Non-drug treatment system for inactivation of HIV (human immunodeficiency virus) and other viruses

A virus inactivation and treatment system technology, applied in the treatment of infectious diseases, safe blood transfusion, and blood products, can solve the problems that patients and society cannot afford, high treatment costs, drug side effects, etc., to achieve suitable promotion and reduce HIV load, no toxic side effects

Active Publication Date: 2012-03-28
ZHENGZHOU FEILONG MEDICAL EQUIP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, the severe side effects of drugs, the drug resistance of the virus and the immune evasion...

Method used

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  • Non-drug treatment system for inactivation of HIV (human immunodeficiency virus) and other viruses
  • Non-drug treatment system for inactivation of HIV (human immunodeficiency virus) and other viruses

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1: When the blood is collected from the human body by the blood sampler and flows into the pipeline, the anticoagulant is injected through the anticoagulant and the protective cap; at this time, the saline return needle and the protective cap pipeline are closed, and the blood injected with the anticoagulant passes through the blood filter Flow into the plasma separation cup, close the tube-shaped plasma collection ultra-high pressure virus inactivation treatment bag pre-pipeline and cake-shaped plasma collection inactivation photochemical treatment bag before a section of pipeline without MB self-dosing fort, the plasma flowing out of the plasma separation cup passes through The channel equipped with MB self-dosing fort enters the cake-shaped plasma collection and inactivation photochemical treatment bag, and the front end of the cake-shaped plasma collection and inactivation photochemical treatment bag is equipped with MB self-dosing fort, and MB is added ins...

Embodiment 2

[0012] Embodiment 2: When the blood is collected from the human body by the blood sampler and flows into the pipeline, the anticoagulant is injected through the anticoagulant and the protective cap; at this time, the saline return needle and the protective cap pipeline are closed, and the blood injected with the anticoagulant passes through the blood filter Flow into the plasma separation cup, close the pre-stop clamp of the cake-shaped plasma collection and inactivation photochemical treatment bag, and the plasma flowing out of the plasma separation cup enters the cylindrical plasma collection ultra-high pressure inactivation treatment bag, the capacity can be 200ml-800ml, and the plasma passes through the pipeline Flow into the cylindrical plasma collection ultra-high pressure inactivation treatment bag. When the quantitative plasma is reached, the plasma collection machine will automatically transfuse blood cells, and then cut off the pipeline for fusion, and put the cylindri...

Embodiment 3

[0013] Example 3: Inactivation by HHP plasma virus inactivation instrument and MB plasma virus inactivation instrument can also be used in combination to perform double virus inactivation.

[0014] The invention also has the inactivation effect on non-enveloped viruses except lipid-enveloped viruses such as HIV. Such as EMCV, 300MPa, 3Min after inactivation can reduce more than 7.0log, TCID. Therefore, it also has an effective therapeutic effect on opportunistic infections caused by gamma virus and other infections.

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Abstract

The invention relates to a treatment system for carrying out autologous plasma virus inactivation for non-drug antivirus treatment on patients infected by lipid-enveloped viruses including HIV (human immunodeficiency virus) and the like caused by drug-resistant strains and variant strains. The treatment system comprises a plasma collector, a disposable separation and virus inactivation multi-purpose processor for collected plasma, an MB virus inactivator and an HHP virus inactivator, wherein the disposable separation and virus inactivation multi-purpose processor for collected plasma comprises a blood collector, a pipeline, a plasma separation cup, a lengthened plasma pipeline, a photochemical processing bag for pancake plasma collection and inactivation, a processing bag for tubular plasma collection and extra-high-pressure virus inactivation, an MB self-medicating pot, a puncture cap, a retaining clip, a blood filter, a pressure monitor, a saline water reinfusion needle and protection cap thereof, and an anticoagulant and protection cap thereof. The invention has the advantages of wide application range, good virus inactivation effect, wide spectrum of inactivated viruses, convenient operation process, high safety and efficiency and low cost, thereby being suitable to be popularized.

Description

technical field [0001] The invention is a non-drug HIV and other virus inactivation treatment system, which belongs to the fields of infectious disease treatment, safe blood transfusion and blood products. Background technique [0002] AIDS (AIDS) Chinese full name: Acquired Immunodeficiency Syndrome. It is a highly contagious new viral infectious disease caused by HIV infection. Decades of catastrophic harm to human beings have been known all over the world. Since 1981, countries have invested huge amounts of financial, material, scientific and social resources in the development of drugs and vaccines. However, due to the fact that AIDS virus has quite a lot of unknown self-characteristics, the ideal drug and method that can completely cure the disease have not been found so far, and there is no effective preventive vaccine. As of 2010, my country has reported more than 370,000 HIV / AIDS cases, including 68,000 deaths. The Ministry of Health released an estimated total of...

Claims

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Application Information

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IPC IPC(8): A61M1/36
Inventor 张新民孙锦山
Owner ZHENGZHOU FEILONG MEDICAL EQUIP CO LTD
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