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A sugar-free Fenghanmao granule and preparation method thereof

A technology for wind-cold colds and granules, which is applied in the direction of medical formulas, medical preparations containing active ingredients, etc., which can solve the problems of increasing the burden on pancreatic islets and aggravating diseases, and achieve good solubility and sweetness. The effect of moderate taste and high content of amygdalin

Active Publication Date: 2011-12-14
GUANGDONG YIFANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to overcome the defect that the traditional Fenghanmao granule is added with a large amount of sucrose which affects its use, and to provide a sugar-free Fenghanmao granule

Method used

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  • A sugar-free Fenghanmao granule and preparation method thereof
  • A sugar-free Fenghanmao granule and preparation method thereof
  • A sugar-free Fenghanmao granule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0077] Ephedra 10kg, Pueraria 15kg, Perilla leaf 15kg, Fangfeng 15kg, Guizhi 10kg, Angelica dahurica 10kg, Tangerine peel 10kg, Bitter almond 15kg, Platycodon grandiflorum 10kg, Licorice 10kg, Dried ginger 10kg, Steviol glycoside 500g, Carboxymethyl starch sodium 1000g, Malto paste Fine amount.

[0078] Take the above eleven decoction pieces, extract volatile oil from perilla leaves, windproof, and angelica dahurica, add dregs and other medicinal materials to decoct in water, the steps of adding water to decoct are: first add 9 times the total amount of water, boil, first add bitter For almond decoction pieces, heat the extraction tank while feeding to keep it in a slightly boiling state. Put the bitter almonds into the extraction tank according to the principle of a small amount and several times. The temperature in the tank is controlled at 95°C-100°C. Pueraria lobata, cinnamon twig, tangerine peel, platycodon, licorice, dried ginger and seven herbs, decocted for 3 hours, fi...

Embodiment 2

[0090] Ephedra 10kg, Pueraria 15kg, Perilla leaves 15kg, Fangfeng 15kg, Guizhi 10kg, Angelica dahurica 10kg, Tangerine peel 10kg, Bitter almond 15kg, Platycodon grandiflorum 10kg, Licorice 10kg, Dried ginger 10kg, Steviol glycoside 400g, Carboxymethyl starch sodium 2000g, Malto paste Fine amount.

[0091] Take the above eleven decoction pieces, extract volatile oil from perilla leaves, windproof, and angelica dahurica, add dregs and other medicinal materials to decoct, the steps of adding water to decoct are: first add ephedra, kudzu root, cinnamon sticks, tangerine peel, platycodon grandiflorum, licorice 1. Dried ginger and seven herbs, add water 7 times the weight of the total feed, boil, then add the bitter almond slices, heat the extraction tank while feeding, keep a slight boiling state, put the bitter almond slices into the extraction tank according to the principle of a small amount and multiple times , the temperature in the tank is controlled at 95°C to 100°C. After t...

Embodiment 3

[0093] Ephedra 10kg, Pueraria 15kg, Perilla leaves 15kg, Fangfeng 15kg, Guizhi 10kg, Angelica dahurica 10kg, Tangerine peel 10kg, Bitter almond 15kg, Platycodon grandiflorum 10kg, Licorice 10kg, Dried ginger 10kg, Steviol glycoside 600g, Carboxymethyl starch sodium 1500g, Malto paste Fine amount.

[0094] Take the above eleven decoction pieces, extract volatile oil from perilla leaves, windproof and Angelica dahurica, add water to decoct herbal dregs and other medicinal materials, the steps of adding water to decoct are as follows: add the total weight of 10 double the amount of water, boil, put the bitter almond decoction pieces first, heat the extraction tank while feeding, keep a slight boiling state, put the bitter almond decoction pieces into the extraction tank according to the principle of a small amount and multiple times, and control the temperature in the tank at 95 ° C ~ 100 ° C After the feeding is completed, boil again, add ephedra, kudzu root, cinnamon twig, tang...

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Abstract

The invention relates to sugar-free granules for treating wind-cold type common cold and preparation method thereof. The granules are mainly composed of main materials and auxiliary materials, wherein the main materials comprise ephedra, kudzu root, purple common perilla leaf, radix sileris, cassia twig, radix angelicae, dried orange peel, bitter almond, Platycodon grandiflorus, licorice root anddried ginger; and the auxiliary materials main comprise stevioside, sodium starch glycolate and a right amount of maltodextrin. The preparation method comprises the following steps: extracting volatile oil from purple common perilla leaf, radix sileris and radix angelicae for later use, and feeding the dregs, which are obtained after extracting the volatile oil, and the other main materials in a required sequence; decocting three times, filtering, and concentrating the filtrate under reduced pressure until the relative density reaches 1.05-1.15 (60 DEG C), thereby obtain clear paste; carryingout spray drying to obtain extractum powder; adding the screened auxiliary materials into the extractum powder, and adding into a dry-process granulator to obtain 10-30 mesh granules; and spraying the extracted volatile oil, evenly mixing and packaging. The granules prepared by the method provided by the invention are free of sucrose, and consume fewer auxiliary materials; compared with the original granules, the granules prepared by the method provided by the invention have the advantages of greatly reduced dose and lower production cost; and after the technique is improved, the content of the effective constituent amygdalin is high.

Description

technical field [0001] The invention relates to a Ganmao granule and a preparation method thereof, in particular to a sugar-free Fenghan Ganmao granule and a preparation method thereof, belonging to the technical field of traditional Chinese medicine granules. Background technique [0002] The prescription of Fenghanmao granules comes from page 45 of the first volume of Chinese Drug Standards. Indications: relieve sweating, dispel wind and cold. For anemofrigid cold, fever, headache, aversion to cold, no sweat, cough, nasal congestion, runny nose. [0003] There are more than 50 companies producing Fenghanmao granules in the country. The main manufacturers are Guangdong Yifang Pharmaceutical, Yunnan Baiyao, Sanjiu Pharmaceutical, Ningxia Qiyuan Pharmaceutical, Wuhan Jianmin Pharmaceutical, etc. The annual sales of such products of each enterprise are in the It ranges from a few million yuan to tens of millions of yuan. A small number of production enterprises are large a...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/16A61K47/36G01N30/02A61P11/00
Inventor 谭登平魏梅张德雄张光大汪梅陈向东
Owner GUANGDONG YIFANG PHARMA