441 results about "Polyoxydony" patented technology

The invention provides an additive composition for promoting itraconazole absorption, and the additive composition is prepared from the following components in parts by mass: 20 to 40 parts of modified hydroxypropyl methylcellulose acetic acid succinate, 10 to 25 parts of copovidone, 5 to 15 parts of N-capryloyl sodium salicylate, 2 to 8 parts of nano silicon dioxide and 3 to 10 parts of polyoxyethylene-polyoxypropylene segmented copolymer. According to the additive composition disclosed by the invention, the problems of dissolution rate, bioavailability and stability of the itraconazole oral preparation are comprehensively solved through polymer modification, compounding synergy and parameter optimization, and the process cost is remarkably lower than that of the prior art.

The invention relates to the field of water treatment, and discloses a scale and corrosion inhibitor for seawater circulating cooling water, which is prepared from phosphonic acid grafted maleic anhydride-acrylic acid copolymer, hydroxyethylidene diphosphonic acid, amino trimethylene phosphonic acid, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N-dimethylformamide, N, N- The anti-corrosion coating is prepared from the following raw materials: N, N-diethylaminomethyl-benzotriazole, gamma-aminopropyltriethoxysilane, zinc salt and a polyoxyethylene-polyoxypropylene block copolymer. The core of the invention is that all the raw material components form the thermo-sensitive polyelectrolyte compound through a self-assembly process. The compound is stably dispersed at low temperature by utilizing the cloud point effect of the block copolymer, and is subjected to phase change and preferential deposition on a high-temperature heat exchange surface, so that targeted and efficient delivery of various active components is realized. According to the invention, the problems of incompatibility of components and poor stability of a traditional compound agent are solved, the product has excellent storage stability, and efficient and synergistic corrosion and scaling control can be realized under high-temperature and high-salinity working conditions.

The invention discloses water-soluble soldering paste and a preparation method thereof, and the water-soluble soldering paste comprises the following components in percentage by mass: 85-92% of soldering powder and 8-15% of C soldering flux, the soldering flux C comprises the following components in percentage by mass: 60-95% of soldering flux A and 40-5% of soldering flux B; the soldering flux A comprises a solvent A, a rosin derivative A, a thixotropic agent A, an active agent A and a surfactant; the rosin derivative A comprises at least one of rosin amine and tetrahydroabietinol; the solvent A is a hydrophobic solvent; the mass percent of the rosin derivative A in the soldering flux A is at least 29%; the soldering flux B comprises a solvent B, a rosin derivative B, an active agent B, a thixotropic agent B and a corrosion inhibitor; the solvent B is a hydrophilic solvent; the rosin derivative B comprises polyoxyethylene rosin amine; the soldering flux A and the soldering flux B are used for being compounded into a soldering flux C of an emulsion structure; and the soldering flux C is used for being mixed with soldering powder to form the water-soluble soldering paste.

The invention provides a water-in-oil adjuvant for animal vaccines and a preparation method and application thereof, and relates to the technical field of biology, the water-in-oil adjuvant comprises 73%-75% of oil for injection, 20%-23% of an emulsifier and 2%-7% of a stabilizer; the emulsifying agent is prepared from 4.5 percent to 5 percent of polyoxyethylene fatty alcohol ether, 3.0 percent to 3.5 percent of glycerol monoisostearate, 7.0 percent to 8.0 percent of span 80, 4.5 percent to 5 percent of Tween 80 and 1 percent to 1.5 percent of vitamin E; the vaccine prepared from the water-in-oil adjuvant has the advantages that the viscosity is reduced, and the injection is easy. The technical problems that in the prior art, a vaccine prepared from an oil-in-water adjuvant is large in viscosity, so that resistance is large during injection, the occurrence rate of side reactions is high, an injection part swells, and granuloma is formed are solved.

The present invention provides a blue pigment color paste for a gel pen, the blue pigment color paste contains a blue pigment, a nonionic surfactant, an acrylic resin and water, the nonionic surfactant is a polyoxyethylene polycyclic phenyl ether surfactant, and the acrylic resin is an acrylic resin having an aryl group. The pigment color paste provided by the invention has excellent storage stability, has excellent lubricity after being prepared into ink, and can realize good writing feeling.

