Streptococcus faecium function signal molecule formulation and product thereof for reducing fat and slimming

Abstract

The invention relates to a streptococcus faecium function signal molecule preparation, a streptococcus faecium bacteria strain is carried out the anaerobic fermentation at 35 to 38 DEG C and the centrifugal concentration to obtain a concentrate of streptococcus faecium bacteria, the bacterial cell wall is broken by high pressure, and the freeze-drying is carried out to obtain the preparation raw powder containing the streptococcus faecium function signal molecules. As the streptococcus faecium function signal molecules can be combined with a specific receptor at the intestinal epithelial cells, the issued signal can induce the excessive cholesterol in the body to carry out the transformation, control the activity of the cholesterol synthase, reduce the excessive cholesterol generated or absorbed in the human body, and effectively control the obesity. The streptococcus faecium function signal molecule preparation is simultaneously matched with a bifidobacterium function signal molecule preparation, a lactobacillus function signal molecule preparation and a bacteroides function signal molecule preparation to be prepared into a series of products containing various probiotics function signal molecules for lipid-lowering and weight-losing, thus fundamentally reducing the risks of coronary heart disease, atherosclerosis, heart diseases, angina, myocardial infarction, obesity and other diseases during the process of being eaten by the people.

Description

technical field [0001] The present invention relates to the field of pharmaceutical preparations derived from microbial materials, in particular pharmaceutical preparations derived from bacteria. Background technique [0002] According to the data of the fourth Chinese Resident Nutrition and Health Survey jointly released by the Ministry of Health, the Ministry of Science and Technology and the National Bureau of Statistics, the number of people with hypertension and dyslipidemia in the country has reached 160 million; the number of people with diabetes has ranked first in the world , reaching 23.8 million; the number of overweight and obese totaled 260 million. To make matters worse, the incidence of these diseases is increasing rapidly, and there is a phenomenon of rejuvenation [1]. Over the past ten years, the prevalence of hypertension among residents aged 16 and over in my country has increased by 31%, and the obesity rate has increased by 97%. A survey funded by the ...

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Problems solved by technology

The second is that patients who take broad-spectrum antibiotics for a long time can produce drug-resistant strains in the body, and the body's cellular immunity and humoral immunity will decline, especially the microecological imbalance in the intestinal tract, the beneficial bacteria in the intestine will be inhibited, and the ability to reduce cholesterol will decrease, resulting in Increased cholesterol levels in the body [10, 11]

Although the second-generation product avoids the two bottlenecks of the number of viable bacteria and the survival period, it also has a fatal shortcoming, which is that the dead bacteria are difficult to quantify, which is not conducive to quality control, and it is actually difficult to become a qualified product.

[0006] At present, there are few reports on probiotic functional signaling molecule (PSM) preparations, but there has never been any report on the use of probiotic functional signaling molecule (PSM) as a lipid-lowering and weight-loss product

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