit extraction of miracle fruit
  • Medical application of fruit extraction of miracle fruit
  • Medical application of fruit extraction of miracle fruit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1: Preliminary test on the regulation of blood sugar by Mira holy fruit mixture

[0037] 1.1 Source of experimental animals

[0038]Male Wistar rats were obtained from the Animal Center of National Cheng Kung University School of Medicine, Taiwan, China, and were all over 8 weeks old and weighed between 200 and 250 grams. The rats used are all raised in the center, the air conditioner maintains the room temperature at 25±1°C, and the light time and dark time are 12 hours respectively. Rats had free access to food and water.

[0039] 1.2 Induction of insulin-dependent (type 1) diabetic rats

[0040] According to the commonly used method, after the 8-week-old rats of the aforementioned strain were fasted, they were anesthetized by intraperitoneal injection of 30 mg / kg pentobarbital, and 65 mg / kg of streptozotocin (STZ) was injected from the femoral vein; STZ was dissolved in Sodium citrate (10mmol / L) pH4.5 saline. One week after the injection, blood was collec...

Embodiment 2

[0064] Embodiment 2: Control test to normal and diabetic rats

[0065] 2.1 Regulating test of Mira holy fruit mixture on normal rats

[0066] Rats that had been fasted overnight were orally given different doses of Mira saccharomyces mixture, respectively 40 mg / kg, 60 mg / kg, and 80 mg / kg, and then anesthetized with pentobarbital to draw blood. see image 3 And as shown in Table 3, after 60 minutes, it was found that the 40mg / kg dose of Mira holy fruit mixture could produce a hypoglycemic effect in normal rats, and the blood sugar level dropped from the original 108.4±2.0mg / dL to 98.7±2.9mg / dL. dL, the hypoglycemic percentage reached 9.0±2.3%, and the hypoglycemic effect appeared in a dose-dependent manner. In addition, the hypoglycemic effect of the Mira holy fruit mixture also increased with time, and its effect would reach the maximum after 90 minutes of force-feeding.

[0067] Table 3. The hypoglycemic effect of force-feeding Mila ginseng fruit mixture on normal rats

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PUM

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Abstract

The invention relates to a medical usage of the miracle fruit extract, comprising the usage of the miracle fruit extract in preparing medicines or foods capable of adjusting and controlling the first and second diabetes and improving insulin fastness. The invention also relates to a medical composition capable of controlling blood sugar, comprising curable-effective miracle fruit mixture. The invention also relates to a medical composition capable of improving insulin release comprising curable-effective miracle fruit mixture. And the invention also relates to food capable of controlling blood sugar.

Description

technical field [0001] The present invention relates to the medical use of a kind of fruit extract of Sacred Mela, especially its use in preparing food and pharmaceutical compositions that can regulate blood sugar. The present invention also relates to a food containing a mixture of Sacred Mela fruit and pharmaceutical compositions. Background technique [0002] According to statistics from the Department of Health of the Executive Yuan, the number of diabetic patients is growing at an alarming rate year by year, making diabetes one of the top ten causes of death for humans. In addition, diabetes and cerebrovascular disease, high blood pressure, and heart disease among the top ten causes of death often occur together, making the disease difficult to control. This is a very heavy burden and loss for individuals, families, society and even the country. Therefore, the regulation of diabetes is an urgent and important issue. [0003] Clinically, diabetes is divided into two c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/258A61K36/00A61K9/00A61P3/10A61P3/06
Inventor 林美玲郑瑞棠
Owner SENYUH FARM SCI