Emulsion type gel preparation containing chlorhexidine and alcohol

Abstract

The invention relates to an emulsion type gel preparation containing chlorhexidine and ethanol. The emulsion type gel preparation containing chlorhexidine and ethanol comprises the following components by weight percentage: 0.5 to 5 of the chlorhexidine; 30 to 70 of the ethanol; 3 to 10 of stearic acid; 2 to 5 of white petrolatum; 0.5 to 3 of lanoline; 0.5 to 2 of triethanolamine; 1 to 5 of glycerin; 0.1 to 1 of xanthan gum; allowance of water. The stearic acid, the white petrolatum and the lanoline are heated to 70 DEG C to 80 DEG C and mixed evenly, thus obtaining solution A; the chlorhexidine, the triethanolamine, the glycerin, the xanthan gum and the water are heated to 70 DEG C to 80 DEG C, stirred and dissolved, thus obtaining solution B; when stirring, the solution A is added to the solution B slowly when the solution is hot, stirred continuously until the temperature is reduced to 50 DEG C to 60 DEG C naturally; the ethanol is added and stirred for 1 hour to 2 hours, thus obtaining the emulsion type gel preparation. The emulsion type gel preparation has stable property, fast evaporation speed after being used, high moisture retention and no obvious viscosity to skin and good use feeling.

Description

technical field [0001] The present invention relates to an emulsion type gel preparation containing chlorhexidine and ethanol, which contains chlorhexidine and ethanol with disinfection effect, has stable properties, fast volatilization speed after use, and has high moisture retention to skin There is no obvious sticky feeling, and the feeling of use is good. Background technique [0002] Hand disinfection has always been an important part of hospital infection control management. If medical staff do not wash or disinfect their hands adequately after nursing activities, it is easy to cause the germs on their hands to spread to the next patient. In order to improve the effect of hand disinfection, some hand disinfectants with good disinfection effect, rapid action, convenient use, and harmless and non-irritating to the skin are needed clinically. Chlorhexidine and ethanol are widely used in skin disinfection, hygienic hand disinfection and surgical hand disinfection in curr...

AI Technical Summary

Problems solved by technology

[0005] At present, most of the disinfection products containing chlorhexidine or ethanol commonly used in the market are solution dosage forms. Since chlorhexidine and ethanol are obviously irritating to the skin, even if a specific skin care agent is added, it still produces a very uncomfortable feeling after use. Even cause skin dryness and allergies

In the clinical hand disinfection process, the solution-type products are easy to spill when they are taken by hand, which is very inconvenient to operate, and it is easy to affect the disinfection effect due to uneven rubbing