Automatic drug delivery system for hydroxylcamptothecin injection

A technology of hydroxycamptothecin and automatic drug administration, which is applied to the devices introduced into the body, etc., to achieve the effect of easy operation, safe and reliable use, and uniform drug administration

Inactive Publication Date: 2014-04-09
黄石燕舞药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the existing automatic drug delivery system is generally a uniform delivery of a certain dosage within a certain period of time, which is not suitable for this intermittent delivery of hydroxycamptothecin. In order to improve the curative effect and reduce adverse reactions, There is a need for an automatic dosing system for intermittent administration of hydroxycamptothecin

Method used

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  • Automatic drug delivery system for hydroxylcamptothecin injection
  • Automatic drug delivery system for hydroxylcamptothecin injection

Examples

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Embodiment Construction

[0036] The present invention will be further described below in conjunction with specific examples.

[0037] Take hydroxycamptothecin for injection (specification 10mg) dissolved in 100ml 0.9% sodium chloride injection, administer for 30 minutes, stop for 30 minutes, administer ten times as an example.

[0038] refer to figure 1 The schematic diagram of the module and figure 2 Schematic diagram of the drug administration process, as shown in the figure, put the prepared hydroxycamptothecin liquid into the infusion module, and confirm the dosage plan through the keyboard button of the human-computer interaction module: the total amount of drug administration is 100ml, and the drug is administered for 30 minutes , Stop for 30 minutes, ten times of administration, machine failure, blockage, air bubbles, no liquid, low battery, infusion will end, and the end of infusion will give an alarm. The computer processing module receives the signal, stores the dosing plan, an...

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PUM

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Abstract

The invention discloses an automatic drug delivery system and a drug delivery method for hydroxycamptothecin injection. The automatic drug delivery system comprises an infusion module, a human-computer interaction module, a display module, a timing module, a motor execution module, an alarm monitoring module and a computer processing module. The drug delivery method includes: inputting prepared liquid medicine into the infusion module, setting or confirming drug delivery amount, drug delivery time, intermittent time, drug delivery times and alarm information; monitoring whether warning information exists or not, and if not, operating first-time drug delivery while the timing module starts timing; when the set drug delivery time is up, allowing a motor to pause to enter a low-power-consumption mode while timing is unstopped; when the set intermittent time is up, automatically increasing the drug delivery times by one, and allowing a motor module to reoperate to start next-time drug delivery; and finishing drug delivery when drug delivery times in operation is larger than the initially set drug delivery times. Using the system and the method can improve curative effects of hydroxycamptothecin and reduce drug toxic and side effects, and accordingly quality of life can be improved for patients.

Description

technical field [0001] The invention relates to a drug delivery system, in particular to an automatic drug delivery system which is specially used for hydroxycamptothecin injection and can be administered intermittently. Background technique [0002] Hydroxycamptothecin (HCPT for short) is a natural alkaloid extracted from the unique plant camptophylla in my country. It has been widely used clinically in many countries. [0003] HCPT presents a two-compartment model in vivo, t 1／2α is 0.0523-0613h,t 1／2β For 1.03-2.42h, Vd: 5.4-11.40 L, plasma protein binding rate is 65% to 99%. Bone marrow suppression is a dose-limiting adverse reaction of HCPT, manifested as neutropenia in a dose-dependent manner, and granulocytes return to normal levels within 1-2 weeks after drug withdrawal. Gastrointestinal reaction: Nausea, vomiting I-II degree, duration mostly 2-3d. Diarrhea increased with the dose, and the occurrence ratio was dose-dependent, and the degree of diarrhea was mild i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M5/14
Inventor 吴汉强
Owner 黄石燕舞药业有限公司
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