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Extract of polysaccharide of lithospermum erthrorhizon and composition containing same and use thereof

A technology of comfrey polysaccharide and extract, applied in the field of medicine

Inactive Publication Date: 2010-07-07
GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, it is mainly used for its anti-fertility effect; anti-inflammatory effect, anti-tumor, bactericidal anti-virus; liver protection and immune regulation, and it has also been reported that comfrey polysaccharide has anti-herpes simplex virus type I (HSV-I) effect, but in the treatment of Condyloma acuminatum (CA) caused by human papillomavirus has not been reported yet

Method used

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  • Extract of polysaccharide of lithospermum erthrorhizon and composition containing same and use thereof
  • Extract of polysaccharide of lithospermum erthrorhizon and composition containing same and use thereof
  • Extract of polysaccharide of lithospermum erthrorhizon and composition containing same and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0129] Example 1 Preparation Example of Lithospermum Polysaccharide

[0130] Take 50g of comfrey, pulverize, add 15 times the amount of water, and extract 3 times at 100°C under reflux for 1 hour each time. The extract is concentrated to 90mL, cooled, and under rapid stirring, 95% ethanol is added to make the alcohol content reach 80%, then place at room temperature for more than 24 hours, suction and filter the precipitate to obtain the alcohol precipitation product, then dissolve the precipitate in 100 mL of distilled water, heat at 60°C to fully dissolve it, centrifuge at 3000 rpm for 15 minutes, and then filter and discard To remove the precipitate, add 95% ethanol to the obtained solution to make the alcohol content reach 80%, and then leave it for more than 24 hours, and then filter with suction to obtain the second alcohol precipitation product. Combine the two alcohol precipitation products to obtain comfrey polysaccharide Extract: Add the dried comfrey polysaccharide ext...

Embodiment 2

[0131] Example 2 Preparation Example of Lithospermum Polysaccharide

[0132] Take 50g of comfrey, pulverize, add 15 times the amount of water, and extract 3 times at 100°C under reflux for 1 hour each time. The extract is concentrated to 90mL, cooled, and under rapid stirring, 95% ethanol is added to make the alcohol content reach 80%, then place at room temperature for more than 24 hours, suction and filter the precipitate to obtain the alcohol precipitation product, then dissolve the precipitate in 100 mL of distilled water, heat at 60°C to fully dissolve it, centrifuge at 3000 rpm for 15 minutes, and then filter and discard To remove the precipitate, add 95% ethanol to the obtained solution to make the alcohol content reach 80%, and then leave it for more than 24 hours, and then filter with suction to obtain the second alcohol precipitation product. Combine the two alcohol precipitation products to obtain comfrey polysaccharide Extract.

Embodiment 3

[0133] Example 3 Preparation Example of Lithospermum Polysaccharide

[0134] Take comfrey, reflux for extraction, concentrate the extract, cool it, add ethanol, settle with alcohol, stand still, suction and filter the precipitate to obtain the alcohol precipitated product, then dissolve the precipitate in water, heat to fully dissolve it, centrifuge, Then the precipitate is removed by suction filtration, ethanol is added to the obtained solution, alcohol precipitation, standing, and suction filtration to obtain the second alcohol precipitation product, and the two alcohol precipitation products are combined to obtain the comfrey polysaccharide extract.

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Abstract

The present invention provides a puccoon extract-puccoon polysaccharide and its application in preparation of medicine for effectively curing pointed condyloma. Said medicine has effective action for killing human papilloma virus, so that it can effectively cure the pointed condyloma due to human papilloma virus. Besides, said invention also provides a method for preparing said puccoon polysaccharide by using Chinese medicinal material puccoon.

Description

Technical field [0001] The present invention relates to the field of medicine, in particular to a comfrey polysaccharide extract, a composition containing the comfrey polysaccharide extract and its use. Background technique [0002] Condyloma acuminatum (CA), also known as condyloma acuminatum, or Venereal Warts, or Genital Warts, or Anogenital Warts, is a type of warts that mainly occurs in the male and female external genitals and anus Diseases of the skin and mucous membranes. Its incidence has been increasing year by year, and it has become the second place among sexually transmitted diseases in my country. Moreover, the disease has the risk of causing malignant tumors, which seriously endanger human health, so the disease has attracted more and more attention. [0003] Traditional Chinese medicine believes that condyloma acuminatum belongs to the category of "thousand-day sore", also known as "pruritus" and "pruritus". Its pathogenesis is mostly unclean intercourse or indire...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/30A61K31/715A61P15/02C08B37/00A61K125/00
Inventor 邓远辉
Owner GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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