The invention discloses water-soluble soldering paste and a preparation method thereof. A soldering flux A comprises a solvent A, a rosin-based material, a thixotropic agent A, an active agent A, a corrosion inhibitor and a surfactant; the rosin-based material comprises at least one of acrylic acid modified rosin, hydrogenated rosin or polyoxyethylene rosin; the soldering flux B comprises a solvent B, a rosin derivative, an active agent B and a thixotropic agent B; the solvent B is a hydrophobic solvent; the rosin derivative comprises at least one of polyoxyethylene rosin amine and polyoxyethylene polymerized rosin; and the soldering flux A and the soldering flux B are compounded into an emulsion structure. Refrigerating the soldering flux A, taking out the soldering flux B, returning to normal temperature, mixing, and emulsifying for 5-10 minutes at the stirring speed of more than 1000rpm to obtain the soldering flux C; and 85-92% of soldering powder is added into 8-15% of the soldering flux C, vacuum uniform mixing is carried out at the stirring speed of 20-40 rpm, and the water-soluble soldering paste is obtained.

The invention discloses a heavy oil composite viscosity reducer and a preparation method thereof. The heavy oil composite viscosity reducer comprises the following components: mahogany petroleum sulfonate, alkylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene polyoxypropylene ether sulfonate, amido gemini quaternary ammonium salt, hexadecyl dimethyl hydroxypropyl betaine, a nano material, an alkaline material and small molecular alcohol. The problems that an existing petroleum sulfonate composite surfactant is still poor in viscosity reducer, temperature resistance and high mineral salt resistance are effectively solved.

The embodiment of the invention provides an electrolyte, a secondary battery and electric equipment, and the electrolyte provided by the embodiment of the invention comprises a lithium salt, an organic solvent and a first additive, the first additive includes a polyoxyethylene polyoxypropylene block copolymer, and the polyoxyethylene polyoxypropylene block copolymer includes a compound of formula (I). The polyoxyethylene group in the compound with the formula (I) is beneficial to reducing the interface impedance between an electrolyte and a pole piece and improving the rate capability of the secondary battery; the polyoxypropylene group in the compound with the formula (I) can also improve the stability of the electrolyte, so that the cycle performance of the secondary battery is improved, and the service life of the secondary battery is prolonged.

Described herein are compositions and methods for modifying eukaryotic cells, for example, to express a transgene of interest and / or to produce an expanded population of cells ex vivo. Using the compositions and methods of the disclosure, a population of eukaryotic cells, such as a population of pluripotent cells (e.g., CD34+ hematopoietic stem or progenitor cells) may be transduced to express a gene of interest by contacting the cells with a viral vector, such as a lentiviral vector, and a diblock copolymer, such as a diblock copolymer composed of a hydrophilic region and a hydrophobic region. For example, the diblock copolymer may be composed of polyoxyethylene (PEO) subunits and polyoxypropylene (PRO) subunits. Additionally, the compositions and methods described herein can be used to promote the proliferation or survival of a population of pluripotent cells (e.g., CD34+ hematopoietic stem or progenitor cells) ex vivo, for example, by contacting the cells with a diblock copolymer.

The invention discloses a metal degreasing agent and a preparation method thereof, and belongs to the technical field of degreasing. Comprising lipase, protease, short-chain fatty acid methyl ester ethoxylate sodium sulfonate, cocamidopropyl betaine, alkyl glucoside, sodium silicate, sodium metasilicate, sodium citrate, disodium ethylene diamine tetraacetate, calcium formate, polyvinyl alcohol-sodium alginate microcapsules, a polyoxyethylene polyoxypropylene block copolymer, sodium carboxymethyl cellulose and water. And the polyvinyl alcohol-sodium alginate microcapsule exists in the metal degreasing agent as a carrier of the lipase and the protease. According to the metal degreasing agent, a microcapsule protection structure is used in the metal degreasing agent, the two technical problems of enzyme-surfactant compatibility and enzyme-alkaline environment compatibility which are difficult to solve for a long time in an industrial degreasing agent are solved, the degreasing agent is easy to actually operate, special equipment is not needed, a traditional degreasing agent can be directly replaced, and the metal degreasing agent is suitable for industrial application. Good market application prospects are realized.

