Sterilizing mixer

Abstract

The invention relates to a pharmaceutical machine, particularly to a sterilizing mixer. The sterilizing mixer comprises a rack, a power device and a material mixing device, wherein the power device is arranged on the rack, and the material mixing device is connected with a PTO (power take-off) main shaft of the power device and rotates along the main shaft; the material mixing device comprises a material mixing drum body and a material exit which is arranged at the bottom of the material mixing drum body, the material exit is provided with a connecting device which is connected with a material drum and can be sealed with the material drum, and the material mixing drum body above the connecting device is also provided with a feed / discharge butterfly valve; and an air breathing apparatus and a cleaning device are arranged on the material mixing drum body. Due to the structure, the sterilizing mixer provided by the invention has the advantages that: the risk of polluting materials is reduced, an effect of online cleaning, sterilizing and drying is achieved, the labor intensity of workers is reduced, the finished product ratio of medicaments and the pharmaceutical efficiency are improved, and the sterilizing mixer also conforms to 2010-version GMP (Good Manufacturing Practice) requirements.

Description

technical field [0001] The invention relates to aseptic mixing equipment in the process of producing medicines, specifically an aseptic mixing machine that can reduce the risk of drug contamination, meets the requirements of the national GMP version 2010, and can also clean, sterilize, and dry the aseptic mixing equipment on-line . Background technique [0002] At present, the feeding and discharging of aseptic mixing equipment in the process of domestic drug production mostly adopts manual or vacuum methods. During the operation of these two methods, people often come into contact with materials, which aggravates the material being trapped by particles or The risk of microbial contamination leads to a high rate of waste products produced; while the existing aseptic mixing equipment usually uses manual in-place cleaning or off-line cleaning during the cleaning, sterilization, and drying processes, the cleaning water and drainage during in-place cleaning Both require manual ...

AI Technical Summary

Problems solved by technology

However, the aseptic mixing equipment of the prior art cannot meet the national GMP requirements of the 2010 version at all. At the same time, the aseptic mixing equipment of the prior art spends a lot of time in contact with people during the production, cleaning, sterilization, and drying processes, and materials and aseptic mixing High risk of contamination of equipment with particulates or microbes, resulting in high reject rates for produced pharmaceutical products

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