Method for preparing nanostructured lipid carrier (nlc) and product

A nanostructured lipid and carrier technology, applied in liposome delivery, nanotechnology, nanotechnology, etc., can solve the problems of high heating stability and heating process reduction
CN102283809AInactive Publication Date: 2011-12-21马来西亚棕油理事会

Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
马来西亚棕油理事会
Publication Date
2011-12-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

PURPOSE: A method for preparing a nanostrucutured lipid carrier or nanoemulsion is provided to reduce inflammation and to ensure chemical stability. CONSTITUTION: A method for preparing a nanostrucutured lipid carrier or nanoemulsion comprises: a step of dissolving an oil phase at higher temperature than the temperature of an oil phase containing solid lipid, liquid lipid, or mixture thereof and lipophilic and hydrophilic surfactant; a step of adding active ingredients to the dissolved oil phase; a step of homogenizing the oil phase; a step of mixing the oil phase with a first aqueous solution and preheating; a step of forming pre-emulsion; and a step of homogenizing the pre-emulsion.
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Description

technical field

[0001] The present invention relates to a method of producing NLC, wherein the NLC not only serves as a delivery system, but is capable of retaining a large amount of active ingredients in it - especially antioxidants, without degrading most of the active ingredients in the process. Background technique

[0002] Nanostructured lipid carrier (NLC), which is composed of solid lipid as matrix and added a certain amount of liquid lipid, is regarded as the new generation of solid nanoparticles. NLC has been recognized in the field of cosmetics for its ability to improve the chemical stability of active ingredients, increase skin hydration through occlusive effects, increase the bioavailability of active ingredients on the skin, and increase the physical stability of topical formulations. received great attention. Due to the above characteristics, NLC is considered as an ideal delivery system for active ingredients (such as carotene, tocol, coenzyme Q, etc.) used ...

Claims

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