Compound anesthetic for dogs

Abstract

The invention relates to a compound anesthetic for dogs, which belongs to the technical field of veterinary drug preparation and is suitable for stopping and anesthetizing dogs. The preparation method of the compound anesthetic for dogs comprises the following steps: sequentially dissolving 0.3g of citric acid, 1g of sodium citrate, 0.09g of methyl p-hydroxybenzoate, 0.01g of propyl p-hydroxybenzoate, 8g of ketamine hydrochloride, 0.2g of midazolam hydrochloride and 0.9g of xylazine hydrochloride into water for injection for preparing each 100ml of solution, filtering the solution, filling and sealing the solution into an ampoule, and sterilizing to obtain the compound anesthetic. The compound anesthetic for dogs preferably selects the formula through an orthogonal test, integrates the advantages of each drug, greatly reduces the side effect when each drug is used singly, and has stable anesthetizing and waking processes. Compared with the prior art, the induction time, the maintaining time, the stage of surgical anesthesia and the waking time are respectively shortened by 81.67%, 81.45%, 73.33% and 48.28%, and the anesthetizing controllability is greatly improved; the influence on each physiological parameter is little; and moreover, the compound anesthetic is taken intravenously, thus the dose can be supplemented for many times according to the operation requirements, and the compound anesthetic can be used for complicated operations and long-lasting operations.

Description

1. Technical field [0001] The invention relates to a compound anesthetic for dogs, belonging to the technical field of veterinary drug preparation. It is suitable for immobilization and anesthesia of dogs. 2. Background technology [0002] The purpose of veterinary clinical anesthesia is to ensure animal safety, meet surgical needs, relieve pain and treat injuries. With the advancement of domestic veterinary clinical anesthesia technology, traditional single anesthesia can no longer meet the needs of clinical anesthesia. Single anesthesia has been replaced by compound anesthesia, and the related research and application of compound anesthesia preparations has become a new trend in the development of modern veterinary anesthesia. [0003] At present, domestic drugs for clinical anesthesia of canine diseases mainly include compound anesthesia preparations such as Sumianxin and Quanmianbao. Sumianxin and Quanmianbao have good sedative, analgesic and muscle relaxing effects, ...

AI Technical Summary

Problems solved by technology

[0008] Technical Problem The purpose of the present invention is to rationally combine the three drugs of ketamine, midazolam and xylazine to achieve better anesthesia effect and the lowest side effects, while overcoming the induction time, maintenance time and recovery time in the prior art. It takes a long time and has a great impact on the respiratory and circulatory system; and it is administered by intramuscular injection, it is difficult to control the depth and maintenance time of anesthesia, and it is difficult to apply to anesthesia for complex or long-term operations.

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