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Method for sterilizing fermenter

A technology of disinfection and sterilization, fermentation tank, applied in heating and other directions, can solve the problems of large steam consumption, low equipment utilization rate, long non-production time, etc., to save energy, reduce time and labor of workers, and ensure aseptic effect Effect

Inactive Publication Date: 2007-09-05
LINGHUA GROUP INCORPORATED COMPANY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] In the traditional fermentation process, such as glutamic acid, glutamine, lysine and other fermentation products, in order to ensure the smooth progress of the fermentation process and eliminate the contamination and economic losses caused by equipment, the continuous disinfection and sterilization method of fermentation broth is required The fermenter is cleaned with lye before each batch of feed, and then sterilized by steam and high pressure. This disinfection method not only consumes a lot of steam, but also has a lot of non-production time for the equipment, and the utilization rate of the equipment is low.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Embodiment 1: The fermentation tank sterilization method, in the case of continuous disinfection and sterilization of the fermented liquid, changes the disinfection mode of the fermentation tank, reduces the number of steam disinfection tanks, saves steam, and steams the fermentation tank after multiple batches of fermentation. Bacteria once, that is, each batch of fermentation tanks is only fed with lye (100°C, 25 minutes) for cyclic cleaning, and after three batches of operation, steam is used for high-pressure sterilization (120°C, 0.20MPa, 40 minutes), also reached the original effect of disinfection and sterilization of each batch of fermentation tanks. The operation process of the present invention is: end of fermentation → disinfection of fermenter (100°C, 25 minutes for each batch of lye) for cyclic cleaning, every 3 batches of high-pressure steam sterilization (120°C, 0.20MPa, 40 minutes) → Feeding→fermentation.

Embodiment 2

[0009] Embodiment 2: The fermenter sterilization method, in the case of continuous sterilization of the fermented liquid, changes the sterilization method of the fermenter, reduces the number of times of steam sterilization, saves steam, and steams the fermenter once after multiple batches of fermentation The method, that is, each batch of fermentation tanks is only fed with lye (105°C, 20 minutes) for circular cleaning, and then steam is used for high-pressure sterilization (125°C, 0.18MPa, 35 minutes) after 4 batches of operation ), also reach the original effect of disinfection and sterilization of each batch of fermentation tanks. The operation process of the present invention is: end of fermentation → disinfection of fermenter (each batch of lye 105°C, 20 minutes) for circular cleaning, every 4 batches of high-pressure steam sterilization (125°C, 0.18MPa, 35 minutes) → Feeding→fermentation.

Embodiment 3

[0010] Embodiment 3: The fermenter sterilization method, in the case of continuous sterilization of the fermented liquid, changes the sterilization method of the fermenter, reduces the number of times of steam sterilization, saves steam, and steams the fermenter once after multiple batches of fermentation The method, that is, each batch of fermentation tanks is only fed with lye (95°C, 30 minutes) for circular cleaning, and then steam is used for high-pressure sterilization (122°C, 0.22MPa, 45 minutes) after 5 batches of operation ), also reach the original effect of disinfection and sterilization of each batch of fermentation tanks. The operation process of the present invention is: end of fermentation → sterilization of fermenter (each batch of lye 95°C, 30 minutes) for circular cleaning, every 5 batches of high-pressure steam sterilization (122°C, 0.22MPa, 45 minutes) → Feeding→fermentation.

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Abstract

A method for disinfecting and sterilizing the fermentation tank features that the fermentation tank is disinfected and sterilized by steam at 120-125 deg.C under 0.18-0.22 MPa for 35-45 min after it is washed periodically by alkali solution at 95-105 deg.C for 20-30 min 3-5 times. Its advantages are less consumption of steam and high productivity.

Description

(1) Technical field [0001] The invention relates to a disinfection and sterilization technology, in particular to a new method for disinfection and sterilization of fermenters in use. (2) Technical background [0002] In the traditional fermentation process, such as glutamic acid, glutamine, lysine and other fermentation products, in order to ensure the smooth progress of the fermentation process and eliminate the contamination and economic losses caused by equipment, the continuous disinfection and sterilization method of fermentation broth is required The fermenter is cleaned with lye before feeding each batch, and then sterilized by steam and high pressure. This sterilization method not only consumes a lot of steam, but also has more non-production time of the equipment, and the utilization rate of the equipment is low. (3) Contents of the invention [0003] The technical task of the present invention is to provide a fermentation tank disinfection and sterilization meth...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L2/07
Inventor 杨玉岭岳希金邵明金满德恩胡昆之马志刚
Owner LINGHUA GROUP INCORPORATED COMPANY
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