Pharmaceutical composition containing gliclazide

A Glichetide and composition technology, applied in the field of sustained-release pharmaceutical compositions, can solve problems such as poor water solubility and incomplete release of the main drug, and achieve the effect of increasing water solubility
CN101468028AInactive Publication Date: 2009-07-01北京德众万全医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
北京德众万全医药科技有限公司
Publication Date
2009-07-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to pharmaceutical composition with gliclazide and preparation method thereof. By producing solid dispersion, the invention improves the releasing rate of the medicament, so as to achieve better sustained-release purpose. The pharmaceutical composition applied to the treatment of diabetes, and reduces the frequency of injecting medicine and helps stabilize the blood concentration of the patients, meanwhile, the adaptability is increased too.
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Description

technical field

[0001] The invention relates to a sustained-release pharmaceutical composition for treating diabetes, in particular to a sustained-release pharmaceutical composition containing gliclazide solid dispersion. Background technique

[0002] Gliclazide is a second-generation sulfonylurea hypoglycemic drug (also known as methylsulfonylurea), which is a commonly used hypoglycemic drug in clinical practice. Due to its definite curative effect, it is included in the National Essential Drug List and medical insurance drug. Currently, ordinary oral tablets containing 80 mg of gliclazide are used clinically. However, the short-term plasma concentration of its active ingredients reaches a peak in the patient's body, resulting in toxic and side effects. Sustained-release preparations can effectively solve this problem, making the blood drug concentration of active ingredients in the patient's body balanced and stable, and avoiding the occurrence of drug poisoning peaks. ...

Claims

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