The invention belongs to the technical field of pharmaceutical preparations, and relates to a riptacaine cream as well as a preparation method and application thereof, and the preparation method of the riptacaine cream comprises the following steps: preparing carbomer gel, preparing an oil phase, preparing a water phase, primarily emulsifying, homogenizing and gelating, finely homogenizing and filling. According to the invention, polyoxyethylene (54) hydrogenated castor oil is innovatively used as an auxiliary material, triple functions of a co-melting solvent, an emulsifying agent and a stabilizing agent are realized at the same time, and any liquid grease, solvent or other surfactants do not need to be additionally added in the prescription. Through a unique'water-gel-oil 'composite structure design, oil drops are physically wrapped by a carbomer gel network and are positioned in network pores, so that the mechanical stability superior to that of a conventional emulsion is provided, and no layering is generated through high-speed centrifugal test verification. In conclusion, the invention develops the riptacaine preparation which has the advantages of few types of auxiliary materials, higher stability, quicker effect taking and capability of expanding a new dosage form and a new process.

The application belongs to the technical field of dechlorination carrier and specifically provides a preparation method of a dechlorination active carrier, which comprises the following steps: 1) polyoxyethylene-polyoxypropylene block copolymer and modified protein solution are dissolved in deionized water, then cobalt nitrate, aluminum lactate and 2-aldehyde benzene boronic acid are added and stirred uniformly, reaction is carried out at 110-130 DEG C, centrifugation and drying are carried out to obtain a precursor; 2) tetrabutylphosphonium hydroxide and sodium aluminate are added into deionized water, TEOS and the precursor are added after mixing, stirring is carried out, crystallization is carried out at 165-175 DEG C, centrifugation and washing are carried out, and the obtained solid is dried and calcined to obtain the dechlorination active carrier. The carrier prepared by the application has the advantage of good dechlorination effect.

Filled polyols and processes for their production. The filled polyols include a carrier polyol and polymer particles dispersed in the carrier polyol. The carrier polyol includes a polyether polyol having a functionality of 2 to 6, an OH number of 20 to 120 mg KOH / g, and a poly(oxyethylene) content of at least 60% by weight, based on total weight of the polyether polyol. The polymer particles exhibit a multimodal particle size distribution.

The invention relates to the technical field of waste gas treatment, and particularly discloses waste gas treatment liquid for treating large-air-volume low-concentration waste gas through a water-based method. The waste gas treatment liquid for treating the large-air-volume low-concentration waste gas through the water-based method comprises a surfactant, a defoaming agent, a dissolution accelerant and water. Wherein the surfactant can be selected from any one or more of polyoxyethylene alkyl ether, polyoxyethylene alkyl ether and polyoxyethylene fatty acid ester; the dissolution accelerant can be selected from any one or more of ethylene glycol monobutyl ether, diethylene glycol monobutyl ether and triethylene glycol monobutyl ether; the defoaming agent is any one or more of butanol, dimethyl silicone oil, silicone and polyether modified polysiloxane. When the waste gas absorption liquid obtained in the invention is used for treating waste gas, the absorption efficiency of methanol, butanol, benzene, toluene, xylene, ethyl acetate, dichloromethane and acetone is obviously improved, and the absorption efficiency of the waste gas absorption liquid on aromatic hydrocarbon, halogenated hydrocarbon, alcohol, ketone and ester pollutants is improved.

The invention belongs to the technical field of protein calibration, and particularly relates to an enhanced protein-free confining liquid for protein detection, which comprises the following components: trihydroxymethyl aminomethane, sodium chloride, Tween-20, polyvinyl alcohol, trehalose, EDTA (Ethylene Diamine Tetraacetic Acid) and a polyoxyethylene-polyoxypropylene block copolymer, and sodium chloride and trehalose are matched to provide ions and small molecular compounds to form a stable closed environment. Wherein the trehalose assists in filling and covering small pores of PVDF, the sodium chloride provides ion balance, the EDTA-Na is used for precipitating metal ions, and the Tween-20 assists in repairing the PVDF film. According to the invention, the polyvinyl alcohol and the polyoxyethylene-polyoxypropylene block copolymer are mixed for use, so that non-specific sites on the membrane are blocked while impurity proteins are prevented from being introduced, the sealing effect is achieved, and the problem of false positive or non-specific binding easily caused by the traditional sealing liquid is effectively solved.

