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Compositions comprising silicone pressure sensitive adhesives for delivering oral care substances

A technology of silicone pressure-sensitive adhesive and oral care, which is applied in the direction of drug combination, oral care, anti-virus, etc., and can solve the problems of complex application and self-treatment.

Inactive Publication Date: 2011-11-16
PROCTER & GAMBLE CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While this barrier coating can provide benefits in terms of increased durability, it requires the use of special equipment and complex application
Therefore, it cannot be done at home and used for self-treatment

Method used

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  • Compositions comprising silicone pressure sensitive adhesives for delivering oral care substances
  • Compositions comprising silicone pressure sensitive adhesives for delivering oral care substances
  • Compositions comprising silicone pressure sensitive adhesives for delivering oral care substances

Examples

Experimental program
Comparison scheme
Effect test

example

[0106] The following examples further describe and demonstrate embodiments within the scope of the present invention. The examples given are illustrative only and are not to be construed as limitations of the invention, since many changes can be made without departing from the spirit and scope of the invention.

example I

[0107] Example 1 - Tooth Whitening Composition

[0108] The present compositions may advantageously be used in tooth bleaching or whitening applications. An example of a tooth whitening composition according to the invention is a fluid composition which can be applied to the teeth by brushing, by applying to the surface of tooth enamel or by adhering a strip coated with the composition to the teeth apply. The substantially anhydrous hydrophobic silicone pressure sensitive adhesives of the present invention provide a stable vehicle that prevents the decomposition of whitening agents such as peroxides during storage and prior to use. When applied to the teeth, the applied whitening composition forms an adherent layer of the whitening agent-containing product that releases the whitening agent over an extended period of time, such as from about 5 minutes to overnight The product. The applied layer adheres to the tooth surface whereby the whitening agent released then whitens ...

example II

[0121] Example II. Bleaching Performance

[0122] The bleaching performance of the compositions on inherent tooth stains can be assessed using the following procedure. The extracted human molars are removed from any soft tissue and polished / cleaned to remove any calculus or foreign stain. The molar sample is mounted to a Lego Baselines and CIE L*a*b* values ​​were measured using a Fuji HC1000 digital camera under controlled light conditions (D55 light) with polarizing filters. The molars were then rehydrated overnight in water or phosphate buffered saline. Thereafter, the molars were removed from the solution to be treated with the test composition. Separate each test strip from the release liner and wrap around each molar. A few drops of human saliva were added to each test molar. The molars were then placed in a 37°C incubator during processing. Each molar was treated with the composition for 30 minutes twice daily throughout the study period (4 or more days). Afte...

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Abstract

Disclosed are compositions for delivering one or more oral care substances to the oral cavity, comprising: (a) a silicone pressure sensitive adhesive selected from a silicone / resin copolymer with silicon-bonded hydroxyl radicals, a silicone / resin copolymer with endcapped silicon-bonded hydroxyl radicals and mixtures thereof; (b) a plasticizing material; (c) a water-soluble bioadhesive polymer; (d) a hydrophilic surfactant, and (e) at least one oral care substance. The silicone / resin copolymer is prepared by polycondensing a silanol endblocked polydialkylsiloxane and a hydroxyl endblocked silicate resin. The polycondensation product may be further reacted with a trialkylsilyl endcapping agent to reduce the number of hydroxyl radicals in the polymer. Further disclosed are methods of using these compositions, such as for teeth bleaching and whitening applications.

Description

field of invention [0001] The present invention relates to compositions for delivering oral care substances to oral surfaces, such as teeth. The composition forms an adhesive film on the surface to which it is applied and provides sustained release of the oral care substance from the film for prolonged therapeutic, prophylactic, and / or cosmetic benefit. Background of the invention [0002] Oral care products by which various oral care substances or actives can be delivered to the soft and hard tissues of the oral cavity have been previously disclosed. Examples of such oral care products include, for example, brushing aids, such as dentifrice products for delivering anti-caries actives such as fluoride or other actives for reducing plaque-causing bacteria, and breath-containing Mouthwashes with freshening actives and / or antibacterial actives. In addition, bleaching agents, such as peroxides, have been developed that can be applied directly to the tooth surface (ie, tooth en...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/21A61K8/22A61K8/81A61K8/86A61K8/89A61Q11/00A61Q11/02
CPCA61K8/892A61Q11/00A61K8/898A61P1/02A61P25/04A61P29/00A61P29/02A61P31/02A61P31/04A61P31/10A61P31/12A61P39/06A61P43/00A61K8/89A61Q11/02A61K8/22A61K8/86
Inventor 尚沙勒·库马尔·高希萨蒂亚纳拉扬·马耶蒂斯蒂芬·安德拉什·科瓦克斯
Owner PROCTER & GAMBLE CO