76results about How to "Reduced dosing time" patented technology

A method and system for supply chain product and process development collaboration. The supply chain is comprised of at least one project, each project having a part (or family of parts), a supplier of the part, and a customer. The system may include a data storage and retrieval device operably connected to a processor. The system's functions include collaboration tools and security based on the users' project roles. The method uses a methodology that ensures certain requirements are met prior to satisfying the methodology. The system and method of the present invention ensures that current, applicable methodologies are applied to a specific part and allows for collaboration between the customer and supplier during all phases of the project. Because all projects in a supply chain are present, a user can navigate throughout the supply chain. The supply chain's reporting functions permit determination of potential performance risks and the source thereof.

The invention relates to surfactant for displacing the oil of an offshore oilfield and a preparation method thereof, and the surfactant and the preparation method thereof belong to the technical field of surfactants. The surfactant for displacing the oil of the offshore oilfield comprises the following components: hydroxypropyl sulfo betaine type amphoteric surfactant is adopted as the main agent and alkylphenol polyoxyethylene ether non-ionic surfactant serves as the auxiliary agent. The preparation method comprises the following steps that 1) the main agent is prepared: (1) water is adopted as the solvent to react with sodium hydrogen sulfite, sodium sulfite and epoxy chloropropane, and 3-chloro-2-hydroxypropyl sodium sulfonate is prepared; (2) low-carbon alcohol is adopted as the solvent, the product in the step (1) and emulsifier are dissolved, 12 / 14 tertiary amine is dripped in, and reflux reaction is carried out; (3) the tertiary amine and the solvent which do not react are removed, recrystallized and filtered; 2) assistant agent is selected; and 3) the main agent and the auxiliary agent are prepared by the mass ratio of 30 to 50: 30 to 90. The surfactant for displacing the oil of the offshore oilfield and the preparation method thereof have the advantages of ultra-low interfacial tension and good performance of emulsified crude oil, no toxin, no harm to the stratum, good compatibility, cooperation with polymer, microorganism and other flooding agent to displace oil and the like.

It is an object of the present invention to provide an enzyme preparation which is excellent in stability in blood (blood residence) and in transfer to a target organ (targeting property), and can be used effectively in enzyme replacement therapy or the like.This problem is solved by a lipid vesicle composition wherein vesicles composed of a lipid bilayer membrane are encapsulating an enzyme, the composition being capable of retaining stably the activity of the enzyme even outside the stable pH range of the enzyme.

There is provided an injection with torasemide as the main active ingredient in the invention, the preparing method of the injection is also included in the invention. The stability of the injection in the invention has been greatly improved. There is solubilizing agent and stabilizer in the preparation, the pH value is 9.0 or larger. The preparing method includes the following steps: adding 1-50% (by weight) of solubilizing agent to certain amount of injecting water; adding torasemide to the water, after it is completely dissolved, adding 0.1-5% part of stabilizer; adding water to requested amount and stirring uniformly; adding activated char to adsorb for 30min at high temperature; decarbonizing and filtering; adding medically used alkali to regulate the ph value to 9.0 or larger; aseptically filtering; after the assay is approved, packaging, degerming and stocking. The advantages of the invention include: high stability, short preparing time, low cost, no haemolyticus, blood vessel stimulus and allerfic response, low growing speed of relative substances.

Discloses is a method of manufacturing a micro-needle. The method includes a step of preparing a medicinal solution, a step of forming a plurality of tips with the medicinal solution, and a step of forming a cavity in each of the tips. In accordance with such a configuration, a micro-needle in which cavities are formed is provided, whereby it is possible to administer a fixed amount of medicine in a short time.

The invention discloses a continuous liquid preparing device for a medical supply room. The continuous liquid preparing device comprises a liquid preparing device body, a liquid mixing bin and liquidholding bins, wherein XTL100 electric telescopic rods are symmetrically arranged on two sides of the bottom of the liquid preparing device body; a second electromagnetic valve and a flow meter are sequentially arranged in the bottom center position of each liquid holding bin from top to bottom; a stirring rod is arranged inside the liquid mixing bin; a first electromagnetic valve is arranged at the bottom of the liquid mixing bin. In the continuous liquid preparing device disclosed by the invention, the second electromagnetic valve and the flow meter are sequentially arranged at the bottom ofeach liquid holding bin from top to bottom, and the bottom of each flow meter is communicated with the liquid mixing bin through a hose; the stirring rod with an S-shaped structure is arranged insidethe liquid mixing bin; liquid with different mixture ratios can be sufficiently mixed by a stirring action of the stirring rod and further liquid preparing time is shortened; besides, a prepared disinfectant can be quantitatively drained according to a calibration line etched on the outer part of the liquid mixing bin and the needs, so that waste of the disinfectant is effectively avoided, and thecost is reduced.

