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Blood fat lowering composition medicine and its preparation

A medicine and product technology, applied in the field of lipid-lowering combination medicine and its preparation, can solve problems such as unsuitable for long-term use, liver and kidney function damage, inconvenience of malt decoction, etc., and achieve easy to carry and take, good curative effect, single herb little effect

Inactive Publication Date: 2007-08-08
BEIJING SHENZHOU XIANGRUI PHARMA SCI & TECH DEV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] To sum up, Western medicine has great limitations in the field of lipid-lowering: 1) damage to liver and kidney function; 2) strong side effects, not suitable for long-term use
However, Gynostemma gynostemma is bitter and tastes bad; hawthorn contains a lot of organic acids, which can easily cause gastrointestinal discomfort after taking a large amount; decoction of malt also has many inconveniences.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] This embodiment provides a combination medicine, which includes the following raw materials and parts by weight:

[0039] Gypenoside 3.50;

[0040] Hawthorn total flavonoids 9.00;

[0041] Maltose 2.20.

[0042] The present invention also provides the preparation method of the aforementioned combination medicine as follows:

[0043] The raw materials are mixed, decocted, and concentrated to prepare a pharmaceutically acceptable dosage form.

[0044] The uses and effects of the combination medicine provided in this embodiment are as follows:

[0045] Compatible with the above three drugs, the formula is novel, the ratio is reasonable, the curative effect is obvious, and it can be taken for a long time. Animal experiments have proved that the product provided in this example has a good lipid-lowering effect, which can reduce serum total cholesterol (TC) by 35%, low-density lipoprotein cholesterol (LDL-C) by 51%, and increase high-density lipoprotein cholesterol. (HDL-C) 46%. ...

Embodiment 2

[0047] The embodiment provides a combination medicine, including the raw materials and the weight parts thereof as follows:

[0048] Gypenosides 6.40;

[0049] Hawthorn total flavonoids 5.00;

[0050] Maltose 3.60.

[0051] The present invention also provides the preparation method of the aforementioned combination medicine as follows:

[0052] The raw materials are mixed, decocted, and concentrated to prepare a pharmaceutically acceptable dosage form.

[0053] The uses and effects of the combination medicine provided in this embodiment are as follows:

[0054] Compatible with the above three drugs, the formula is novel, the ratio is reasonable, the curative effect is obvious, and it can be taken for a long time. Animal experiments have proved that the product provided in this example has a good lipid-lowering effect, which can reduce serum total cholesterol (TC) by 30%, low-density lipoprotein cholesterol (LDL-C) by 45%, and increase high-density lipoprotein cholesterol. (HDL-C) ...

Embodiment 3

[0056] The embodiment provides a combination medicine, including the raw materials and the weight parts thereof as follows:

[0057] Gypenosides 4.50;

[0058] Ginsenoside Rb 1 1.62;

[0059] Hawthorn total flavonoids 6.00;

[0060] Maltose 2.60;

[0061] Maltodextrin 1.00.

[0062] The present invention also provides the preparation method of the above-mentioned combination medicine as follows:

[0063] The raw materials are mixed, decocted, and concentrated to prepare a pharmaceutically acceptable dosage form.

[0064] The uses and effects of the combination medicine provided in this embodiment are as follows:

[0065] Compatible with the above-mentioned drugs, the formula is novel, the ratio is reasonable, the curative effect is obvious, and it can be taken for a long time. Animal experiments have proved that the product provided in this example has a good lipid-lowering effect, which can reduce serum total cholesterol (TC) by 36%, low-density lipoprotein cholesterol (LDL-C) b...

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Abstract

The invention relates to an antihyperglycemic composition and its preparing process, wherein the composition comprises the following raw materials (by weight portion): Gynostemma pentaphylla glycosides 3.50-6.40, haw thorn leaf flavones 5.00-9.00, barley sugar 2.20-3.60, or alcohol extract of Gynostemma pentaphylla (calculated by Gynostemma pentaphylla glycosides) 3.50-6.40, aqueous extract of haw thorn (calculated by haw thorn flavones) 5.00-9.00, aqueous extract of malt (calculated by malt sugar) 2.20-3.60.

Description

Technical field [0001] The invention relates to a lipid-lowering combination medicine and a preparation method thereof. Background technique [0002] With the acceleration of my country's comprehensive construction of a well-off society and the improvement of people's living standards, hyperlipidemia has become a powerful killer that threatens people's health. Hyperlipidemia is an important factor that induces coronary heart disease, arteriosclerosis, cerebral thrombosis and fatty liver. [0003] The lipid-lowering western medicines commonly used at home and abroad mainly include: statins, phenoxyaromatic acids and other types. [0004] The statin lipid-lowering drugs are represented by simvastatin produced by Pfizer in the United States. The main effect is to reduce triglycerides, cholesterol and low-density lipoprotein cholesterol. They are currently commonly used drugs for the prevention and treatment of coronary heart disease. The common side effects of this type of drugs are...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P3/06
Inventor 胡文祥王陆瑶夏龙凤王卓
Owner BEIJING SHENZHOU XIANGRUI PHARMA SCI & TECH DEV