Scanning objective of laser co-focusing micro-endoscope

Abstract

The invention relates to a scanning objective of a laser co-focusing micro-endoscope, comprising four lens systems. The scanning objective can couple laser beams with different incident angles in a body, thereby carrying out scanning and lighting on in-vivo tissues at different positions and stimulating fluorescence labeling at a scanning position, so that a fluorescence signal is coupled to an in-vivo detector. The scanning objective of the laser co-focusing micro-endoscope of the invention can realize imaging with high resolution and high definition and has the advantages of large numerical aperture, high sensitivity and microminiaturization.

Description

technical field [0001] The invention relates to a laser confocal microendoscope, in particular to a laser confocal microendoscope scanning objective lens. Background technique [0002] Medical endoscopes have become necessary equipment for detection and diagnosis of lesions in the body and minimally invasive surgery, and are widely used in various fields of clinical medicine. The current endoscopic diagnosis is to observe the tissues in the body on a macro scale, identify suspicious areas, and if necessary, take suspicious tissues out of the body for histopathological diagnosis. This is an invasive process, accompanied by risks such as bleeding, infection, and early missed diagnosis. Confocal laser confocal endoscopy can realize real-time high-resolution histopathological diagnosis of internal organs without sampling biopsy, and can use fluorescent contrast agent, which has strong specificity and is an important method for non-invasive diagnosis of early lesions, especially ...

AI Technical Summary

Problems solved by technology

The fiber optic bundle allows the confocal scanning mechanism to be placed outside the body, and the endoscopic probe can be small, but the image clarity is seriously affected by the grid arrangement of the fiber bundle itself, the resolution of the confocal image is low, and due to the adjacent core Light crosstalk makes it difficult to improve the contrast of the image; a single fiber requires the confocal scanning mechanism to be placed in the body, which is difficult to implement and has a large size, and neither the fiber bundle nor a single fiber can correct the aberration of the endoscope system

[0004] Some endoscopes use the Hopkins image relay system. Compared with the general image relay system, the brightness at the edge of the field of view is greatly improved, but the numerical aperture of the Hopkins image relay system is small, resulting in low resolution. In addition, the Hopkins image relay system is Combining a dozen to dozens of lenses, the energy loss is large, and it is difficult to assemble

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