The invention discloses a water dispersible profile control agent for oil extraction and a preparation method thereof. The water dispersible profile control agent comprises the following components in parts by weight: 70-150 parts of acrylamide, 5-10 parts of anionic monomer, 5-10 parts of cationic monomer, 1-5 parts of hydrophobic monomer, 15-55 parts of dispersant, 30-85 parts of inorganic salt and 230-500 parts of deionized water. By virtue of water in water dispersion polymerization, the product is instant, so that the liquid preparation time and the curing time of a conventional polyacrylamide solution are shortened. A cationic chain link is introduced based on a conventional gel, so that gel molecules and rocks with negative electricity firmly adsorb so as to increase the flow resistance of water and improve the scouring resistance of the gel. The water dispersible profile control agent is low in initial viscosity, good in pumping property, simple in construction process and small in environmental damage. The water dispersible profile control agent is good in biological stability, and the profile control period of validity is over half a year. The product is obtained by virtue of water in water dispersion polymerization and is instant in the using process.

The invention relates to a preparation method of high viscosity cationic starch, which comprises the technological steps of: 1) using the mixture of an alkaline catalyst and an inhibitor to adjust the pH of starch slurry to be 10swung dash12; 2) heating and adding the mixture of an alkaline activating agent and a cationic etherifying agent, and stopping heating until the temperature reaches 40 DEG C; 3) using the mixture of the alkaline catalyst and the inhibitor to adjust the pH of the starch slurry to be 11swung dash12, keeping heating until the temperature of the starch slurry reaches 49swung dash50 DEG C, and etherifying for 1swung dash5h; 4) adding an alkaline cross-linking agent, and reacting for 1swung dash6h; and 5) dehydrating the starch slurry, obtaining green starch, adding an acidulant, mixing uniformly, acidizing the starch for 0.5swung dash2h at 50swung dash100 DEG C, and after cooling, smashing and screening, obtaining a product. The product has high paste viscosity, high acid and alkaline-resistant stabilities, and can be applied in the fields of paper making, mineral separation, oil fields, adhesives, waste water treatment and the like.

A spraying device for producing a spray of particles in a carrier gas at ambient pressure, includes a storage volume for a liquid substance; at least one nozzle having an inlet and an outlet, the nozzle inlet fluidly communicating with the storage volume; a counter electrode; an electric supply coupled between the at least one nozzle and counter electrode for providing a first potential and create a first electric field between the nozzle outlet and the counter electrode. The device further includes at least one discharge electrode coupled to the electric supply for providing a second potential between the discharge electrode and the counter electrode, the polarity of the second potential being opposite to the polarity of the first potential. The at least one nozzle and the at least one discharge electrode are arranged adjacent and parallel to each other and facing the counter electrode from a substantially same direction.

The invention relates to a novel fiber catheter and a preparation method thereof. The fiber catheter is internally provided with a cavity for transmitting liquid or gas and a fiber core layer for transmitting light. The top end of the fiber catheter is provided with a hemispherical or conical, cover which is a transparent cover. The cover is provided with a plurality of through holes which can release drug and light energy. The fiber catheter can be used for memorizing diameter change characteristics of metal and wave ducts, and fibers are pressed to be embedded into a polymer layer. According to the fiber catheter, drugs can be transported through the cavity, the fiber core layer with a high refractive index transmits light, the overall body of the novel fiber catheter can be bent and rotated, the drugs can be directly transported to lesions through a tiny pipeline such as a blood vessel, and the treatment of a photodynamic tumor is facilitated.

The invention provides a parecoxib sodium pharmaceutical composition for injection and a preparation method thereof. The parecoxib sodium pharmaceutical composition for injection has the advantages that prescription of the parecoxib sodium pharmaceutical composition for injection is simple, dosage of disodium hydrogen phosphate is decreased greatly as compared with that of the prior art, and requirement for injection medicine safety is met well; since parecoxib sodium is in the shape of crystal, time for dissolution is shortened and time for dosing is then shortened, quality stability is guaranteed, and production efficiency is improved; by a rapid freezing process during preparation, free-dried products maintain good pore structure with quite uniform granularity which is favorable for complete sublimation of moisture; since a nitrogen charge operation is omitted, production procedure is simplified, cost is reduced, and socialized mass production is facilitated.

