57results about How to "Increase route of administration" patented technology

The invention belongs to the technical field of traditional Chinese medicine preparations for beasts, and particularly relates to a traditional Chinese medicine preparation for preventing weaned piglets from suffering diarrhea, and a preparation method of the traditional Chinese medicine preparation. The traditional Chinese medicine preparation is mainly prepared from the following raw materials in parts by weight: plant extracts and glucose, wherein the plant extracts comprise dandelion extracts, astragalus membranaceus extracts, herba andrographitis extracts, and cordate houttuynia extracts. The preparation method of the medicine preparation comprises the following steps: sieving the plant extracts with a sieve of 50-70 meshes, uniformly mixing the sieved plant extracts, adding the glucose sieved by a sieve of 70-100 meshes in the mixed plant extracts, and uniformly mixing the sieved glucose with the mixed plant extracts so as to obtain the traditional Chinese medicine preparation. The traditional Chinese medicine preparation for preventing weaned piglets from suffering, disclosed by the invention, has significant effects of resisting bacteria and resisting viruses, and can significantly reinforce the immunity of weaned piglets; the traditional Chinese medicine preparation is rich in nutritional substances, so that the nutritional needs of weaned piglets can be met; the traditional Chinese medicine preparation has the advantages that the gastroenteric functions of weaned piglets can be regulated, the absorption of nutritional substances can be promoted, the daily gain of weaned piglets can be increased, and the feed converting rate can be increased, so that the phenomenon that the weaned piglets are liable to get diarrhea is effectively avoided.

This invention supplies a method for preparing nanorealgar colloid and nanorealgar through modulating their appearance and particle size with biology macromolecular mold. Its characteristic is: chemically remove arsenic and impurity elements from natural realgar mine, make nanorealgar colloid and nanorealgar by taking biology macromolecular as mold to modulate the appearance and particle size, so nanorealgars of various appearance and particle size can be prepared by changing mold varieties and ageing conditions. This invention has broad processing raw materials, and the yielded nanorealgar has high purity, uniform particle size, good water-solubility, it is uneasy to oxidation or reunion and has obverse synergism effect with mold molecule. It can markedly strengthen the effect of realgar antibiosis and anti-tumour, improve realgar biology availability, depress realgar toxic side effect and expand realgar route of administration.

The invention relates to solid lipid nanoparticles of daidzein which is a hydrophobic medicine and a preparation method thereof. The average particle size of the solid lipid nanoparticles of daidzein is less than 100 nanometers; and based on weight part, the solid lipid nanoparticles comprise 1 part of daidzein, 5 to 30 parts of phospholipid, 1 to 50 parts of surfactant and 1 to 40 parts of solidlipid material, wherein the daidzein and phospholipid form a composite which is covered by solid lipid or the solid lipid and phospholipid. The daidzein solid lipid nanoparticles are prepared by a thin-film dispersion method or hot-melt dispersion method. The preparation method comprises: forming a composite of the daidzein and phospholipid; and covering the composite with the solid lipid nanoparticles for solving the problems of low solubility, low stability and preparation difficulty in preparation process of the daidzein. The average particle size of the solid lipid nanoparticles is less than 100 nanometers, and the rate of in-vitro release in 8 hours reaches 58.4 percent, and the oral bioavailability is high; and the solid lipid nanoparticles can be further prepared into capsules, oral suspension, oral liquid and other oral preparation, and can make the medicine taken by the patient easily.

The invention belongs to the field of bio-medicines, and particularly relates to an application of a hemopoietin sourced peptide in preparation of a medicine for treating the metabolic syndrome. The application includes an application of preparation of medicines for treating obesity, diabetes mellitus and hyperlipemia, The hemopoietin sourced peptide can be prepared into lipidosome, and the metabolic syndrome can be treated by the hemopoietin sourced peptide and the hemopoietin sourced peptide lipidosome, the syndromes of the hemopoietin sourced peptide are remarkably relieved after treatment, and the effect of the hemopoietin sourced peptide lipidosome is superior to that of the hemopoietin sourced peptide, and the administration frequency can be reduced. The application of the hemopoietin sourced peptide lipidosome to medicines can be used for prolonging the medicine acting period, increasing the lipid solubility and stability of the medicines and reducing toxic and side effects. Therefore, compared with an independent application of micro-molecule polypeptide, lipidosome coated micro-molecule polypeptide has the advantages of prolonging half-life period, improving stability and lipid solubility and increasing administration routes. The hemopoietin sourced peptide has an important clinical application value.

The invention relates to a cinnamomum longepaniculatum leaf volatile oil beta-cyclodextrin clathrate compound serving as a functional biological feed additive and a preparation method thereof. The preparation method comprises the following steps of: adding cinnamomum longepaniculatum leaf volatile oil dissolved in an organic solvent into aqueous solution containing beta-cyclodextrin, and stirring. The cinnamomum longepaniculatum leaf volatile oil beta-cyclodextrin clathrate compound has the characteristics of mild clathrate condition, simplicity of operation, easy control and high clathrate yield. The prepared clathrate compound makes the cinnamomum longepaniculatum leaf volatile oil in the solid state and convenient to mix for livestock and poultry, the medicinal effect of the volatile oil can be protected, and the palatability is improved, so the defects of irritation, volatility and the like due to the direct adoption of the volatile oil are overcome. The clathrate compound has theeffects of resisting bacteria (escherichia coli, salmonella and staphylococcus aureus), resisting fungi (trichophyton mentagrophytes, microsporum canis and microsporum gypseum), killing insect pests,easing pain and resisting inflammation, and is a good biological feed additive which is used for resisting diseases and promoting growth and avoids residue.