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O/W (Water in Oil) type microemulsion model of fat-soluble nutrient with carbon chain length of (15 and preparation method thereof

A technology with fat-soluble nutrients and long carbon chain, applied in food preparation, emulsion delivery, metabolic diseases, etc., can solve problems such as limited regularity relationship, and achieve the effect of promoting perfection, saving formulation optimization time, and enhancing chemical stability.

Inactive Publication Date: 2012-07-11
JIANGNAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the studies are only on the optimization of the formula for a specific target embedding, and the chemical structure, compatibility and microemulsion formation ability of surfactants, co-surfactants and embeddings in the process of microemulsion formation, Research on the regular relationship between microemulsion structures is still very limited

Method used

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  • O/W (Water in Oil) type microemulsion model of fat-soluble nutrient with carbon chain length of (15 and preparation method thereof
  • O/W (Water in Oil) type microemulsion model of fat-soluble nutrient with carbon chain length of (15 and preparation method thereof
  • O/W (Water in Oil) type microemulsion model of fat-soluble nutrient with carbon chain length of (15 and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Take vitamin E acetate 10g, choose Brij 56 as emulsifier, select ethanol as co-emulsifier, the mass ratio of emulsifier and co-emulsifier is 2:1, take the total amount of emulsifier and co-emulsifier as 30g, stir and mix Finally, add water to dilute and stir and mix for later use. The add-on of water is 65g, and it is packed in brown glass bottles according to the required dose, so that the O / W type vitamin E acetate microemulsion of the present invention is obtained.

Embodiment 2

[0027] Get β-carotene ethyl butyrate saturated oil solution 8g, select Tween 60 as emulsifier, co-emulsifier selects ethanol, the mass ratio of emulsifier and co-emulsifier is 2:1, take emulsifier and co-emulsifier The total amount is 15g. After stirring and mixing, add water to dilute and stir to mix for use. The amount of water added is 75g, and it is divided into brown glass bottles according to the required dose, so that the O / W type β- Carotene ethyl butyrate microemulsion.

Embodiment 3

[0029] Take 8g of sweet orange oil, select Tween 80 as emulsifier, choose ethanol as co-emulsifier, the mass ratio of emulsifier and co-emulsifier is 1:1, take the total amount of emulsifier and co-emulsifier as 16g, stir and mix After that, add water to dilute and stir and mix for later use, the add-on of water is 75g, is packed in the glass bottle according to required dose, promptly makes the sweet orange oil microemulsion of O / W type of the present invention.

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Abstract

The invention provides an O / W (Water in Oil) type microemulsion model of a fat-soluble nutrient with carbon chain length of (15 and a preparation method thereof, and belong to the technical field of microemulsion preparation. The microemulsion is widely applied due to good stability and solubilization characteristic. Currently, multiple formula optimization researches are made on specific oil-phase microemulsion; and in the researches, selection and mixing ratio optimization of a surfactant, a cosurfactant, a water phase and an oil phase are carried out on different embedded substances every time. According to the invention, an universal O / W type fat-soluble nutrient microemulsion formula model is established; and the model can be used for instructing and simplifying microemulsion formula selection of non-long-chain fat-soluble nutrients, such as vitamin E, acetate, lemon essential oil, sweet orange oil, a beta-carotene ethyl butyrate saturated oil solution and the like, so that a basis of rapidly determining microemulsion formula is provided for the preparation of the O / W type fat-soluble nutrient microemulsion and the completion of the microemulsion nanometer technology is promoted.

Description

technical field [0001] A microemulsion model of O / W type non-long-chain (carbon chain length<15) fat-soluble nutrients, the present invention relates to a microemulsion model of O / W type fat-soluble nutrients, specifically a nanoscale particle The non-long-chain (carbon chain length <15) fat-soluble nutrient emulsion model belongs to the technical field of microemulsion preparation. Background technique [0002] In the fields of food and biotechnology, with the continuous exploration of the excellent properties of nanomaterials, nanotechnology has gradually occupied the attention of human beings. Microemulsion is a special one in nanotechnology. It is an isotropic, transparent or translucent appearance, and thermodynamically stable dispersion system spontaneously formed by an appropriate proportion of surfactants, co-surfactants, water and oil. Its particle size is generally between 1-100nm. In addition, microemulsion nanotechnology also has the characteristics of fi...

Claims

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Application Information

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IPC IPC(8): A23L1/29A61K9/107A61P3/02A23L33/00
Inventor 李玥钟芳王海洋
Owner JIANGNAN UNIV
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