The invention relates to a preparation method of a multifunctional slick water fracturing fluid drag reducer. The preparation method comprises the following steps: applying inverse emulsion polymerization reaction for compounding two non-ionic emulsifiers into a compound emulsifier, dissolving the compound emulsifier in an oily medium in the mass fraction of 0.3%, stirring for 1-2 hours under the protection of nitrogen, then adding 0.3% by mass fraction of a hydrophobic monomer, then adding 0.3-0.5% by mass fraction of a chelating agent and monomer solution of acrylamide and 2-acrylamide-2-methylpropanesulfonic acid, starting to heat, and after temperature is increased to 52-57 DEG C, adding an oil soluble initiator and a water soluble initiator in batches, and carrying out heat preservation for 8-10 hours after the initiator is completely added, so that stable water-in-oil type polymer emulsion is obtained finally. According to the invention, an inverse emulsion polymerization method is utilized, and by introducing special functional group substances and emulsifiers, a slick water drag reducer with anti-drag and discharge assisting functions is developed, slick water cost is reduced, more importantly, fluid preparation time is shortened, a fluid preparation procedure is simplified, and construction efficiency is greatly improved.

The invention discloses a compound magnesium sulphate wet packing and a preparation method thereof. The compound magnesium sulphate wet packing consists of 20 to 50 percent of magnesium sulphate, 0.1 to 4 percent of lidocaine, the balance being surplus water for injection and medical carrier. The preparation method comprises the steps of soaking the medical carrier in compound magnesium sulphate solution for thirty to sixty minutes after being made into sheets and being disinfected and sterilized, sterilizing the medical carrier with steam for thirty to forty-five minutes, and then putting the medical carrier into a plastic bag to be sealed and packed to prepare the compound magnesium sulphate wet packing. The compound magnesium sulphate wet packing can effectively prevent chemotherapy phlebitis; and the clinical trials show that through the compound magnesium sulphate wet packing, the effective rate of caring and treating swelling and pain caused by edema on local subcutaneous tissue when chemotherapy drugs are instilled in the vein of the patient is over 90 percent, thereby reducing the pain of the patient effectively and improving the quality of life of the patient.

The invention discloses a transfusion for restoring pulse beat, wherein each 1ml of the transfusion contains red ginseng 2-60mg, ophiopogon root 6.24-187.2mg, schisandra fruit 3.12-93.6mg, glucose and / or sodium chloride. The invention also discloses the process for preparing the transfusion.

The invention relates to sterilized magnesium sulfate wet dressing agent. It is formed by medical using magnesium sulfate aqueous solution and carrier. The former accounts for 20-50wt%, and can be made by high temperature sterilizing after sand stick filtering with 0.50-0.80mum aperture. The latter can be the water absorption paper towel, gauze, or medical using dressing. It can be used to cure local subcutaneous tissue swelling ache. The using method includes the following steps: dressing it along the vein direction, changing for every 30-60min until to the dripping off, stopping the wet dressing after withdrawing the needle for 1-2h. The user can understand clearly through the direction for use on the packaging bag which can solve the problems of carryover, using inconvenient, and infection.

The invention discloses an accurate PEG (polyethylene glycol) liquid pumping device which comprises a vehicle body, a liquid storage tank, a liquid conveying pump and a liquid outgoing pipeline. Traveling wheels are mounted at the bottom of the vehicle body, a controller is mounted on one side of the vehicle body, the liquid storage tank is arranged on the vehicle body, the liquid conveying pump is mounted at the bottom of one end of the liquid storage tank, a liquid outgoing end of the liquid conveying pump is connected with the liquid outgoing pipeline, a flowmeter is arranged on the liquid outgoing pipeline, and the controller is in communication connection with both the flowmeter and the liquid conveying pump. By accurate feedback of the flowmeter and automatic control of the controller, manual intervention in the process of operation can be reduced, multiple pumping vehicles can be operated by one person simultaneously, and working efficiency and metering accuracy are high. The automatic controller can effectively avoid artificial operation errors. In addition, the accurate PEG liquid pumping device is compact in overall structure and convenient in moving on a working site.

The invention provides a pharmaceutical composition for treating viral infection of respiratory system. The pharmaceutical composition contains chloroquine and a sputum-removing drug. The sputum-removing drug is selected from at least one of acetylcysteine, ambroxol or ammonium chloride. The invention provides a preparation method of the pharmaceutical composition for preventing and treating diseases caused by virus infection of a human respiratory system. The medicine composition of the chloroquine and sputum-removing drug is prepared into a spray, an aerosol or an inhalation preparation forpreventing and treating the diseases caused by the virus infection of the human respiratory system.

