Glycyrrhizic acid matrine salt and glycyrrhizic acid marine salt, its preparing method and use

A technology of pyranosidonic acid matrine salt and glycyrrhizic acid, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, steroids, etc., and can solve the problem of undisclosed ratio of glycyrrhizic acid without giving therapeutic effect And other problems such as matrine complex salt, to achieve a good curative effect
CN101012267AActive Publication Date: 2007-08-08CHIA TAI TIANQING PHARMA GRP CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CHIA TAI TIANQING PHARMA GRP CO LTD
Publication Date
2007-08-08

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Abstract

The invention discloses a new synthesizing method of glycyrrhizin matrine salt and glycyrrhizin sophora flavescent salt, which also provides epimer 18-beta or 18-alpha glycyrrhizin sophora flavescent salt and their manufacturing method and application to make liver disease drug.
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Description

technical field

[0001] The present invention relates to a medicine that can be used for the treatment of liver diseases, specifically a salt formed by combining glycyrrhizic acid with matrine or matrine, and the salt is 18-alpha glycyrrhizic acid or 18-beta glycyrrhizic acid, which are different epimers of glycyrrhizic acid A salt formed by combining acid with matrine or matrine. Background technique

[0002] Glycyrrhizin (G1ycyrrhizin, GC) is an effective active ingredient extracted from licorice. Its biological activity has been extensively studied at home and abroad and has been used clinically for many years. It has anti-inflammatory, anti-allergic, anti-biological oxidation, immune function regulation, block Ca 2+ Influx, dissociation of adrenal cortex hormone and stabilization of lysosomal membrane and other pharmacological effects, among which anti-inflammatory effect is the main mechanism of glycyrrhizic acid against liver injury.

[0003] Matrine and matrine are t...

Claims

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