Pseuoginsenoside-Rh 2 and application to preparation of tumor treating medicine

A technology for simulating ginsenosides and antitumor drugs, applied in the field of traditional Chinese medicine, can solve problems such as different side chain structures, and achieve the effect of obvious curative effect
CN102391345AInactive Publication Date: 2012-03-28JILIN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
JILIN UNIV
Publication Date
2012-03-28
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a new compound pseuoginsenoside-Rh2, a preparation method of the compound and an application of the compound to preparation of a tumor treating medicine. Both the compound and the ginsenoside-Rh2 are tetracyclic triterpenoid compounds; beta-D-glucopyranose is boned at the positions 3 of the compound and the ginsenoside-Rh2 respectively; the structures of the lateral chains are different; and both the compound and the ginsenoside-Rh2 have degradation products of panoxadiol saponin and have an anticancer effect.
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Description

technical field

[0001] The invention discloses a new compound pseudo-ginsenoside-Rh2, and provides a preparation method of the compound; meanwhile, it also discloses the use of the compound in preparing antitumor drugs, belonging to the technical field of traditional Chinese medicine. Background technique

[0002] Research on ginsenosides began in the early 1960s. Ginsenoside Ra has been isolated from the roots, stems, leaves, flowers, and fruits of Araliaceae plants such as ginseng, American ginseng, and Panax notoginseng. 1 、Ra 2 、Ra 3 , Rb 1 , Rb 2 , Rb 3 , Rc, Rd, Re, Rg 1 , Rg 2 , Rg 3 , Rf , F 1 , F 2 , Rh 1 、Rh 2 More than 50 kinds of tetracyclic triterpenoid ginsenosides. According to the different saponins of compounds, they are divided into several categories, among which Ra 1 、Ra 2 , Ra, Rb 1 , Rb 2 , Rb 3 , Rc, Rd, Rg 3 、Rh 2 Their saponins are 20(S)-protopanaxadiol, so they belong to protopanaxadiol type saponins; and Re, Rg 1 , Rg 2 , Rf, ...

Claims

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