The invention discloses a bio-based polyurethane printing ink. Comprising the following raw materials in parts by weight: 10.3 to 22.4 parts of bio-based isocyanate, 25.6 to 34.5 parts of diisocyanate, 40.4 to 52.8 parts of bio-based polyol, 5.7 to 12.4 parts of polypropylene carbonate polyol, 0.5 to 1.2 parts of a catalyst, 3.5 to 9.5 parts of a hydrophilic chain extender, 4.3 to 12.6 parts of an amine chain extender, 2.8 to 6.7 parts of a neutralizing agent, 5.1 to 16.5 parts of water, 6.7 to 18.3 parts of toner, 2 to 5 parts of a thickening agent, 4.2 to 6.8 parts of a curing agent, 2.1 to 4.5 parts of a BYK-425 dispersing agent and 1.5 to 2.3 parts of a TGEO Glide 450 flatting agent. 1.1 to 2.3 parts of polyoxyethylene glycol alkyl ester and 4.7 to 6.2 parts of an antibacterial agent; the invention also discloses a preparation method of the bio-based polyurethane ink. The printing ink is prepared from bio-based isocyanate and bio-based macromolecular polyol through a reaction, has very excellent biocompatibility and biodegradability, and is endowed with an antibacterial function through the antibacterial agent.

The invention relates to an absorbable bone hemostasis and repair stent. The absorbable bone hemostasis and repair stent comprises the following raw materials in parts by weight: 15-60 parts of an excipient, 15-60 parts of a softening agent and 5-70 parts of a bone repair promoting component, the excipient is prepared from a polyoxyethylene-polyoxypropylene copolymer; the softening agent comprises a semi-solid mobile phase polymer; the bone repair promoting component comprises a coating and a core, the coating comprises a polylactic acid-glycolic acid copolymer, zinc stearate and potassium bromide, the core comprises calcium phosphate particles, and the coating wraps the surface of the core. The preparation method comprises the following steps: preparing the bone repair promoting component; and preparing the absorbable bone hemostasis repair stent. The absorbable bone hemostasis and repair stent is high in hemostasis and collapse resistance and has good inflammation regulation and bone repair promoting effects. The absorbable bone hemostasis and repair stent can be used for bone hemostasis and bone repair promotion of any bone injury wound.

The invention discloses a deepening silicone oil emulsion and a preparation method thereof, and relates to the field of deepening silicone oil. The deepening silicone oil emulsion comprises the following raw materials in parts by weight: 55-70 parts of amino modified silicone oil; 30 to 45 parts of acrylate modified polyether silicone oil; 25 to 38 parts of an emulsifier; 1-4 parts of organic acid; 220 to 260 parts of water; the acrylate modified polyether silicone oil comprises the following raw materials in parts by weight: 10-18 parts of hydrogen-containing silicone oil; 6 to 12 parts of allyl polyoxyethylene polyoxypropylene ether; 2-5 parts of an acrylate monomer; 0.5 to 1 part of chloroplatinic acid; the acrylate monomer is selected from one or more of hydroxyethyl acrylate, N-hydroxyethyl acrylamide and 4-hydroxybutyl acrylate. According to the deepening silicone oil prepared by the invention, the deepening silicone oil plays a deepening role, and meanwhile, the influence on the tearing strength and the yellowing problem of fabrics is reduced.

The invention provides an application of polyoxyethylene particles in preparation of a biocompatible preparation for promoting digestive tract mucosal injury repair. The weight-average molecular weight of polyoxyethylene is 1 million Dalton to 7 million Dalton; the average particle size of the polyoxyethylene particles is 0.5 [mu] m to 2000 [mu] m; after the preparation is applied to the injured wound surface of the digestive tract mucosa, colloid covering the injured wound surface of the digestive tract mucosa is formed. The colloid can effectively protect digestive tract mucosa, avoid side effects caused by drug treatment of digestive tract mucosa injury, and provide an effective repair protection barrier for a digestive tract ulcer wound surface or a mucosa injury wound surface, so that the repair of the wound surface is promoted.

