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Ophthalmic composition for silicone hydrogel contact lens

A silicone hydrogel and contact lens technology is applied in the deformation of silicone hydrogel contact lenses and the friction field of silicone hydrogel contact lenses. deformation effect

Active Publication Date: 2014-04-30
ROHTO PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current situation is that the effect of the combined use of chlorhexidine or cyclodextrins with polyoxyethylene hydrogenated castor oil is completely unknown, and the effect of the combination of the two on silicone hydrogel contact lenses is even more completely unpredictable

Method used

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  • Ophthalmic composition for silicone hydrogel contact lens
  • Ophthalmic composition for silicone hydrogel contact lens
  • Ophthalmic composition for silicone hydrogel contact lens

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0148] Hereinafter, although this invention is demonstrated in detail based on an Example, this invention is not limited to these Examples.

[0149] Reference Test Example 1: Evaluation of Dimensional Changes in Soft Contact Lenses

[0150] The following tests were implemented using the three types of soft contact lenses shown in Table 1, and the amount of change in the size of the soft contact lenses was evaluated.

[0151] [Table 1]

[0152]

[0153] USAN: the name of the lens material BC: base arc DIA: lens diameter

[0154]Specifically, evaluation was performed by the following method. First, one piece of each soft contact lens in Table 1 was immersed in 5 mL of physiological saline, and left to stand for 24 hours to stabilize the lens size. After 24 hours, each lens was moved to a chamber filled with physiological saline, and the chamber was installed in a universal projector (product name: PROFILE PROJECTOR V-12B, manufactured by Nikon) to measure the size (initi...

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Abstract

Disclosed is an ophthalmic composition for a silicone hydrogel contact lens, which can prevent the deformation of a silicone hydrogel contact lens caused by the action of polyoxyethylene hydrogenated castor oil. Specifically disclosed is an ophthalmic composition for a silicone hydrogel contact lens, which contains (A) polyoxyethylene hydrogenated castor oil and additionally contains (B) at least one compound selected from the group consisting of chlorhexidine compounds and cyclodextrin compounds.

Description

technical field [0001] The present invention relates to an ophthalmic composition for silicone hydrogel contact lenses, which can inhibit the deformation of silicone hydrogel contact lenses caused by polyoxyethylene hydrogenated castor oil. The present invention also relates to a method of inhibiting deformation of silicone hydrogel contact lenses due to polyoxyethylene hydrogenated castor oil. In addition, the present invention also relates to a method for suppressing the adsorption of chlorhexidine and / or cyclodextrins on silicone hydrogel contact lenses and reducing the risk of enlargement of silicone hydrogel contact lenses due to polyoxyethylene hydrogenated castor oil. friction method etc. Background technique [0002] In recent years, the number of wearers of contact lenses (CL), especially soft contact lenses (SCL), has increased. It is generally pointed out that when soft contact lenses are worn, the amount of oxygen supplied from the atmosphere decreases, and as ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/155A61K47/34A61K47/40A61P27/02
CPCG02B1/043A61K9/0048A61K31/155A61P27/02A61P31/04C08L83/04C08L71/02
Inventor 松本江利中田温子
Owner ROHTO PHARM CO LTD