The invention discloses an MBR plate-type membrane cleaning agent, which comprises an alkaline cleaning agent and / or an acidic cleaning agent, and can efficiently remove various pollutants remained onthe surface and in the membrane pores of an ultrafiltration membrane. The invention also provides an MBR plate-type membrane cleaning method, wherein the cleaning agent is beaten into a plate-type membrane in a cross-flow circulation manner, standing aerating scrubbing is performed, and the residual cleaning agent in the membrane is recovered, so that the defects that the chemical cleaning of theexisting plate-type membrane is non-uniform and the agent cannot be recovered can be overcome, and the chemical cleaning strength and the membrane performance recovery rate after chemical cleaning are effectively improved so as to prolong the chemical cleaning period and the service life of the MBR plate-type membrane system.

The invention relates a single-step discontinuous method for producing pasteable polymers, in particular, vinyl chloride homopolymers and copolymers according to the microsuspension method. When they are mixed with softeners, said polymers turn into PVC-pastes, also know as plastisols, having very low viscosities and a reduced emulsifier content.

The present invention relates to a low molecular heparin iron nanoparticle biological product. The invention further relates to a preparation method for the low molecular heparin iron nanoparticles. According to the present invention, the preparation method for the low molecular heparin iron nanoparticles with excellent slow release function is provided; with the method, the low molecular heparin iron nanoparticles capable of slow release of LMWH in vivo can be obtained, and the heparin administration time and the times of the heparin administration can be effectively reduced with the drug.

Certain example embodiments relate to articles supporting photocatalytic layers that also include UV-reflecting underlayers, and / or methods of making the same. In certain example embodiments, the inclusion of a UV-reflecting underlayer surprisingly and unexpectedly results in the reduction of dosing time to enable quick activation of the photocatalytic coating. For example, dosing time may be reduced from a few hours to a few minutes or even seconds in certain example embodiments. The UV-reflecting underlayer may be a single-layer coating or a multi-layer stack.

The invention relates to a rhEndostatin injection. The rhEndostatin injection is mainly composed of a stabilizer, a buffer solution and rhEndostatin. The rhEndostatin injection provided by the invention has the advantages of high concentration and good stability, and can replace the traditional intravenous drip injection solution, the drug administration time is obviously shortened, the physical pain of a patient is reduced, and the clinical compliance of the patient is improved.

The invention relates to a preparation method of a multifunctional slick water fracturing fluid drag reducer. The preparation method comprises the following steps: applying inverse emulsion polymerization reaction for compounding two non-ionic emulsifiers into a compound emulsifier, dissolving the compound emulsifier in an oily medium in the mass fraction of 0.3%, stirring for 1-2 hours under the protection of nitrogen, then adding 0.3% by mass fraction of a hydrophobic monomer, then adding 0.3-0.5% by mass fraction of a chelating agent and monomer solution of acrylamide and 2-acrylamide-2-methylpropanesulfonic acid, starting to heat, and after temperature is increased to 52-57 DEG C, adding an oil soluble initiator and a water soluble initiator in batches, and carrying out heat preservation for 8-10 hours after the initiator is completely added, so that stable water-in-oil type polymer emulsion is obtained finally. According to the invention, an inverse emulsion polymerization method is utilized, and by introducing special functional group substances and emulsifiers, a slick water drag reducer with anti-drag and discharge assisting functions is developed, slick water cost is reduced, more importantly, fluid preparation time is shortened, a fluid preparation procedure is simplified, and construction efficiency is greatly improved.

The invention relates to surfactant for displacing the oil of an offshore oilfield and a preparation method thereof, and the surfactant and the preparation method thereof belong to the technical field of surfactants. The surfactant for displacing the oil of the offshore oilfield comprises the following components: hydroxypropyl sulfo betaine type amphoteric surfactant is adopted as the main agent and alkylphenol polyoxyethylene ether non-ionic surfactant serves as the auxiliary agent. The preparation method comprises the following steps that 1) the main agent is prepared: (1) water is adopted as the solvent to react with sodium hydrogen sulfite, sodium sulfite and epoxy chloropropane, and 3-chloro-2-hydroxypropyl sodium sulfonate is prepared; (2) low-carbon alcohol is adopted as the solvent, the product in the step (1) and emulsifier are dissolved, 12 / 14 tertiary amine is dripped in, and reflux reaction is carried out; (3) the tertiary amine and the solvent which do not react are removed, recrystallized and filtered; 2) assistant agent is selected; and 3) the main agent and the auxiliary agent are prepared by the mass ratio of 30 to 50: 30 to 90. The surfactant for displacing the oil of the offshore oilfield and the preparation method thereof have the advantages of ultra-low interfacial tension and good performance of emulsified crude oil, no toxin, no harm to the stratum, good compatibility, cooperation with polymer, microorganism and other flooding agent to displace oil and the like.