The invention relates to a high-efficiency low-toxicity fireproof heat-insulation composite coating and a preparation method thereof, and the preparation raw materials of the high-efficiency low-toxicity fireproof heat-insulation composite coating comprise the following components in parts by weight: 20-30 parts of modified polysiloxane, 15-25 parts of ammonium polyphosphate, 8-15 parts of melamine, 15-28 parts of an inorganic filler, 10-15 parts of water, 5-10 parts of a cosolvent, and 1-3 parts of a functional auxiliary agent. The modified polysiloxane is an A-B-C type three-section type block copolymer, wherein the A section is a polydimethylsiloxane or methyl phenyl siloxane block; the segment B is an organic silicon chain segment containing a phosphazene structural unit; and the segment C is a polyethylene glycol or polyoxyethylene block. According to the invention, the modified polysiloxane is cooperated with the ammonium polyphosphate salt and the melamine, so that the composite coating has the effects of high-efficiency fire prevention and heat insulation, low toxicity, environment friendliness and excellent film forming performance.

Provided is a composition for removing keratosuppository, which has an excellent keratosuppository removal effect and an excellent feeling of use. A composition for removing a keratotic plug according to the present invention contains (A) an alkanolamine compound such as a trialkanolamine, (B) an alkylene oxide derivative such as a polyoxyethylene-polyoxypropylene addition alkyl ether, and (C) water.

The invention relates to the field of coatings, in particular to underwater antifouling paint and a preparation method thereof.The underwater antifouling paint comprises 2-5 parts of chlorinated rubber, 1-3 parts of chlorinated polyether resin, 1-2 parts of zinc acrylate resin, 35-50 parts of an antifouling agent, 9-12 parts of compound rosin, 2-5 parts of a flexibilizer, 1-3 parts of a stabilizer, 2-5 parts of a defoaming agent, 0.1-0.5 part of a dispersing agent, 2-3 parts of a thixotropic agent and 15-25 parts of a solvent; the antifouling agent comprises cuprous oxide, an organic antifouling agent and a natural biological antifouling agent; the compound rosin comprises gum rosin and rosin maleic anhydride polyol ester; the toughening agent is prepared from sorbitan fatty acid ester and tricresyl phosphate; the stabilizer comprises zinc oxide and polyoxyethylene fatty alcohol ether. The underwater antifouling paint disclosed by the invention has relatively high adhesive force, flexibility, impact resistance, water resistance and excellent antifouling property, and is suitable for ship bottoms and underwater facilities.

The invention relates to a power-on adhesive tape capable of losing adhesion and a preparation process thereof. The power-on adhesive tape comprises a base film, a conductive layer and an adhesive layer, the adhesive layer is prepared from the following raw materials in parts by mass: 40 to 50 parts of acrylate copolymer, 3 to 5 parts of terpene resin, 0.2 to 0.5 part of initiator, 20 to 30 parts of solvent, 3 to 5 parts of pyridine modified reduced graphene oxide, 8 to 10 parts of hydroxypropyl-beta-cyclodextrin, 2.0 to 2.4 parts of 1-(2-aminoethyl) ferrocene and 4 to 5 parts of polyethylene glycol diacrylate. The component A is prepared from the following components in parts by weight: 0.5 to 0.8 part of polyoxyethylene-polyoxypropylene-polyoxyethylene triblock copolymer, 0.2 to 0.5 part of benzotriazole antioxidant and 1 to 2 parts of polycarbodiimide; the raw materials of the acrylate copolymer comprise a soft monomer and a hard monomer in a mass ratio of (2.5-3.5): 1. The power-on viscosity-loss adhesive tape is high in peel strength and high in power-on viscosity-loss sensitivity.

The invention relates to the technical field of demulsifiers, in particular to a crude oil demulsifier as well as a preparation method and application thereof. The crude oil demulsifier contains polyether modified organic silicon, amine-terminated polyether, a nano titanium dioxide-graphene compound, polyoxyethylene fatty acid, ammonium persulfate and a novel sulfobetaine derivative; the components are mixed according to a specific proportion; the nano titanium dioxide-graphene compound is prepared through a unique reaction, and the derivative also has an exclusive synthesis path; the demulsifier can reduce interfacial tension, decompose impurities through photocatalysis, adapt to complex crude oil and improve the demulsification effect. The demulsification efficiency is high, the dehydration rate exceeds 90%, and the desalination rate exceeds 80%; the adaptability to high-salt and high-acid-value crude oil is high, organic impurities can be photolyzed, and the quality of the crude oil is improved; and the environment-friendly property is good, and efficient and green development of crude oil extraction and processing is promoted.

