Novel method for detecting piperacillin sodium and sulbactam sodium for compound injection
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- XIANGBEI WELMAN PHARMA CO LTD
- Publication Date
- 2010-10-06
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
Background of the invention:
[0001] Piperacillin sodium is a semi-synthetic penicillin antibiotic with broad-spectrum antibacterial activity. Piperacillin is effective against Enterobacteriaceae such as Escherichia coli, Proteus, Serratia, Klebsiella, Enterobacter, Citrobacter, Salmonella and Shigella, as well as Pseudomonas aeruginosa Other Gram-negative bacteria, such as Monas, Acinetobacter, Haemophilus influenzae, and Neisseria, all have good antibacterial effects. This product also has a certain antibacterial activity against Enterococcus, Group A, Group B hemolytic streptococcus, Streptococcus pneumoniae and staphylococci that do not produce penicillinase. Many anaerobic bacteria, including Bacteroides fragilis and Clostridium, are also sensitive to piperacillin. The mechanism of action of piperacillin is to exert a bactericidal effect by inhibiting the synthesis of bacterial cell walls.
[0002] Due to the large and extensive clinical application, and even the emerge...