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Method for processing alangium platanifolium

An octagonal maple and processing technology, applied in the field of traditional Chinese medicine processing, can solve the problems that the safety of the octagonal maple cannot be improved, and the detoxification effect of the medicinal material is not obvious.

Active Publication Date: 2012-07-18
北京创立科创医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This method is a conventional processing method of traditional Chinese medicine, and the detoxification effect on the medicinal materials is not obvious after processing, and the drug safety of the star anise maple cannot be improved.
[0005] Up to now, there is no processing technology that can stably and effectively reduce the toxicity of star anise maple and is convenient for industrial application

Method used

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  • Method for processing alangium platanifolium
  • Method for processing alangium platanifolium
  • Method for processing alangium platanifolium

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: the processing method of star anise maple

[0021] This experiment provides the processing technology under different dosage ratios, and it is intended to screen out the best processing parameters of the star anise maple processing technology from the follow-up experiments.

[0022] Process 1:

[0023] According to the processing steps provided by the present invention, according to the ratio of every 1000 parts of star anise maple crude drug, 100 parts of licorice, and 250 parts of milk, a batch of star anise maple is processed, and the specific operations are as follows:

[0024] 1) Purchase a batch of star anise maple medicinal materials, select and cut into long sections, about 5cm long;

[0025] 2) weigh the star anise maple medicinal material after the above-mentioned cutting into sections, weighing about 2000g;

[0026] 3) Preparation of licorice juice: Weigh 200g of licorice, decoct twice, add 2L of water each time, first boil with "high fire" u...

Embodiment 2

[0044] Comparative Study on the Acute Toxicity and Muscle Relaxation of the Star Anise Maple Processed by Different Processing Methods 1 Experimental materials

[0045] 1.1 Experimental drugs

[0046] Sample No. 1: Raw medicinal material of star anise maple (unprocessed), the equivalent crude drug amount is 1.08g / g, batch number: SP001.

[0047] Sample No. 2: medicine after frying rice wine with star anise maple medicinal material (add 100g rice wine for every 1000g crude drug and stir-fry until the sample is crisp), the equivalent crude drug amount is 1.25g / g, batch number: PZP001.

[0048] Sample No. 3: Stir-fried star anise maple medicinal material (fried until the sample is crisp), the equivalent crude drug content is 1.30g / g, batch number: PZP002.

[0049] Sample No. 4: boiled licorice milk, an aniseed maple medicinal material (processed according to the process 1 provided in Example 1), the equivalent crude drug amount is 1.14g / g, batch number: PZP003.

[0050] Sam...

Embodiment 3

[0091] Embodiment 3 The stability test of processing technique of the present invention

[0092] 3.1 In order to verify the stability and feasibility of the processing technology provided by the present invention, the present invention has completed the pilot-scale scale-up research of 10 batches of star anise maple from 3 production areas, and tested each batch of samples, and the results are as shown in table 4 .

[0093] Table 4 10 batches of pilot scale-up data

[0094]

[0095] 3.2

[0096] Table 5 Determination results of star anise maple alkali content in raw and processed products of star anise maple from different origins

[0097]

[0098] 3.3 Stability investigation and research

[0099] The present invention has carried out stability research on 3 batches of pilot products produced continuously at room temperature, and has completed 12 months of stability research work, and the results are shown in Table 6-8. The results show that the quality of this produ...

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Abstract

The invention provides a method which is applicable to process alangium platanifolium, as for the alangium platanifolium, alkaloid is not only the active ingredient but also the toxic ingredient of the alangium platanifolium. Consequently, the research on the method for safely and reasonably processing the drug is very important to improve the clinic medication safety of the drug. The method for processing the alangium platanifolium is scientific and reasonable, has stable technological parameters, can effectively improve the safety of the alangium platanifolium to realize the purposes of toxicity reduction and efficacy enhancement, and benefits industrial production.

Description

technical field [0001] The invention relates to a processing method of traditional Chinese medicine, in particular to a processing method suitable for the traditional Chinese medicine star anise maple. Background technique [0002] The star anise maple is the dry fine root and fibrous root of the star anise maple plant Alangium chinense (Lour.) Harms. Distributed in Yunnan, Guizhou and other places, it is used as medicine for ethnic minorities. It has the effects of expelling wind and dredging collaterals, dissipating stasis, analgesia, anesthesia and muscle relaxation, etc. It is used to treat rheumatism pain, numbness and paralysis, heart failure, strained low back pain, bruises, etc. Its fibrous roots and branch roots contain alkaloids, acids, amino acids, organic acids, resins, etc. Star anise maple has broad research and development prospects because of its reliable curative effect, wide range of drug sources, and economical convenience. [0003] The alkaloids of sta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P9/04A61P29/00
Inventor 和芳高柏丽胡玉霞何渭清王学智祁春艳
Owner 北京创立科创医药技术开发有限公司
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