Medicament composition for preventing and controlling acne

A composition and drug technology, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of long medication time, cure rate, marked effect, overall unsatisfactory curative effect, high recurrence rate, etc.

Inactive Publication Date: 2009-01-14
王士学
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A variety of drugs and physical therapy methods have certain effects on acne, but the overall curative effect such as cure rate and marked efficiency is not satisfactory; some use methods are cumbersome, and the medication time is very long; there are also common defects such as high recurrence rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Silver flower 550 grams Angelica dahurica 400 grams Scutellaria baicalensis 300 grams Honeysuckle 500 grams Rhubarb 400 grams Aloe vera 300 grams

[0024] Break the above medicines into coarse grains (3-5 mesh), add 5 times the amount of cold water to soak for 48 hours, filter the extract to get the filtrate. Add 3 times the amount of cold water to the filter residue, soak for 24 hours, and filter again to obtain the filtrate. Combine the two filtrates for evaporation and concentration, add ethanol after cooling and place at low temperature for 48 hours, filter the mixture and evaporate and concentrate the filtrate again to obtain a brown viscous extract. At this time, the weight loss on drying of the extract is below 35 parts. The extract was concentrated and dried again to generate crude crystals for future use.

Embodiment 2

[0026] Silver flower 850 grams Angelica dahurica 450 grams Scutellaria baicalensis 360 grams Honeysuckle 480 grams Rhubarb 450 grams Aloe vera 420 grams

[0027] Crush the above medicines into coarse particles (3-5 mesh), add 5 times the amount of clear water to soak for 4 hours, then heat with steam at 80-90°C for 4 hours, filter to get the filtrate. Add 3 times the amount of clear water to the filter residue, heat it with steam at 80-90°C for 2 hours, and filter again to obtain the filtrate. The two filtrates were combined and concentrated by evaporation. After cooling, ethanol was added and placed at low temperature for 48 hours. The mixture was filtered and the filtrate was evaporated and concentrated again to obtain a brown viscous extract. At this time, the weight loss on drying of the extract was below 35 parts. After extraction, concentration and drying again, crude crystals are formed, and then the crude crystals are recrystallized in dilute ethanol solution to obtain...

Embodiment 3

[0028] Embodiment 3 prepares ointment

[0029] Prescription: 10 grams of crystallization of medicine prepared by embodiment 1 20 grams of triethanolamine

[0030] 50 grams of glycerin, 150 grams of stearic acid, 20 grams of lanolin

[0031] 220 grams of white petrolatum, 1.5 grams of ethyl hydroxybenzoate, distilled water to 1000 grams

[0032] Preparation method: Melt stearic acid on a water bath, add lanolin and white petrolatum, and heat to 80°C in a water bath; dissolve triethanolamine, glycerin, and ethylparaben in water, and heat to 80°C on a water bath. Gradually add the oil phase to the water phase under continuous stirring, stir and condense to obtain an ointment, and finally add the finely ground drug crystals and stir evenly to obtain the product.

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PUM

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Abstract

The present invention relates to acne, which is also known as comedo, a chronic inflammatory disease of hair follicle and sebaceous glands. The acne usually occurs on the face, back and other positions of young people, and is represented as comedones, papule, pustule, tubercle, cyst, and so on. The acne is essentially a chronic inflammatory disease of hair follicle and sebaceous glands. After the inflammatory papule is treated, concave scars and temporary pigmentation can easily occur to seriously influence the physiognomy. In particular, when the acne conglobata is not cured in a long period, the patients suffer from spiritual pains. And the present invention relates to a medicinal composition which is used for treating or preventing acne. The medicinal composition comprises Japanese honeysuckle, Angelica dahurica, radix scutellariae, honeysuckle, rhubarb, aloe and so on, and has significant effects on the treatment and prevention of the acne.

Description

technical field [0001] The present invention relates to a pharmaceutical composition for preventing and treating acne. Specifically, it is an external preparation made of botanical medicines such as Yinhua. Background technique [0002] Acne, also known as acne, is a chronic inflammatory disease of the pilosebaceous glands. Occurs in young people, mainly on the face, chest and back. Manifested as blackheads, papules, pustules, nodules, cysts, etc. Its essence is the chronic inflammation of hair follicles and sebaceous glands. After the inflammatory papules subside, it is easy to leave depressed scars and temporary pigmentation. [0003] At present, the medical circle still lacks powerful measures for the prevention of acne, and there is no special effect means for the treatment of acne. Various families adopt comprehensive measures such as anti-inflammatory, desinsection, inhibition of sebaceous gland secretion, and improvement of immune function. Various medicines and p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K8/97A61Q19/06A61P17/10
Inventor 王士学
Owner 王士学
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