Tripterygium glycosides extract and its extraction process
A technology of tripterygium glycosides and extraction methods, which is applied in the field of plant extracts and its extraction, can solve problems such as poor product quality, low content of medicinal components of tripterygium glycosides, and difficult large-scale industrial production of the process, and achieve Improve the separation effect, facilitate large-scale industrial operation, and have high industrial application value
Active Publication Date: 2010-08-18
江苏美通制药有限公司 +1
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Problems solved by technology
The technical problem to be solved by the present invention is to overcome the problems of low content of medicinal ingredients in tripterygium wilfordii polyglycosides extracted by the extraction method of the prior art, poor product quality, or difficult large-scale industrial production of the process, and provide a product High efficacy ingredients, good pharmacological effect, easy operation, low cost, short production cycle, less environmental pollution, easy to apply to large-scale industrial production of tripterygium glycosides extraction method, and its tripterygium glycosides products
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Abstract
The process of extracting tripterygium glycosides includes the following steps: 1. extracting coarse tripterygium glycosides product through water extracting tripterygium powder, extracting with alcohol or alcohol aqua, merging the extracted solution, concentrating to volume content of alcohol not more than 20 %, organic solvent extracting and concentrating to obtain dry coarse tripterygium glycosides product; and 2. refining through dissolving the coarse product in organic solvent, adsorbing with adsorbent, filtering, eluting the filter cake, concentrating the eluted liquid, column chromatographic separation, eluting with organic solvent, and concentrating the eluted liquid to obtain dry product. The process has simple operation, low cost, short production period, less environmental pollution, and easy application in industrial production, and the product has high effective component content and high pharmaceutical effect.
Description
technical field The invention relates to a plant extract and an extracting method thereof, in particular to a tripterygium glycoside extract and an extracting method thereof. Background technique Tripterygium genus is mainly distributed in the mountainous area south of the Yangtze River Basin and Changbai Mountain in northeast China in my country. It is widely spread among the people as herbal medicine for treating arthritis, bruises, skin diseases, etc., and is also used as pesticide. Clinically, domestic research on Tripterygium wilfordii has achieved remarkable results and breakthroughs. It has developed from the treatment of rheumatoid arthritis to the treatment of lupus erythematosus, psoriasis, nephritis and tumor research and other common diseases and difficult miscellaneous diseases. Due to its It has a wide range of applications, remarkable curative effect, and has a unique therapeutic effect on difficult and persistent diseases, so it has gradually become a focus o...
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/37A61P13/12
Inventor 林健
Owner 江苏美通制药有限公司
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