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Celery seed extract composition and preparation method thereof

A technology of celery seed extract and composition, which is applied in the field of medicine, and can solve the problems that the stability of flavonoid components cannot meet the requirements, etc.

Active Publication Date: 2011-05-11
BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide a kind of liquid composition that can be used for the treatment of the celery seed ethanol extract of gout, and its preparation method, to overcome the stability of flavonoids component when celery seed ethanol extract is formulated into liquid composition Problems that do not meet the requirements

Method used

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  • Celery seed extract composition and preparation method thereof
  • Celery seed extract composition and preparation method thereof
  • Celery seed extract composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Embodiment 1, the preparation of composition

[0065] Formulations of example compositions:

[0066]

[0067] Capsule shell formula when made into soft capsules:

[0068]

[0069]

[0070] Prepare as follows:

[0071] (1) Preparation of capsule skin materials: Measure pure water and put it into a plastic tank, heat it in a water bath to 70-80°C, add gelatin, add glycerin, methylparaben and titanium dioxide after dissolving, stir evenly, and keep the temperature at 70°C -80°C, vacuumize and degas, keep warm at 55-60°C and stand for use.

[0072] (2) Preparation of the liquid composition: take the celery seed extract and mix it with the diluent that has added the suspending agent, then add additives such as antioxidant, stir evenly, and let stand at room temperature; get the liquid composition of the present invention , half of which are subpackaged in oral liquid bottles, and half are used in the following steps (3) to prepare soft capsules;

[0073](3) Mo...

Embodiment 2

[0074] Embodiment 2, the preparation of composition

[0075] Formulations of example compositions:

[0076]

[0077] Capsule shell formula when made into soft capsules:

[0078]

[0079] Prepare as follows:

[0080] (1) Preparation of capsule skin materials: Measure pure water and put it into a plastic tank, heat it in a water bath to 70-80°C, add gelatin, add glycerin, methylparaben and titanium dioxide after dissolving, stir evenly, and keep the temperature at 70°C -80°C, vacuumize and degas, keep warm at 55-60°C and stand for use.

[0081] (2) Preparation of the liquid composition: take the celery seed extract and mix it with the diluent that has added the suspending agent, then add additives such as antioxidant, stir evenly, and let stand at room temperature; get the liquid composition of the present invention , half of which are subpackaged in oral liquid bottles, and half are used in the following steps (3) to prepare soft capsules;

[0082] (3) Move the prep...

Embodiment 3

[0083] Embodiment 3, the preparation of composition

[0084] Formulations of example compositions:

[0085]

[0086] Capsule shell formula when made into soft capsules:

[0087]

[0088] Prepare as follows:

[0089] (1) Preparation of capsule skin materials: Measure pure water and put it into a plastic tank, heat it in a water bath to 70-80°C, add gelatin, add glycerin, methylparaben and titanium dioxide after dissolving, stir evenly, and keep the temperature at 70°C -80°C, vacuumize and degas, keep warm at 55-60°C and stand for use.

[0090] (2) Preparation of the liquid composition: take the celery seed extract and mix it with the diluent that has added the suspending agent, then add additives such as antioxidant, stir evenly, and let stand at room temperature; get the liquid composition of the present invention , half of which are subpackaged in oral liquid bottles, and half are used in the following steps (3) to prepare soft capsules;

[0091] (3) Move the prep...

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Abstract

The invention relates to a celery seed extract composition and a preparation method thereof. The composition contains 30-90 parts by weight of celery seed extract, 10-70 parts by weight of thinner, 0.01-1 part by weight of antioxidant, and optional suspending agent, surfactant and preservative. The invention further relates to a soft capsule preparation containing the composition or an oral liquid preparation containing the composition, and the preparation method of the composition or a preparation method of the preparation. The composition is reasonable in types of accessories and a main drug, reasonable in matching dose and convenient to administrate, and has the advantages of stability, safety, rapid response, high bioavailability, small side effects, small administration dose and the like. The preparation method has the characteristics of simple process and stable product quality, and is easy to control.

Description

Technical field: [0001] The invention belongs to the field of medicine, and relates to a composition of celery seed extract and a preparation method thereof, in particular to a composition made of ethanol extract of celery seed which can be used to treat gout, such as oral liquid or soft capsule and its preparation method. Background technique: [0002] Celery seed is the seed of Apium graveolens L., an umbelliferous plant celery. Celery, also known as parsley and dry celery, is recorded in "Luxianyan Materia Medica". It is an annual or biennial herb of Umbelliferae, and it is cultivated all over the country and around the world. Celery seed is often used in condiments and foods. Celery seed tea has a significant effect on promoting sleep. Its extract has a contraction effect on pregnant and non-pregnant uteri and can be used to treat dysmenorrhea. Traditional Chinese medicine believes that celery seed has the effects of dispersing qi, reducing swelling, diuresis, opening ...

Claims

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Application Information

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IPC IPC(8): A61K36/23A61K9/00A61K9/48A61P19/06A61K131/00
Inventor 李莉娥蔡正军伊进朝陈海生高永良
Owner BEIJING HUMANWELL JUNWEI PHARM TECH CO LTD
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