A component traditional Chinese medicine for treating cardiac insufficiency in coronary heart disease and its preparation method

A technology of cardiac insufficiency and traditional Chinese medicine, applied in the field of pharmaceutical composition for the treatment of cardiac insufficiency in coronary heart disease, effective components in the field of traditional Chinese medicine, can solve hyperkalemia, the survival rate has not been significantly improved, and clinical trials are still in progress, etc. problems, to achieve the effect of improving purity, reducing costs, and reducing adverse reactions

Active Publication Date: 2011-11-30
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The 2007 Guidelines for the Diagnosis and Treatment of Cardiac Insufficiency Conventional treatment of heart failure includes the combined use of angiotensin-converting enzyme inhibitors (ACEI)/angiotensin II receptor blockers (ARB) and β-blockers to treat cardiac function. Insufficiency, although it can effectively improve the symptoms and signs of patients with heart failure, it is generally difficult to preven...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0008] Aconite 9g Astragalus 30g Salvia 15g Silver flower 10g Scrophulariaceae 10g Licorice 6g

Embodiment 2

[0010] Aconite 9g Astragalus 10g Salvia miltiorrhiza 15g Silver flower 10g Scrophulariaceae 10g Licorice 10g

Embodiment 3

[0012] Aconite 6g Astragalus 20g Salvia 10g Silver flower 15g Scrophulariaceae 15g Licorice 10g

[0013] Weighing the medicines, respectively carrying out the proportioning after extraction of the effective components of each traditional Chinese medicine in the prescription, such as the active components of Astragalus membranaceus (manufactured), the total saponins of Astragalus membranaceus, including astragalosides Ⅰ, Ⅴ, Ⅲ, etc.; Active components of alkaloid compounds, including aconitine, mesoaconitine, hypoaconitine, etc.; effective components of licorice saponins, including glycyrrhizic acid, glycyrrhetinic acid, glycyrrhizin and glycyrrhizin polysaccharides, etc.; Salvia miltiorrhiza The effective components of phenolic acid compounds, including salvianolic acid, proto-chicaldehyde, proto-chicic acid, etc.; the effective components of Scrophulariaceae, containing paioside, etc.; the effective components of honeysuckle organic Acid compounds, including chlorogenic acid, ...

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PUM

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Abstract

The invention relates to a Chinese medicine composition for treating coronary disease and cardiac insufficiency and a preparation method thereof. The invention provides a Chinese medicine composition for treating chronic heart failure and a preparation method thereof. The composition comprises 10-30 weight portions of radix astragali, 10-20 weight portions of salvia miltiorrhiza, 5-15 weight portions of monkshood, 10-15 weight portions of radix scrophulariae, 10-20 weight portions of honeysuckle flower and 5-15 weight portions of licorice, and prepared by extracting the effective ingredients of the formula with a certain preparation technology, then mixing the ingredients according to the dosages and preparing into the granular formulation. A patient needs to take one packet of the Chinese medicine composition two times per day.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicinal compositions, in particular to a medicinal composition for treating cardiac insufficiency due to coronary heart disease, which is an effective component traditional Chinese medicine with functions of nourishing Qi and Yang, promoting blood circulation and detoxification. Background technique [0002] Cardiac insufficiency (heart failure), which is a change in myocardial structure and function due to initial myocardial injury from any cause (eg, myocardial infarction, cardiomyopathy, hemodynamic overload, inflammation, etc.) that eventually leads to ventricular pumping and / or Low filling function. Clinical pathogenesis and clinical manifestations include symptoms such as dyspnea, weakness, and fluid retention caused by myocardial remodeling. Epidemiological surveys show that the 6-year mortality rate of heart failure patients is as high as 80% for men and 65% for women; the annual mort...

Claims

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Application Information

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IPC IPC(8): A61K36/808A61K9/16A61P9/04
Inventor 王伟郭淑贞张鹏倪健
Owner BEIJING UNIV OF CHINESE MEDICINE
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