Compound magnesium sulfate wet-dressing agent and preparation method thereof

A magnesium sulfate wet compress and magnesium sulfate technology, applied in the medical field, can solve the problems of slow onset of pain relief and failure to meet clinical pain relief needs, and achieve shortened administration time, long drug effect time, and complete drug absorption Effect

Inactive Publication Date: 2009-02-18
贾国平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned method has a slow onset time for pain relief, and patients often need continuous wet compresses for several days to eliminate subcutaneous edema, which cannot meet the clinical pain relief needs of patients with chemotherapy, phlebitis, erysipelas, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Under 100,000-level clean production conditions, ① Take 450g of magnesium sulfate and add an appropriate amount of injection to dissolve as required; ② Take another appropriate container to dissolve 10g of lidocaine hydrochloride and add an appropriate amount of water for injection as required, and add water for injection to 1000ml; ③ Mix items ① and ② evenly, and filter with a sand stick with a pore size of 0.80 μm. The content of magnesium sulfate and lidocaine hydrochloride in the medicinal solution should meet the requirements after inspection; the pH value is controlled at 5.5; the medicinal solution is ready for use after passing the inspection. Put the sterilized gauze cut into sheets into the container, add the qualified medicinal solution for inspection and soak for 50 minutes, put it into a sterilized high-pressure and high-temperature resistant plastic bag and seal it (bag and seal It should be completed under the condition of local 10,000-level cleanliness),...

Embodiment 2

[0060] Under 100,000-level clean production conditions, ① Take 330g of magnesium sulfate and add an appropriate amount of injection to dissolve as required; ② Take another appropriate container to dissolve 20g of lidocaine hydrochloride and add an appropriate amount of water for injection as required, and add water for injection to 1000ml; ③ Mix items ① and ② evenly, and filter with a sand stick with a pore size of 0.80 μm. The content of magnesium sulfate and lidocaine hydrochloride in the medicinal solution should meet the requirements after inspection; the pH value is controlled at 6.5; the medicinal solution is ready for use after passing the inspection. Put the sterilized gauze cut into sheets into the container, add the qualified medicinal solution to soak for 30 minutes, put it into a sterilized high-pressure and high-temperature resistant plastic bag and seal it (bag and seal It should be completed under the condition of local 10,000-level cleanliness), and then put it...

Embodiment 3

[0062] Under 100,000-level clean production conditions, ① Take 500g of magnesium sulfate and add an appropriate amount of injection to dissolve as required; ② Take another appropriate container to dissolve 10g of lidocaine carbonate and add an appropriate amount of water for injection as required, and add water for injection to 1000ml; ③ Mix items ① and ② evenly, and filter with a sand stick with a pore size of 0.80 μm. The content of magnesium sulfate and lidocaine carbonate in the medicinal solution should meet the requirements after inspection; the pH value is controlled at 5.5; the medicinal solution is ready for use after passing the inspection. Put the sterilized gauze cut into sheets into the container, add the qualified medicinal solution to soak for 60 minutes, put it into a sterilized plastic bag resistant to high pressure and high temperature and seal it (bag and seal It should be completed under the condition of local 10,000-level cleanliness), and then put it into...

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PUM

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Abstract

The invention discloses a compound magnesium sulphate wet packing and a preparation method thereof. The compound magnesium sulphate wet packing consists of 20 to 50 percent of magnesium sulphate, 0.1 to 4 percent of lidocaine, the balance being surplus water for injection and medical carrier. The preparation method comprises the steps of soaking the medical carrier in compound magnesium sulphate solution for thirty to sixty minutes after being made into sheets and being disinfected and sterilized, sterilizing the medical carrier with steam for thirty to forty-five minutes, and then putting the medical carrier into a plastic bag to be sealed and packed to prepare the compound magnesium sulphate wet packing. The compound magnesium sulphate wet packing can effectively prevent chemotherapy phlebitis; and the clinical trials show that through the compound magnesium sulphate wet packing, the effective rate of caring and treating swelling and pain caused by edema on local subcutaneous tissue when chemotherapy drugs are instilled in the vein of the patient is over 90 percent, thereby reducing the pain of the patient effectively and improving the quality of life of the patient.

Description

technical field [0001] The invention belongs to the field of medical technology, and relates to a wet compress for preventing and treating swelling and pain caused by edema in local subcutaneous tissue, more specifically a compound magnesium sulfate wet compress with anti-inflammatory, swelling-relieving and pain-relieving effects and a preparation method thereof. Background technique [0002] In the commonly used clinical intravenous infusion, due to negligent management, non-corrosive drugs or corrosive drugs or solutions can easily enter the surrounding tissues and cause exudation and extravasation. Especially chemotherapy drugs have poor curative effect due to the small number of oral drugs. a major route of entry. However, many chemotherapeutic drugs are chemical and alkaloid preparations, coupled with repeated mechanical stimulation such as repeated punctures and strong local stimulation of high-concentration drugs, which can lead to redness, swelling, painful arterios...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/18A61L15/44
Inventor 贾国平
Owner 贾国平
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