Extract of willow barks or willow branches and method for preparing salicin

Abstract

The invention belongs to the technical field of chemical engineering and particularly relates to an extract prepared by using willow barks or willow branches as raw materials, and a method for preparing high-purity salicin, aiming at providing a method for extracting high-content salicin from the willow barks or the willow branches. The method comprises the following steps of: (A) taking the willow barks or the willow branches as the raw materials and carrying out extraction by using an aqueous or alcoholic solution, (B) filtering an extracted solution, (C) carrying out resin adsorption separation on a filtrate, (D) decolorizing, and (E) crystallizing and is characterized in that: an ultrafiltration manner is adopted to filter when the filtration is carried out in the step (B), the extracted solution is firstly filtered by using a 100-500 kD ultrafiltration membrane and then is filtered by using a 5-10 kD ultrafiltration membrane, and the average membrane fluxes are respectively controlled at 100-190 LMH and 20-24 LMH. According to the method provided by the invention, the steps of extraction and ultrafiltration are adopted in coordination with the processes of adsorption, decolorization, crystallization and the like, the content of the obtained salicin can reach 99.0%, the yield is high, the cost is low, and the water and a small amount of alcohol which are used in production can be recycled, so that the cost is lowered, the pollution to the environment caused by organic solvents is reduced, and the implementation of industrialization is facilitated.

Description

technical field [0001] The invention relates to the technical field of chemical engineering, in particular to an extract prepared from willow bark or willow branches and a preparation method for extracting high-purity salicin from willow bark or willow branches. Background technique [0002] Salicin (salicin), also known as salicin, chemically named 2-hydroxymethylbenzene-β-D-glucopyranoside, can be extracted from willow bark or willow branches, or through the condensation of salicyl alcohol and glucose get. [0003] The content of salicin in general raw materials (willow bark or willow branches) is between 1.0% and 5.0%. Its use history can be traced back to 3000 BC, and its main uses are anti-inflammatory, analgesic, and fever-reducing. Salicin and aspirin (acetylsalicylic acid) have similar biological activities, and are not irritating to the stomach, and are less likely to cause gastric bleeding. New research has found that it is an inhibitor of NADH oxidase, which ha...

AI Technical Summary

Problems solved by technology

This process consumes a large amount of organic solvents during the extraction process, which is costly and not conducive to environmental protection, and the content cannot reach more than 99%.

[0008] These two preparation processes need to mix the raw materials with quicklime and an appropriate amount of water first, and the quicklime powder strongly irritates the eyes and skin of the workers during the sample mixing process, which is not conducive to the health of the workers, and a large amount of organic reagents used will have a negative impact on the health of the workers. environmental hazard

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