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33 results about "Ajoene" patented technology

Ajoene /ˈɑːhoʊ.iːn/ is an organosulfur compound found in garlic (Allium sativum) extracts. It is a colorless liquid that contains sulfoxide and disulfide functional groups. The name (and pronunciation) is derived from "ajo", the Spanish word for garlic. It is found as a mixture of up to four stereoisomers, which differ in terms of the stereochemistry of the central alkene (E- vs Z-) and the chirality of the sulfoxide sulfur (R- vs S-).

Use of extracts and compounds of allium-genus plants as preservatives in the food and agri-food industries

The present invention relates to the use of extracts and compounds of plants from the Allium genus for the food and agrifood industry consisting of being used as food preservatives for humans and animals, plants being harvested or post-harvest plants, as well as for environmental disinfection, using thiosulfinates, thiosulfonates, ajoene, vinyl dithiins and products resulting from the decomposition of thiosulfinates.
Owner:MOUSALA

Preparation process of ajoene

The invention relates to a preparation process of ajoene, comprising the steps of: converting natural alliin or synthesized alliin into allicin in a water solution by utilizing alliinase in garlic, adding a water-soluble organic solvent, such as alcohol, ketone, ether and the like, to remove partial impurities so as to prepare an allicin solution, then adding a dehydrating agent for moderate dehydration, converting 90% of allicin into the ajoene at moderate temperature, and evaporating the solvent to obtain an ajoene product with the purity of 90%. The process is easy to operate and is suitable to scale preparation of the ajoene products.
Owner:GUANGZHOU GENERAL HOSPITAL OF GUANGZHOU MILITARY COMMAND +1

Process for the manufacture of ajoene derivatives

InactiveUS20140303070A1Product yield is lowTime-consume and expensive purification procedureAntibacterial agentsRespiratorsCombinatorial chemistrySolvent
The present invention relates to the compound (E,Z)-ajoene of formula (1) for use in treatment of bacterial infections. Another aspect of the present invention is a composition comprising (E,Z)-ajoene of formula (1) and at least one antibiotic. Yet another aspect of the invention relates to a method for manufacturing (E,Z) ajoene of formula (1) wherein the conformation of the internal C═C— bond can be either E or Z or a mixture thereof, said method comprising reacting allicin of formula (3) with an acid in the presence of a solvent to provide (E,Z ajoene) of formula (1) as defined above. Yet another aspect of the invention is (E,Z)-ajoene of formula 1 obtainable by the method described above.
Owner:DANMARKS TEKNISKE UNIV

Ajoene microcapsule powder product and its preparation method and use

The invention provides an ajoene microcapsule powder product and its preparation method and use. The ajoene microcapsule powder product can be processed to form a plurality of dosage forms so that an application range is widened and properties and stability are good. The preparation method comprises carrying out extraction on garlicin-containing raw materials through water, filtering the extract to obtain a garlicin aqueous solution, extracting garlicin in the garlicin aqueous solution through an organic solvent, collecting the organic solvent phase, removing water, drying the garlicin to obtain garlicin-containing garlic oil, preparing a beta-cyclodextrin aqueous solution, embedding the garlicin-containing garlic oil with the beta-cyclodextrin aqueous solution to obtain a beta-cyclodextrin suspension, drying and crushing the beta-cyclodextrin suspension, and sieving the powder to obtain the ajoene microcapsule powder product. The preparation method can be used for ajoene microcapsule powder product preparation.
Owner:青岛博恩高科生物技术有限公司

Single particle nano-garlicin micro-capsule, and its preparation method

A single-particle nano-allicin microcapsule, which is composed of a single-particle garlic active ingredient and a wall material embedded outside it, the wall material is N-LOK modified starch or β-CD, and the active ingredients include allicin, allicin, Ajoene, Selenium and Germanium. Preparation steps: put the washed and purified garlic raw material in a container, then add ethanol, dichloromethane or water solvent with a concentration of 70-100%, put it into a multi-dimensional microwave environment for multi-dimensional microwave-induced extraction, and the extraction temperature is 40-50°C , the extraction pressure is 0.06-0.12Mpa, and its active ingredients are extracted into the solvent; after being filtered, it is sent to the concentration tank for concentration under reduced pressure to obtain a mixed extract containing the active ingredients of garlic; the active ingredients are obtained by condensation; the concentrated solution is added N-LOK modified starch or β-CD, stirred at low temperature to make a mixture liquid, and then sent to the ring-shaped nano-jet atomizer for atomization and drying, so as to obtain single-particle nano-garlicin microcapsules and make them into powder, tablets or Capsule dosage form; it has the advantages of high extraction rate and basically no damage to plant active ingredients.
Owner:INSITUTE OF BIOPHYSICS CHINESE ACADEMY OF SCIENCES +1
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