Medicine for preventing and treating pediatric saprodontia and preparation method thereof

A caries and medicine technology, applied in the field of medicines and preparations for the prevention and treatment of children's caries, can solve the problems of edema, induction and aggravation of infection, etc., and achieve the effect of strong patient adaptability, simple medicine prescription and clear curative effect

Inactive Publication Date: 2010-10-20
李贺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, long-term application of antibacterial drugs may cause some side effects, such as edema, high blood pressure, induction and aggravation of infection, etc.
Moreover, topical application of antibiotics is prone to drug resistance, and long-term topical application can also cause flora imbalance and fungal infection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Weigh 50 grams of Scutellaria baicalensis, 80 grams of Magnolia officinalis, 30 grams of Forsythia, 10 grams of capillary, 30 grams of gall, 50 grams of honeysuckle, 10 grams of Acanthopanax, 100 grams of green tea, 50 grams of safflower, 150 grams of honey and 500 grams of water. gram, placed in a sealed flask, heated in a water bath at 70°C for 2 hours, filtered, and the filtrate was collected to obtain mouthwash.

[0014] When using mouthwash, generally use 10-20ml at a time. When using the mouthwash of the present invention, it can be rinsed several times after a meal, or it can be taken in the mouth for several minutes at a time. Mouthwash can be spit out or swallowed directly.

experiment example 1

[0015] Experimental example 1: Study on antibacterial activity against oral cariogenic bacteria in vitro

[0016] Streptococcus mutans and actinomycetes viscous are considered to be the most important cariogenic bacteria. They form dental plaque by adhering to the tooth surface and cause dental caries. Therefore, inhibiting and killing cariogenic bacteria is of great importance in the prevention and treatment of caries. important role. In this experimental example, the classic filter paper method in the art is used to carry out the antibacterial test, wherein:

[0017] 1. Materials

[0018] 1.1 Bacteria to be tested

[0019] Actinomycetes viscosus (A.viscosus ATCC 15987) and Streptococcus mutans (S.mutans ATCC 25175) were purchased from Shanghai Sanda Biotechnology Co., Ltd.

[0020] 1.2 Culture medium

[0021] Nutrient agar and nutrient broth were purchased from Shanghai Sanda Biotechnology Co., Ltd.

[0022] 1.3 Test method

[0023] Inoculate Actinomycetes viscosus (A....

experiment example 2

[0027] 1. Clinical data

[0028] 40 cases of children with mild to moderate caries were selected as observation objects, all of which met the diagnostic and grading criteria of "Caries Science" (Edited by Yue Songling. 1st edition, Chengdu: Sichuan People's Publishing House, 1983: 224-225, 280-281). Randomly divided into test group and control group. Among them, there were 20 cases in the test group, with an age range of 4-7 years, with an average age of 5.6 years, including 10 cases of men and women; 20 cases of the control group, with an age range of 4-7 years, with an average age of 5.4 years, including 10 cases of men and women.

[0029] 2. Observation method

[0030] The test group uses the mouthwash prepared in Example 1, 3 times a day, gargles after meals, 20ml each time, and gargles for 30 seconds, and 3 months is a course of treatment. The control group did not use the mouthwash of the present invention. The daily eating and living habits of the experimental group ...

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Abstract

The invention relates to medicine for preventing and treating pediatric saprodontia, which belongs to a medical agent prepared from the following raw medicine by weight parts: 4 to 8 parts of radix scutellariae, 6 to 10 parts of magnolia officinalis, 1 to 5 parts of forsythia, 1 to 3 parts of capillary artemisia, 1 to 5 parts of nutgall, 3 to 6 parts of honeysuckle, 1 to 5 parts of acanthopanax, 10 to 15 parts of green tea, 3 to 7 parts of safflower and 10 to 20 parts of honey. The invention also provides a preparation method of the medicine for preventing and treating pediatric saprodontia. The recipe of the medicine for preventing and treating pediatric saprodontia of the invention is simple, the price is low, the curative effect is obvious, the patient adaptability is strong, and the invention is suitable for being widely popularized in clinics.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medicine for preventing and treating dental caries in children and a preparation method thereof. Background technique [0002] Fluoride prevention of caries has gone through more than 40 years, including various measures such as adding fluoride to drinking water, fluoride-containing milk or fluoride-containing salt, and local application of fluoride (fluoride-containing toothpaste, fluoride-containing gel, fluoride-containing mouthwash). It is recognized as an effective caries prevention measure in the world to reduce the caries prevalence rate in the population to the greatest extent. People in the field of stomatology once pointed out that "fluoride prevention of caries is one of the major achievements in oral preventive medicine in the 20th century", but the measurement of the benefits and harms of fluoride on the human body is still a controversial topic in the field of stomatology....

Claims

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Application Information

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IPC IPC(8): A61K36/82A61K9/20A61K9/00A61P1/02A61P31/04A61K35/64A61K35/644
Inventor 赵丽侠
Owner 李贺
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