Blood lipid-lowering composite food

A technology for lowering blood lipid and food, which is applied in the composition of Grifola frondosa polysaccharide and sesamin to assist in the field of blood lipid lowering health food, and achieves the effects of improving clinical symptoms, enhancing pharmacological activity, and applying safety.

Inactive Publication Date: 2012-02-22
HEFEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no report on the use of Grifola frondosa

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0024] Example 1:

[0025] A combination food for reducing blood fat is composed of Grifola frondosa polysaccharide powder and sesamin powder in a mass ratio of 1:1 evenly mixed.

[0026] The preparation process of Grifola frondosa polysaccharide powder is as follows: Grifola frondosa fruiting bodies are ground into powder, and about 3 times the volume of 95% ethanol solution is added for stirring and degreasing, maintaining for 2 hours, and suction filtering to obtain a precipitate. Accurately weigh a certain amount of precipitate, add distilled water with a material-to-liquid ratio of 1:10 (g / ml), and extract at high pressure at 120°C for 30 minutes. Centrifuge, take the supernatant, add 1:1 volume of absolute ethanol for precipitation for 12 hours. Centrifuge, take the precipitate, vacuum dry at 60°C, and weigh to obtain Grifola frondosa polysaccharide powder, and determine the content (mg / g) of Grifola frondosa polysaccharide. The properties of this product are: light brown p...

Example Embodiment

[0033] Example 2:

[0034] A combination food for reducing blood fat is composed of Grifola frondosa polysaccharide powder and sesamin powder in a mass ratio of 1:2 evenly mixed.

[0035] Grifola frondosa polysaccharide powder was purchased from Zhejiang Qingyuan County Hongyi Agricultural Development Co., Ltd.

[0036] Sesamin powder was purchased from Nanjing Zelang Agricultural Technology Co., Ltd.

[0037] Tablet preparation, according to the tablet preparation process to prepare tablets. Each tablet contains Grifola frondosa polysaccharide + sesamin 20mg+40mg.

[0038] Others are the same as in Example 1.

Example Embodiment

[0039] Example 3:

[0040] A combination food for lowering blood lipids is a mixture of Grifola frondosa polysaccharide powder extracted from Grifola frondosa fruiting bodies and sesamin powder extracted from sesame meal in a ratio of 2:1.

[0041] Grifola frondosa polysaccharide powder was purchased from Zhejiang Qingyuan County Hongyi Agricultural Development Co., Ltd.

[0042] Sesamin powder was purchased from Nanjing Zelang Agricultural Technology Co., Ltd.

[0043] For the preparation of the capsule, the capsule is prepared according to the capsule preparation process. Each capsule contains Grifola frondosa polysaccharide + sesamin 40mg+20mg.

[0044] Others are the same as in Example 1.

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Abstract

The invention relates to blood lipid-lowering composite food, which is composed by mixing grifola frondosa polysaccharide (GFP) powder and sesamin (SES) powder uniformly in a mass ratio of 1:2-2:1. The GFP powder is extracted form grifola frondosa fruit bodies, wherein, the GFP content is greater than 50%. And the SES powder is extracted from sesame meal, wherein, the SES content is over 50%. Pharmacological experiments show that, the food of the invention can lower the blood lipid level of a hyperlipidemia mice model, and can protect hepatocyte injury caused by hyperlipidemia; also can realize synergetic enhancement of pharmacological activity, and better improve the blood lipid-lowering function of each component. Toxicological experiments show that, the composition of the invention is safe for application. The composition provided in the invention can be used for preparing health food and medicaments assisting lowering blood lipid, and can lower the blood lipid level as well as improve clinic symptoms resulted from hyperlipidemia.

Description

technical field [0001] The invention belongs to the technical fields of health food and biomedicine, and in particular relates to a health food for assisting in reducing blood fat, that is, a combination of grifola frondosa polysaccharide and sesamin from natural sources. Background technique [0002] With the improvement of people's living standards, the incidence of hyperlipidemia is increasing year by year. The curative effect of most lipid-lowering chemicals is unstable, and long-term use has certain toxic and side effects. Use modern research methods to develop natural products, and develop health food whose active ingredients are derived from food and traditional Chinese medicine, which can assist the use of chemicals to reduce drug dosage and reduce toxic and side effects; it is suitable for mild patients and can be taken for a long time; It has important social value to reduce the blood lipid level of patients with hyperlipidemia, improve the symptoms of patients, a...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L33/00
Inventor 雷红张霄祥郭淑臻
Owner HEFEI UNIV OF TECH
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