Medicine for treating postnasal catarrh and its preparation method

A technology for nasopharyngitis and medicine, applied in the field of traditional Chinese medicine, can solve the problems of insufficient treatment of hypersecretion, low curative effect and high blood cholesterol, and achieve the effects of low cost, good curative effect and simple process

Inactive Publication Date: 2009-01-07
GUANGZHOU BAIYUNSHAN QIXING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine uses Nasopharyngeal Tablets, Biyankang Tablets, Bishufu Tablets, Nasinusyan Oral Liquid, Keganliyan Oral Liquid, Huodan Pills, etc., but their efficacy is also not high, and there are certain side effects, such as traditional Chinese medicine Huodan pills contain pig gall powder, long-term use can easily lead to high blood cholesterol, etc.
In addition, these drugs are not significant enough for the treatment of hypersecretion after radiotherapy for nasopharyngeal carcinoma

Method used

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  • Medicine for treating postnasal catarrh and its preparation method
  • Medicine for treating postnasal catarrh and its preparation method
  • Medicine for treating postnasal catarrh and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The preparation of embodiment 1 granule

[0031] The composition of each bulk drug is:

[0032] Wild chrysanthemum 390g Xanthium 390g Snake bubble tendon 390g Chonglou 390g

[0033] Liangmianzhen 195g, Prunella vulgaris 195g, Gentiana 117g, Codonopsis 117g

[0034] The above eight flavors are decocted twice with water, the first time is 2 hours, the second time is 1 hour, filtered, the filtrate is combined, concentrated to a thick paste with a relative density of 1.15-1.17 (measured at 70-80°C), and ethanol is added to make it The alcohol content reaches 60% by volume, let it stand still to precipitate, take the supernatant to reclaim ethanol to obtain a concentrated solution, add an appropriate amount of 60% alcohol to the precipitate, let stand to precipitate, take the supernatant to reclaim ethanol and mix and concentrate with the above-mentioned concentrated solution to Appropriate amount, add appropriate amount of sucrose powder, make granules, dry, make 1000g, a...

Embodiment 2

[0036] The preparation of embodiment 2 capsules

[0037] The composition of each bulk drug is:

[0038] Wild chrysanthemum 300g Xanthium 500g Snake bubble tendon 1000g Chonglou 200g

[0039] LMZ 150g, Prunella vulgaris 250g, Gentiana 300g, Dangshen 60g

[0040] 1) Take the above eight-flavored raw materials, add water to immerse and decoct 1-3 times, filter, combine the filtrates, and concentrate to a thick paste with a relative density of 1.15-1.17 (measured at 70-80°C);

[0041] 2) Add ethanol until the alcohol content reaches 40% by volume, let stand to precipitate, take the supernatant and recycle the ethanol to obtain a concentrated solution, add an appropriate amount of 40% by volume ethanol to the precipitate, stir and let stand to precipitate, and take the supernatant Recover ethanol, combine the secondary concentrated solution, and further concentrate into a thick paste;

[0042] 3) Add an appropriate amount of microcrystalline cellulose to the thick paste and dry ...

Embodiment 3

[0044] The preparation of embodiment 3 capsules

[0045] The composition of each bulk drug is:

[0046] Wild chrysanthemum 1000g Cocklebur 300g Snake bubble tendon 500g Chonglou 400g

[0047] LMZ 300g, Prunella vulgaris 150g, Gentiana 250g, Dangshen 300g

[0048] Change the microcrystalline cellulose in step 3) to dextrin, change the glidant talc powder in step 4) to magnesium stearate, and the rest of the preparation method is the same as in Example 2.

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Abstract

The invention provides a medicament for curing chronic nasopharyngitis, and the preparation method thereof. The medicament is a medicament for oral administration, which is prepared from the following eight crude drugs: wild chrysanthemum flower, cocklebur fruit, red raspberry, paris polyphylla, shinyleaf pricklyash root, common selfheal fruit-spike, radix gentianae and radix codonopsitis. The preparation method comprises the following steps: aqueous-extracting and alcohol-depositing, concentrating the alcohol soluble extract and preparing into a thick paste, adding sucrose powder and further preparing into granules, or optionally preparing into other preparations for oral administration. The medicament has the effects of clearing heat, detoxifying, reducing phlegm and eliminating stagnation, and is applicable in curing nasopharyngitis caused by accumulation of toxic heat, nasopharyngeal gall, nasopharyngeal chronic inflammation and secretion increase after the radiation therapy of the nasopharyngeal carcinoma. The clinical trial shows that the medicament has good curative effect on the nasopharyngitis-related diseases without any obvious toxic or side effect and adverse reactions. The preparation method has the advantages of simple and scientific process, low cost and no pollution.

Description

technical field [0001] The invention relates to a medicine for treating chronic nasopharyngitis and a preparation method thereof, which has the functions of clearing heat and detoxifying, resolving phlegm and dispelling stagnation, and belongs to the field of traditional Chinese medicines. Background technique [0002] Chronic nasopharyngitis is a common disease in the ENT department, and the pathological changes are mainly inflammation of the nasopharyngeal mucosa and submucosal tissue. Clinically, its symptoms are diverse, such as nasal congestion, phlegm, dry mouth, sore throat, dizziness, headache, discomfort swallowing, etc. At the same time, it can cause complications in the nasal cavity, sinuses, inner ear, tear duct, and throat. The combination of Fuma solution, acetylspiramycin, and cetirizine tablets can have the effects of antibacterial, antiallergic, reducing mucosal edema, and promoting smooth secretion of mucosal glands, so that nasopharyngitis disappears or im...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/16A61K9/20A61K9/28A61P11/02A61P11/04
Inventor 刘声波黄夏敏邓祝玲颜美婷彭中芳蒋文庆於美鸿梁绍河
Owner GUANGZHOU BAIYUNSHAN QIXING PHARMA
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