The invention relates to a slime water mixed dosing and filter press linkage system and method for coal dressing. According to the invention, a first automatic dosing belt is used for adding an anionic agent into a first funnel, and a second automatic dosing belt is used for adding a cationic agent into a second funnel; the first funnel, a gas ring vacuum pump, a mixing device, a stirring barrel,a chemical storage box, a dosing device, a concentration tank, a filter pressing feeding barrel and a filter press are sequentially connected through connecting pipelines; the second funnel is connected with the stirring barrel; a slime water main pipe is connected with the concentration tank; a feeding concentration meter and a first flow meter are installed on the slime water main pipe; an interface instrument, an underflow concentration meter and a second flow meter are installed in the concentration tank; and an electromagnetic valve, a current measuring meter and a filtrate water flow meter are installed on the filter press. According to the invention, automatic combined dosing is achieved, manpower is reduced, and labor intensity is reduced; agent waste can be effectively reduced, and a dosing process can be more accurately controlled; equipment investment can be reduced, and cost is effectively reduced; and dosing time is shortened and working efficiency is improved.

The invention discloses a rectal administration device with an electric adjusting function for the gastroenterology department. The rectal administration device comprises a fixing pipe, a round head and a silica gel protective cover, wherein a blocking cover is arranged on the fixing pipe in a penetrating mode; a soft sliding column is slidably connected into the fixing pipe through a limiting mechanism, and the right end of the fixing pipe is connected with an electric telescopic rod through a connecting plate; and the telescopic end of the electric telescopic rod is connected with the rightend of a soft sliding column through a mounting plate. The rectal administration device with the electric adjusting function for the gastroenterology department is simple in structure, low in manufacturing cost and easy to operate, the rectal administration time can be shortened, the silica gel protective cover cannot hurt the rectum of a patient, and the pain of the patient is relieved. The softsliding column can be driven to move in the fixing pipe through the mounting plate by stretching and retracting of the electric telescopic rod, so that the round head with the medicine moves to the medicine feeding depth, the medicine feeding depth can be controlled, and the treatment effect is improved.

The invention belongs to the technical field of medicine, especially the field of chemical pharmacy, and relates to a plerixafor-containing composition for injection and a preparation method and application thereof. The plerixafor-containing composition for injection has a pH value of 6 to 8 and is in the form of a stable aseptic aqueous solution of water-soluble plerixafor. According to the invention, solubility of plerixafor in an aqueous solution during dosing is substantially improved, dosing time is reduced, stability of a finished product is improved, and potential safety hazards to patients caused by clarity of the product in clinical medication are avoided.

The invention relates to a method and a device for the compression injection moulding of preforms (10) by means of an injection moulding machine comprising one movable and one fixed tool carrier plate (2, 5) and a mould with a plurality of mould nests or cavities (60), the movable mould half (8) being designed with cores (24) and the melt being introduced into the cavities (60) on the fixed mould-half (9) side via controlled valves. The cores (24) penetrate the mould nests or cavities (60) before completion of the melt dosage to such a depth that said mould nests are at least substantially closed to the exterior. The melt is introduced into the mould nests or cavities (60) when the moulds are not completely sealed, the valves are closed and the compression pressure is produced by means of the cores (24) by the complete closure of the moulds.

The invention provides a pharmaceutical composition of parecoxib sodium for injection and a preparation method thereof. The pharmaceutical composition of parecoxib sodium for injection provided by the invention has the advantages of simple prescription, and the dosage of disodium hydrogen phosphate is greatly reduced compared with the prior art, which is more in line with the requirements of injection drug safety; Quickly, shorten the liquid preparation time, ensure stable quality, and improve production efficiency; the method of rapid freezing and cooling is adopted in the preparation process, so that the freeze-dried product maintains a good pore structure and forms a very uniform particle size, which is conducive to moisture It is fully sublimated; the nitrogen filling operation is omitted, the production process is simplified, the cost is reduced, and it is more conducive to socialized large-scale production.

The invention belongs to the field of pharmaceutical preparations and particularly relates to a sulfotanshinone IIA sodium lyophilized powder injection preparation and a preparation method thereof. The lyophilized powder injection preparation comprises the following components: 1 part by weight of sulfotanshinone IIA sodium, 4-30 parts by weight of a skeleton support agent and 0.015-0.1 parts by weight of a pH regulator, wherein the pH regulator contains one or more of sulfuric acid or sulfate. The pH regulator is added, so that the pH of the preparation can be stabilized in a proper range, and the stability of the preparation is improved greatly.