Application of nilestriol compound in preparing information treatment drug, preparation method and prepared novel drug

Abstract

The invention discloses application of a nilestriol compound in preparing an information treatment drug, a preparation method of the nilestriol compound and a novel drug prepared by the method. During the treatment, the information treatment drug does not directly touch a human body, drug substance components are not consumed, chemotherapy effects can be achieved only by drug information physiotherapy, and the therapy window is enlarged more than one thousand times, and side effects of the chemotherapy are avoided. After nilestriole is used as the information treatment drug, the effective component content is not changed, and nilestriole can be used secondarily and effectively as a chemotherapy normal preparation.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a novel medicine of nylestriol. Background technique [0002] Compound Nylestride, chemical name: 3-(cyclopentyloxy)-19-nor-17-pregna-1,3,5(10)-triene-20yne-16a, 17a -diol, chemical formula C 25 h 32 o 3 , molecular weight 380.53. Appearance is white crystalline powder. Nylestriol is an estrogen drug, clinically used to treat diseases caused by estrogen deficiency. The pharmaceutical preparations of nylestriol include tablets, capsules, etc. The known nylestriol drugs are all used as chemotherapeutic drugs, which allow the compound nylestriol molecules to enter the human body (through oral absorption into the blood), distribute to various tissues, and produce drugs through chemical reactions of drug molecules in the human body. pharmacological effects. In the prior art, nilestriol has insurmountable defects as a chemotherapeutic drug. The first is its toxic and side effects on th...

AI Technical Summary

Problems solved by technology

In the prior art, nilestriol has insurmountable defects as a chemotherapeutic drug. The first is its toxic and side effects on the human body, and its annoying adverse reactions include breast swelling and pain, increased leucorrhea, breakthrough bleeding, Nausea, abdominal distension, liver function damage, dizziness, headache, high blood pressure, and increased risk of endometrial cancer; second, the treatment window is small, and due to the toxic and side effects on the human body, the effective dose that can be used is very small, which limits Therapeutic effect, the maximum dose of oral administration is 2 mg once, 5 mg a day, if the maximum dose is exceeded, it may cause poisoning; the third is that there is only one use of chemotherapeutic drugs, and the drugs will be metabolized and decomposed or excreted when they enter the human body, so they cannot be used twice

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