Medicinal coating stent

Abstract

Interventional therapy at the bifurcation of blood vessels is a difficult point in clinic, and particularly stents in the bifurcated blood vessels are difficult to introduce, and the restenosis rate is high in the later period due to high possibility of pathological changes such as thrombus, intimal hyperplasia and the like. Aiming at the problem, the invention provides a design scheme of the medicinal coating stent. In the design scheme, a section of part of which has the medicinal concentration is uniform and is higher than that of other parts is positioned in the stent; and the part with the high medicinal concentration corresponds to inlets of the bifurcated blood vessels, so that medicinal ingredients act on the bifurcated blood vessels, excessive medicinal ingredients can be applied in main blood vessels, the probability of the pathological changes such as thrombus, intimal hyperplasia and the like in the bifurcated blood vessels is reduced, and the operation of implanting the stent in the bifurcated blood vessels independently is avoided.

Description

technical field [0001] The invention relates to a drug-coated stent, in particular to a drug-coated stent for blood vessel bifurcations. Background technique [0002] At present, the main problem faced by interventional treatment of coronary artery stents is the problem of late in-stent restenosis, especially in-stent restenosis at the coronary bifurcation. There are about 1 million patients treated with percutaneous coronary intervention (PCI) every year in the world, and interventional treatment of coronary bifurcation lesions accounts for about 20% of the total number of PCIs, while the incidence of in-stent restenosis is as high as 30%. . The reason is, on the one hand: the blood flow at the bifurcation of the blood vessel is unstable, and the mechanical environment at the bifurcation of the blood vessel after the stent is implanted is very complicated, which easily induces atherosclerosis, thrombosis and plaque and other lesions. On the other hand, the implantation an...

AI Technical Summary

Problems solved by technology

The reason is, on the one hand: the blood flow at the bifurcation of the blood vessel is unstable, and the mechanical environment at the bifurcation of the blood vessel after the stent is implanted is very complicated, which is easy to induce atherosclerosis, thrombosis, plaque and other lesions

On the other hand, the stent implantation and positioning at the vascular bifurcation are also more difficult than the single vascular stent implantation

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