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Application of traditional Chinese medical composition in preparation of medicament for resisting influenza A H1N1 influenza viruses

A composition and technology of traditional Chinese medicine, applied in antiviral agents, active ingredients of hydroxyl compounds, pharmaceutical formulas, etc.

Active Publication Date: 2011-03-30
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Neuraminidase exists on both type A and type B influenza viruses, so oseltamivir is effective for both type A and type B influenza virus infections. The drug greatly reduces the virus that is spread through sneezing, but it cannot completely to stop

Method used

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  • Application of traditional Chinese medical composition in preparation of medicament for resisting influenza A H1N1 influenza viruses
  • Application of traditional Chinese medical composition in preparation of medicament for resisting influenza A H1N1 influenza viruses

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] The raw material drug formula is:

[0091] Forsythia 255g Honeysuckle 255g Banlangen 255g Rhubarb 51g Patchouli 85g Mianma Guanzhong 255g Rhodiola 85g Menthol 7.5g Honey ephedra 85g Fried bitter almond 85g Houttuynia cordata 255g Licorice 85g Gypsum 255g

[0092] The preparation method is:

[0093] (1) Take the Chinese medicinal materials according to the above-mentioned prescription, select them cleanly, and break them into pieces as appropriate;

[0094] (2) Patchouli is broken, add 6 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0095] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extract 2 times with 8 times the amount of 70% ethanol, the first time for 2 hours, the second time for 1.5 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for...

Embodiment 2

[0100] The raw material drug formula is:

[0101] Forsythia 300g Honeysuckle 200g Banlangen 300g Rhubarb 60g Patchouli 100g Mianma Guanzhong 200g Rhodiola rosea 60g Menthol 5g Ephedra 100g Bitter almond 60g Houttuynia cordata 300g Licorice 60g Gypsum 300g

[0102] The preparation method is:

[0103] (1) Take the Chinese medicinal materials according to the above-mentioned prescription, select them cleanly, and break them into pieces as appropriate;

[0104] (2) Patchouli is broken, add 5 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0105] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extract 2 times with 6 times the amount of 50% ethanol, the first time for 3 hours, the second time for 1 hour, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for subseque...

Embodiment 3

[0110] The raw material drug formula is:

[0111] Forsythia 200g Honeysuckle 300g Radix Radix 200g Rhubarb 60g Patchouli 60g Mianma Guanzhong 300g Rhodiola 60g Menthol 9g Ephedra 60g Bitter almond 100g Houttuynia cordata 200g Licorice 100g Gypsum 200g.

[0112] The preparation method is:

[0113] (1) Take the Chinese medicinal materials according to the above-mentioned prescription, select them cleanly, and break them into pieces as appropriate;

[0114] (2) Patchouli is broken, add 10 times the amount of water to extract the volatile oil, the oil extraction time is 4 hours, collect the volatile oil, and set aside; after the extract is filtered, the residue is discarded, and the filtrate is set aside;

[0115] (3) forsythia, ephedra, houttuynia cordata, rhubarb, extract 2 times with 10 times the amount of 90% ethanol, the first time for 1 hour, the second time for 3 hours, the extracts are combined and filtered, the ethanol is recovered, and the filtrate is used for subsequen...

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Abstract

The invention discloses the application of a traditional Chinese medical composition in the preparation of a medicament for resisting influenza A H1N1 influenza viruses. The traditional Chinese medical composition is prepared from the medical materials of forsythia, honeysuckle, ephedra, bitter almond, and the like, has broad-spectrum antiviral action, can effectively kill the viruses, reduce fever and diminish inflammation. Proved by experiments, the traditional Chinese medical composition can accurately resist the influenza A H1n1 influenza viruses.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines against influenza A (H1N1) virus, which belongs to the field of traditional Chinese medicine applications. Background technique [0002] Influenza A virus H1N1 subtype is a type of influenza A virus and one of the most commonly infected influenza viruses in humans. Some H1N1 species can spread between humans, including the 1918 influenza pandemic, and others can spread between birds and pigs. [0003] The genetic makeup of this virus is controversial. Based on the type of hemagglutinin protein and neuraminidase it had, scientists agreed it was an H1N1 virus. It is made up of genetic material from human, swine and bird flu, while the World Health Organization believes it is mostly made up of swine flu genes. [0004] The novel H1N1 influenza was origina...

Claims

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Application Information

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IPC IPC(8): A61K36/78A61K9/48A61K9/16A61P31/16A61K33/06A61K31/045
Inventor 贾振华魏聪
Owner BEIJING YILING PHARMA
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