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Zhenhuang tablet for treating sore throat and ulcer and sore furuncle and preparation method thereof

A technology for sore throat and Zhenhuang tablets, which is applied in the field of Zhenhuang tablets and its preparation, can solve the problems of backward technology, affecting the formation of plain tablets, and high waste rate, and achieve the effects of shortening the production cycle and preventing the leakage of volatile oil

Active Publication Date: 2012-01-11
LANXI PHARMA FACTORY OF ZHEJIANG PROV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because the technical solution itself is immature, there are some deficiencies, which are mainly reflected as follows: 1. The production efficiency of manual granulation with ethanol is low, and it is not suitable for mass production; The hardness of plain tablets is low, and the waste rate is high; 3. The technology of coating with corn protein and hydroxypropyl methylcellulose is backward; 4. Pig bile is not easy to preserve and is inconvenient to use

Method used

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  • Zhenhuang tablet for treating sore throat and ulcer and sore furuncle and preparation method thereof
  • Zhenhuang tablet for treating sore throat and ulcer and sore furuncle and preparation method thereof
  • Zhenhuang tablet for treating sore throat and ulcer and sore furuncle and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0118] Take 11.2 parts of pearls, 45 parts of artificial bezoar, 90 parts of Panax notoginseng, 56.3 parts of Scutellaria baicalensis extract, 2.8 parts of borneol, 8 parts of pig gall powder, and 5.6 parts of peppermint oil.

[0119] 2.8 parts of borneol are dissolved in 5.6 parts of peppermint oil, and set aside; 90 parts of Panax notoginseng are crushed into fine powder, 11.2 parts of pearl are ground or water-flyed into very fine powder; Mix with the above powder; use 3% simple syrup as the binder, set the material temperature to 46°C, set the inner layer pressure of the spray gun to 1.0-1.5bar, the outer layer pressure to 2.0-3.0bar, and control the flow rate to 14-25Hz Carry out granulation; add an appropriate amount of magnesium stearate and talcum powder, press into tablets, spray into peppermint oil dissolved in borneol, mix well, and seal it for 24 hours; set the air inlet and outlet temperatures to 98°C and 45°C, set the package The rotating speed of the clothing po...

Embodiment 2

[0121] Take 10 parts of pearls, 44 parts of artificial bezoar, 89 parts of Panax notoginseng, 55 parts of Scutellaria baicalensis extract, 2 parts of borneol, 3 parts of pig gall powder, and 5 parts of peppermint oil.

[0122] Dissolve 2 parts of borneol in 5 parts of peppermint oil and set aside; crush 89 parts of Panax notoginseng into fine powder, grind 1 part of pearl or fly it into fine powder with water; mix 44 parts of artificial bezoar, 55 parts of scutellaria baicalensis extract, and 3 Mix with the above powder; use 3% simple syrup as the binder, set the material temperature to 46°C, set the inner layer pressure of the spray gun to 1.0-1.5bar, the outer layer pressure to 2.0-3.0bar, and control the flow rate to 14-25Hz Carry out granulation; turn off the heating system after the granules meet the requirements, and continue boiling until the granules are cooled to room temperature; dissolve borneol and purified water as a spray liquid, and set the pressure of the inner ...

Embodiment 3

[0124] Take 12 parts of pearls, 46 parts of artificial bezoar, 91 parts of Panax notoginseng, 57 parts of Scutellaria baicalensis extract, 3 parts of borneol, 15 parts of pig gall powder, and 6 parts of peppermint oil.

[0125] Dissolve 3 parts of borneol in 6 parts of peppermint oil and set aside; 91 parts of Panax notoginseng are crushed into fine powder, 12 parts of pearl are ground or water-flyed into very fine powder; Mix with the above powder; use 3% simple syrup as the binder, set the material temperature to 46°C, set the inner layer pressure of the spray gun to 1.0-1.5bar, the outer layer pressure to 2.0-3.0bar, and control the flow rate to 14-25Hz Carry out granulation; add an appropriate amount of magnesium stearate and talcum powder, press into tablets, spray into peppermint oil dissolved in borneol, mix well, and seal it for 24 hours; set the air inlet and outlet temperatures to 98°C and 45°C, set the package The rotating speed of the clothing pot is 3-4 rpm, the f...

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Abstract

The invention provides a preparation method of Zhenhuang tablet for treating sore throat and ulcer and sore furuncle, and the Zhenhuang tablet is prepared from pearl, artificial bezoar, pseudo-ginseng, extractum radix scutellariae, borneol, pulvis fellis suis and peppermint oil. Compared with the prior art, the preparation of the invention improves the shortages of the original formula and technology, prolongs the quality guarantee period of medicine, improves curative effect and is more suitable for industrial volume production. The preparation of the invention has the efficacy of clearing away heat and toxic material, reducing swelling and easing pain, is used for treating sore throat and ulcer and sore furuncle clinically, has obvious curative effect, convenient use and stable and controllable quality and is worth popularizing and applying clinically.

Description

Technical field: [0001] The invention relates to a kind of Zhenhuang tablets with the functions of clearing away heat and detoxification, reducing swelling and relieving pain, which is used for sore throat, sores and boils, and a preparation method thereof, belonging to the technical field of traditional Chinese medicine pharmacy. Background technique: [0002] Zhenhuang tablet is composed of pearl, bezoar, notoginseng, scutellaria baicalensis extract, borneol, peppermint oil, and pig gall powder. [0003] The Niuhuang in the prescription of Zhenhuang Tablets can clear away heat and detoxify, clear away heart-fire and resolve phlegm. Modern pharmacology has proved that it contains ingredients such as cholic acid and deoxycholic acid, which can reduce the excitement of the central nervous system, thereby producing sedative and analgesic effects. Sore throat, sore tongue, carbuncle and furunculosis caused by external heat disturbance have obvious therapeutic effects; Panax not...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/28A61K35/413A61K35/618A61K36/539A61P11/04A61P17/02
Inventor 王天亮樊雪君王永华
Owner LANXI PHARMA FACTORY OF ZHEJIANG PROV