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Treatment method for reducing the content of heavy metals and pesticide residues in Chinese medicinal materials

A processing method and technology of Chinese herbal medicines, which are applied in the direction of medical formulas, plant raw materials, and medical raw materials derived from Ginkgo biloba, etc., which can solve the problem of reduced drug efficacy, inability to rule out adverse reactions, increase of Chinese herbal medicine extracts, and potential safety hazards of extract medication And other issues

Active Publication Date: 2022-03-15
CHENGDU LONGQUAN HIGH TECH NATURAL PHARMLCO
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the reaction reagents are basically chemical agents, their medication safety risks are great
At the same time, in view of the complexity of the components in the extract of traditional Chinese medicine, the possibility of adverse reactions between the treatment reagents and the components of the extract cannot be ruled out under the circumstances that the existing cognitive ability and technical means cannot be fully grasped, thus further increasing the Potential drug safety hazards of Chinese herbal medicine extracts and extracts obtained by this treatment method
In the material adsorption type treatment method, the adsorption material uses chemical and physical methods to adsorb heavy metal ions. Although it avoids the problem of reagent retention in the reagent reaction type treatment technical scheme, it cannot be ruled out due to the limitations of existing cognitive ability and technical means. Its adsorption of active ingredients in Chinese herbal extracts or extracts, resulting in a reduction in efficacy

Method used

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  • Treatment method for reducing the content of heavy metals and pesticide residues in Chinese medicinal materials
  • Treatment method for reducing the content of heavy metals and pesticide residues in Chinese medicinal materials
  • Treatment method for reducing the content of heavy metals and pesticide residues in Chinese medicinal materials

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Taking Suhe Decoction Jiawei II as an example, its formula includes: honeysuckle, forsythia, red lily, scrophulariaceae, Smilax smilax, Dipsacus, ginkgo leaf and other medicinal materials.

[0046] The above-mentioned medicinal materials are respectively processed as follows:

[0047] 1. Manual selection one by one, and stripping off the surface impurities;

[0048] 2. Air separation machine air separation to remove impurities;

[0049] 3. Random inspection to ensure that there are no visible impurities on the surface of medicinal materials;

[0050] 4. According to the production plan, weigh a specific amount of medicinal materials that have been dry sorted and removed;

[0051] 5. Move the weighed medicinal materials into the rinsing tank, spray and rinse with drinking water at room temperature until the water is clean;

[0052] 6. According to the amount of medicinal materials in the rinsing tank, use food-grade baking soda and room temperature drinking water to p...

Embodiment 2

[0060] Taking the bone fracture oral prescription as an example, the formula includes: angelica tail, chuanxiong, myrrh, safflower, cassia twig tip, notoginseng, earthworm, epimedium, medlar, woody, licorice, drynaria and other medicinal materials.

[0061] The above-mentioned medicinal materials are respectively processed as follows:

[0062] 1. Manual selection one by one, and stripping off the surface impurities;

[0063] 2. Air separation machine air separation to remove impurities;

[0064] 3. Random inspection to ensure that there are no visible impurities on the surface of medicinal materials;

[0065] 4. According to the production plan, weigh a specific amount of medicinal materials that have been dry sorted and removed;

[0066] 5. Move the weighed medicinal materials into the rinsing tank, spray and rinse with drinking water at room temperature until the water is clean;

[0067] 6. According to the amount of medicinal materials in the rinsing tank, use food-grade...

Embodiment 3

[0075] Taking Linglong Killing Ghost Pill as an example, its formula includes: licorice, ghost arrow feather, gardenia, scutellaria baicalensis, berberine, phellodendron, cooked rhubarb and other medicinal materials.

[0076] The above-mentioned medicinal materials are respectively processed as follows:

[0077] 1. Manual selection one by one, and stripping off the surface impurities;

[0078] 2. Manually operate the dedusting air gun to blow and dedust the selected medicinal materials one by one to ensure that there are no visible impurities on the surface;

[0079] 3. According to the production plan, weigh a certain amount of medicinal materials that have been dry sorted and removed;

[0080] 4. Move the weighed medicinal materials into the rinse tank, spray and rinse with drinking water at room temperature until the water is clean;

[0081] 5. According to the amount of medicinal materials in the rinsing tank, use food-grade baking soda and room temperature drinking wate...

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Abstract

The invention provides a treatment method for reducing the content of heavy metals and pesticide residues in traditional Chinese medicinal materials. The steps of dry sorting, impurity removal, drinking water flushing, food-grade alkaline solvent moistening, and warm hot water flushing are successively performed on the medicinal materials. Thoroughly remove impurities such as sediment rich in heavy metals and pesticide residues on the surface, and use the metabolic function of the medicinal materials to promote the efflux of harmful components such as heavy metals and pesticide residues in the medicinal materials. The degree of intervention and extremely high food safety make the heavy metal and pesticide residue content in the final product produced by using the above-mentioned treated medicinal materials meet the requirements of the US Pharmacopoeia Herbal Drugs Division.

Description

technical field [0001] The invention relates to the technical field of production of Chinese medicinal materials, in particular to a treatment method for reducing the content of heavy metals and pesticide residues in Chinese medicinal materials. Background technique [0002] In the revised opinion draft of the 2020 version of "0212 General Rules for the Testing of Medicinal Materials and Decoction Pieces", the State Pharmacopoeia Commission plans to conduct a comprehensive inspection of the limits of heavy metals and harmful elements (lead, cadmium, arsenic, mercury, copper) on plant-based Chinese medicinal materials. And 33 pesticides were included in the banned list. Since traditional Chinese medicinal materials are agricultural and sideline products first, their planting management is not significantly different from other agricultural products produced by planting methods. Therefore, growers must implement pest and disease protection measures to ensure production. Due t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/90A61K36/8967A61K36/815A61K36/756A61K36/9068
CPCA61K36/355A61K36/634A61K36/8967A61K36/808A61K36/90A61K36/896A61K36/185A61K36/16A61K36/232A61K36/236A61K36/328A61K36/286A61K36/54A61K36/258A61K35/62A61K36/296A61K36/815A61K36/285A61K36/484A61K36/126A61K36/37A61K36/744A61K36/539A61K36/718A61K36/756A61K36/708A61K36/488A61K36/71A61K36/65A61K36/9068A61K36/79A61K36/57A61K36/346A61K36/899A61K36/42A61K36/9064A61K36/888A61K36/754A61K36/725A61K36/344A61K36/537A61K36/515A61K2236/13A61K2300/00
Inventor 李益龚靖
Owner CHENGDU LONGQUAN HIGH TECH NATURAL PHARMLCO
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