The invention provides a fire-retardant coating and a preparation method thereof, belonging to the technical field of coatings. The coating comprises components such as organosilicon-modified epoxy resin, ammonium polyphosphate, melamine cyanurate, modified carbon nanotubes, cage-type silsesquioxane, zirconium boride-modified MOF-808, modified nano-magnesium hydroxide, rutile titanium dioxide, mica powder, vinyl polydimethylsiloxane-polymethylsiloxane silsesquioxane cross-linked polymer, methylsilanol-silicate cross-linked polymer, dimethylthiotoluenediamine curing agent, etc. The modified carbon nanotubes are carbon nanotubes modified by polyoxyethylene fatty acid esters, and the modified nano-magnesium hydroxide is nano-magnesium hydroxide modified by stearic acid. The components are used in combination to have good fire resistance, long fire resistance time, good weather resistance, and long-term performance is not likely to be greatly reduced.

The application discloses an influenza virus extraction diluent and application thereof, and the diluent comprises Na2HPO4*12H2O, NaH2PO4*2H2O, NaCl, Proclin 300, ethylenediaminetetraacetic acid disodium salt dihydrate, polyoxyethylene-8-octylphenyl ether and alkylphenol polyoxyethylene ether. The polyoxyethylene-8-octylphenyl ether and the alkylphenol polyoxyethylene ether added in the diluent improve the virus extraction capacity, enhance the stability of the product, save the cost and time, provide a reference value for other products, prolong the product service life for customers, reduce the limitation, are more suitable for the temperature, and have greater market value.

The application relates to the field of graphene oxide, and discloses modified graphene oxide, which comprises graphene oxide and grafted polyoxyethylene chains, the chemical formula of the polyoxyethylene chains being -CH2CH(OH)CH2O(CH2CH2O) n CH2CH2OH, wherein n is any integer of 3-20; the grafting rate of the polyoxyethylene chains in the modified graphene oxide is 30-50%. The modified graphene oxide has good salt resistance, can resist acid / alkali aqueous solutions, and effectively inhibits the accumulation and agglomeration of graphene oxide.

The present invention provides means with which bile acids, phenols, indoles and organic acids contained in a sample can be stably preserved without cryopreservation of the sample. A sample preservation solution of the present invention is a sample preservation solution used for analyzing at least one component selected from the group consisting of bile acids, phenols, indoles and organic acids contained in a biological or environmental sample, containing at least the following (A) and (B): (A) condensed phosphate or polyoxyethylene sorbitan alkylate; and (B) guanidinium thiocyanate, Tris-HCl (pH 7 to 9), and EDTA.

To provide an oil-based ink composition for a ball-point pen capable of obtaining good handwriting with good writing feeling even in writing at a high speed or at a high writing pressure while effectively suppressing ink leakage, and hardly causing strike-through, and to provide a ball-point pen.SOLUTION: A ballpoint pen refill for an oil-based ballpoint pen includes an ink reservoir tube, an oil-based ink composition filled in the ink reservoir tube, and a ballpoint pen tip attached to a front end portion of the ink reservoir tube and configured to supply the oil-based ink composition, wherein the oil-based ink composition contains a first phosphoric acid ester which is a polyoxyethylene hydrocarbon phosphoric acid ester having a hydrocarbon group having 4 or more and 17 or less carbon atoms, a second phosphoric acid ester which is a polyoxyethylene hydrocarbon phosphoric acid ester having a hydrocarbon group having 18 or more and 24 or less carbon atoms, water, and a nonionic surfactant.SELECTED DRAWING: Figure 1

The application relates to the technical field of medical detection, in particular to a detection kit for total bile acid and a detection kit for total bile acid. The application adds polyoxyethylene-polyoxypropylene copolymer, Span 40 and oxide in R1, and adds EDTA-Na2 and sodium bicarbonate in R2, so that the stability and precision of reagents are effectively improved, and the situation that a negative value is generated in the detection process is solved.