Use of garlic oil in preparing medicine against acute alcoholic fatty liver

A technology of alcoholic fatty liver and garlic oil, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems that have no anti-acute alcoholic fatty liver effect and so on

Active Publication Date: 2008-11-19
山东淄博新达制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

There are many reports at home and abroad that garlic has the functions of anti-cancer, lowering blood pressure, lowering blood ...

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  • Use of garlic oil in preparing medicine against acute alcoholic fatty liver
  • Use of garlic oil in preparing medicine against acute alcoholic fatty liver
  • Use of garlic oil in preparing medicine against acute alcoholic fatty liver

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Abstract

The invention discloses the new use of garlic oil, namely the application of the garlic oil in preparing the medicaments used for resist acute alcoholic fatty liver. 50 to 200 mg of garlic oil is contained in the medicaments resisting acute alcoholic fatty liver caused by alcohol of 4.8g/kg.bw per kilogram of body. The garlic oil is taken orally, and is taken two hours prior to drinking. Before the garlic oil is taken, the garlic oil can be diluted with corn oil. Proven through experiments on mice, the garlic oil can significantly reduce the liver index, sera TG, liver TG, and inhibit liver MDA l from rising caused by ethano, and can increase the content of GSH in the liver, which has the function of resisting acute alcoholic fatty liver. The garlic oil can be used for preparing medicaments for resisting acute alcoholic fatty liver, and establishes a new application way for preventing alcoholic hepatopathy.

Description

technical field The invention relates to a new application of garlic oil, in particular to the application of garlic oil in the preparation of anti-acute alcoholic fatty liver medicine. Background technique Garlic (allium sativum L.) is the bulb of garlic, a plant of the genus Allium in the Liliaceae family. Traditional Chinese medicine believes that garlic has the effects of stagnant qi, warming the spleen and stomach, eliminating blood stasis, detoxifying and killing insects. Sores, snake bites. Garlic oil is an oily substance extracted from garlic, which contains various sulfur-containing functional components such as allicin, ajoene and allitridin. Garlic's antibacterial and anti-inflammatory, insecticidal, anti-cancer, lowering blood pressure, lowering blood fat, preventing atherosclerosis, and regulating immune function are all related to garlic oil. There are many reports at home and abroad that garlic has the functions of anti-cancer, lowering blood pressure, lowe...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P1/16A61K125/00
Inventor 谢克勤曾涛张翠丽赵秀兰于丽华宋富永
Owner 山东淄博新达制药有限公司
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